Fern, Robert - Plymouth University

个人简介

Qualifications Education 1992 Ph.D., University College London, Universityof London. 1988 HDQC (B.Sc.), St Thomas's, University of London. Post-Doc,Department of Neurology, Yale University. Positions 2013-present Professor, University of Plymouth 2010-2013 Professor, University ofLeicester. 2002-2010 Reader in Neuroscience,University of Leicester. 2002-2011 Affiliate Faculty Neurology,University of Washington. 1996-2002 AssistantProfessor, Department of Neurology, University of Washington. 1994-1996 Associate Research Scientist,Department of Neurology, Yale University.

研究领域

My laboratory is primarily interested in the kinds of injury that occurs in the brain following loss of blood supply. These ischemic injuries may take place in he adult brain, leading to stroke; or in the developing nervous system,leading to cerebral palsy. Stroke is the third biggest killer in Western society while cerebral palsy is the most common neurological disorder of infancy, affecting 3:1000 babies. Neither stroke nor cerebral palsy have affective treatments and we are working to understand how the brain cells are injured in these disorders so that we can intervene.

近期论文

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Parpura V, Sekler I & Fern R 2016 'Plasmalemmal and Mitochondrial Na+-Ca2+ Exchange in Neuroglia' GLIA 64, (10) 1646-1654 Author Site , DOI Quraishe S, Wyttenbach A, Matinyarare N, Perry VH, Fern R & O'Connor V 2016 'SELECTIVE AND COMPARTMENTALIZED MYELIN EXPRESSION OF HspB5' NEUROSCIENCE 316, 130-142 Author Site , DOI Hansen DB, Garrido-Comas N, Salter M & Fern R 2015 'HCO3--independent pH Regulation in Astrocytes in Situ Is Dominated by V-ATPase' JOURNAL OF BIOLOGICAL CHEMISTRY 290, (13) 8039-8047 Author Site , DOI Fern R 2015 'Ischemic tolerance in pre-myelinated white matter: the role of astrocyte glycogen in brain pathology' J Cereb Blood Flow Metab 35, (6) 951-958 Author Site , DOI Alghamdi B & Fern R 2015 'Phenotype overlap in glial cell populations: astroglia, oligodendroglia and NG-2(+) cells' FRONTIERS IN NEUROANATOMY 9, Author Site , DOI Alghamdi B & Fern R 2015 'Phenotype overlap in glial cell populations: astroglia, oligodendroglia and NG-2(+) cells' FRONTIERS IN NEUROANATOMY 9, Author Site , DOI Huria T, Beeraka NM, Al-Ghamdi B & Fern R 2015 'Premyelinated central axons express neurotoxic NMDA receptors: relevance to early developing white-matter injury' J Cereb Blood Flow Metab 35, (4) 543-553 Author Site , DOI Trotman M, Vermehren P, Gibson CL & Fern R 2015 'The dichotomy of memantine treatment for ischemic stroke: dose-dependent protective and detrimental effects' J Cereb Blood Flow Metab 35, (2) 230-239 Author Site , DOI Fern RF, Matute C & Stys PK 2014 'White matter injury: Ischemic and nonischemic' Glia 62, (11) 1780-1789 Author Site , DOI Alix JJP, Zammit C, Riddle A, Meshul CK, Back SA, Valentino M & Fern R 2012 'Central Axons Preparing to Myelinate Are Highly Sensitivity to Ischemic Injury' ANNALS OF NEUROLOGY 72, (6) 936-951 Author Site , DOI