Edwards, James - Plymouth University

个人简介

Role Lecturer in Biomedical Science Qualifications I joined PU PSMD as a Lecturer in Biomedical Science in 2013. I previously worked as a research scientist and Teaching Fellow at the University of York. I have worked on a variety of research projects, both in industry and academia, with the most recent studying respiratory processes and growth physiology in pathogenic bacteria. At York I taught on a number of biochemistry modules and supervised undergraduate project students. At Plymouth, my position allows me to focus on teaching our BMBS students about various topics in microbiology. Qualifications BSc (Hons) Microbiology, University of Surrey, 2002 PhD, Department of Biology, University of York, 2006 PGCAP, University of Plymouth, 2014

研究领域

Microbial Biochemistry I am interested in the growth physiology of bacterial pathogens, how they respire and how they regulate the transcription of respiratory genes. I have used in vitro and in vivo approaches in the past to investigate this, including gene cloning, protein over-expression and purification, DNA binding assays, gene knock-outs and reporter gene fusions. Science Education I have undertaken the Postgraduate Certificate in Academic Practice (PGCAP). I am particularly interested in how microbiology is taught nationally, both in science and healthcare curricula.

近期论文

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Aas FE, Li X, Edwards J, Hongrø Solbakken M, Deeudom M, Vik Å, Moir J, Koomey M & Aspholm M 2015 'Cytochrome c -based domain modularity governs genus-level diversification of electron transfer to dissimilatory nitrite reduction' Environmental Microbiology 17, (6) 2114-2132 , DOI Catenazzi MCE, Jones H, Wallace I, Clifton J, Chong JPJ, Jackson MA, Macdonald S, Edwards J & Moir JWB 2014 'A large genomic island allows Neisseria meningitidis to utilize propionic acid, with implications for colonization of the human nasopharynx' Mol Microbiol 93, (2) 346-355 Author Site , DOI Edwards J, Quinn D, Rowbottom K-A, Whittingham JL, Thomson MJ & Moir JWB 2012 'Neisseria meningitidis and Neisseria gonorrhoeae are differently adapted in the regulation of denitrification: single nucleotide polymorphisms that enable species-specific tuning of the aerobic-anaerobic switch' Biochem J 445, (1) 69-79 Author Site , DOI Rylott EL, Jackson RG, Sabbadin F, Seth-Smith HMB, Edwards J, Chong CS, Strand SE, Grogan G & Bruce NC 2011 'The explosive-degrading cytochrome P450 XplA: biochemistry, structural features and prospects for bioremediation' Biochim Biophys Acta 1814, (1) 230-236 Author Site , DOI Edwards J, Cole LJ, Green JB, Thomson MJ, Wood AJ, Whittingham JL & Moir JWB 2010 'Binding to DNA protects Neisseria meningitidis fumarate and nitrate reductase regulator (FNR) from oxygen' J Biol Chem 285, (2) 1105-1112 Author Site , DOI Seth-Smith HMB, Edwards J, Rosser SJ, Rathbone DA & Bruce NC 2008 'The Explosive-Degrading Cytochrome P450 System Is Highly Conserved among Strains of Rhodococcus spp' Applied and Environmental Microbiology 74, (14) 4550-4552 , DOI Rylott EL, Jackson RG, Edwards J, Womack GL, Seth-Smith HMB, Rathbone DA, Strand SE & Bruce NC 2006 'An explosive-degrading cytochrome P450 activity and its targeted application for the phytoremediation of RDX' Nat Biotechnol 24, (2) 216-219 Author Site , DOI