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个人简历: 2022.01-目前 副研究员,上海中医药大学 创新中药研究院 手性药物研究中心 2020.07-2021.12 助理研究员,上海中医药大学 创新中药研究院 手性药物研究中心 2018.03-2020.06 师资博士后,上海中医药大学,中药学专业,合作导师:林国强 研究员(院士) 2014.09-2017.06 博士,中国科学院海洋研究所,海洋生物学专业 (导师:孙超岷 研究员) 2011.9-2014.6 硕士,中国科学院微生物研究所,病原生物学专业(导师:朱宝利研究员) 2007.9-2011.6 本科,山东农业大学,动物检疫专业 (导师:牛钟相 教授) 学术荣誉: 上海市教育委员会“晨光计划” 2021 主持科研项目: 课题名称 项目名称 起止时间 金额 艾曲波帕靶向HuR蛋白抑制乳腺癌转移的作用与分子机制研究 国家自然科学基金青年基金 2021.1-2023.12 24万 HuR蛋白作为新型抗肿瘤血管生成抑制剂作用靶点的可行性研究 上海市自然科学基金 2020.7-2023.6 50万 HuR抑制剂NQ-2抗神经胶质6瘤的活性与作用机制研究 上海市教育委员会“晨光计划” 2022.1-2023.12 6万 靶向性抗肿瘤药物ELB的活性验证与作用机理研究 中国博士后科学基金 2019.1-2020.12 5万 基于HuR-VEGF mRNA相互作用的靶向性抗肿瘤药物ELB的活性验证与作用机理研究 上海中医药大学预算内科研项目 2019.1-2020.12 5万 基于新型抗肿瘤靶点HuR蛋白的体外高通量筛选体系构建与中药来源活性物质的筛选 上海市卫生和计划生育委员会中医药科研课题 2018.9-2020.9 3万

研究领域

药物筛选 药物作用机理

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Yuying Zhu,# Liuqing Yang,# Jiazhen Xu,#Xiyan Yang, Pengwei Luan, Qianfei Cui, Pei Zhang, Feiyun Wang, Ruixiang Li, Xinyue Ding, Lixian Jiang, Guoqiang Lin, and Jiange Zhang* Discovery of the anti-angiogenesis effect of eltrombopag in breast cancer through targeting of HuR protein. Acta Pharm Sin B 2020, 10(8), 1414−1425. (IF = 11.413) 2. Liuqing Yang,# Shaopeng Yu,# Yantao Yang, Yishuang Zhao, Feiyun Wang, Yao Chen, Qinghua Li, Ping Tian,* Yuying Zhu,* Jiange Zhang,* and Guoqiang Lin Muscone derivative ZM-32 inhibits breast tumor angiogenesis by suppressing HuR-mediated VEGF and MMP9 expression. Biomedicine & Pharmacotherapy 2021, 136, 111265. (IF = 6.529) 3. Lixian Jiang,# Yuying Zhu,# Pengwei Luan, Jiazhen Xu, Ge Ru, Yuwei He, Jianguo Fu, Nina Sang, Yang Xiong, Guoqiang Lin, Jianxin Wang, Jiange Zhang,* and Ruixiang Li* Bacteria-anchoring hybrid liposome capable of absorbing multiple toxins for anti-virulence therapy of Escherichia coli infection. ACS Nano 2021, 15, 4173−4185. (IF = 15.881) 4. Shaopeng Yu,# Yuying Zhu,# Jiaruo Xu, Guangtao Yao, Pei Zhang, Mengge Wang, Yongfang Zhao, Guoqiang Lin, Hongzhuan Chen,* Lili Chen,* and Jiange Zhang* Glycyrrhizic acid exerts inhibitory activity against the spike protein of SARS-CoV-2. Phytomedicine 2021, 85, 153364. (IF = 5.340) 5. Shaopeng Yu,# Yao Chen,# Yusen Xiang,# He Lin, Mengge Wang, Wenbo Ye, Pei Zhang, Hongzhuan Chen, Guoqiang Lin, Yuying Zhu,* Lili Chen,* and Jiange Zhang* Pseudoephedrine and its derivatives antagonize wild and mutated severe acute respiratory syndrome-CoV-2 viruses through blocking virus invasion and antiinflammatory effect. Phytotherapy Research 2021, 35(10), 5847−5860. (IF = 5.878) 6. Jiazhen Xu,# Pei Zhang,# Yao Chen,# Yulan Xu, Pengwei Luan, Yuying Zhu,* and Jiange Zhang* Sodium tanshinone IIA sulfonate ameliorates cerebral ischemic injury through regulation of angiogenesis. Experimental and Therapeutic Medicine 2021, 22(4), 1122. (IF = 2.447) 7. Yuying Zhu, Pei Huang, Na Yang, Rui Liu, Xueting Liu, Huanqin Dai, Lixin Zhang, Fuhang Song,* and Chaomin Sun* Establishment and application of a high throughput screening system targeting the interaction between HCV internal ribosome entry site and human eukaryotic translation initiation factor 3. Frontiers in Microbiology 2017, 8, 977. (IF = 5.640) 8. Yuying Zhu,# Ning Ma,# Weihua Jin, Shimei Wu, Chaomin Sun* Genomic and transcriptomic insights into the calcium carbonate biomineralization by marine Actinobacterium brevibacterium lines BS258. Frontiers in Microbiology 2017, 8, 602. (IF = 5.640) 9. Fei Liu,# Yuying Zhu,# Yong Yi, Na Lu, Baoli Zhu,* and Yongfei Hu* Comparative genomic analysis of Acinetobacter baumannii clinical isolates reveals extensive genomic variation and diverse antibiotic resistance determinants. BMC Genomics 2014, 15, 1163. (IF = 3.969) 10. Yuying Zhu, Yong Yi, Fei Liu, Na Lu, Xi Yang, Jing Li, Yongfei Hu,* and Baoli Zhu* Distribution and molecular profiling of class 1 integrons in MDR Acinetobacter baumannii isolates and whole genome-based analysis of antibiotic resistance mechanisms in a representative strain. Microbiological Research 2014, 169, 811−816. (IF = 5.415)

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