个人简介
招生专业：
院系名称 专业大类 一级学科 专业代码/专业名称 学位类型 招生类型
创新中药研究院 理学 中药学 100800/中药学 学术型 硕士
个人简历：
2021.01-目前
副研究员，上海市中医药大学创新中药研究院手性药物研究中心
2020.07-2020.12 助理研究员，上海市中医药大学创新中药研究院手性药物研究中心
2018.06-2020.06 师资博后，上海中医药大学，中药学专业，合作导师：林国强院士
2012.09-2018.06 博士，复旦大学，药物化学专业（导师：李英霞教授）
2008.09-2012.06 本科，郑州大学，药物制剂专业
学术荣誉：
上海中医药大学“杏林青年学者” 2020
上海市青年科技英才“扬帆计划” 2020
上海中医药大学“十大杏林菁英” 2020
主持科研项目：
课题名称 项目名称 起止时间 金额
靶向肿瘤代谢新型PHGDH抑制剂的设计合成及生物活性评价 国家自然科学基金青年基金 2020.01-2022.12 20万
靶向肿瘤代谢新型PHGDH抑制剂的设计合成及作用机制研究 上海市青年科技英才“扬帆计划” 2019.05-2022.04 20万
FABP4／FABP5双靶点抑制剂的设计合成及生物活性评价 中国博士后科学基金 2018.11-2020.07 5万
中药活性成分牛蒡子苷元及其衍生物对STAT3信号通路的活性研究
上海中医药大学预算内科研项目 2019.01-2020.12 5万
近期论文
查看导师最新文章
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1. Cheng-Yu He#, Yun-Xuan Tan#, Xin Wang, Rui Ding, Yi-Fan Wang, Feng Wang, Dingding Gao*, Ping Tian *, Guo-Qiang Lin*. Copper(I)-Catalyzed Diastereo- and Enantioselective Construction of Optically Pure Exocyclic Allenes. Nat. Commun.2020,11, 4293. (IF=12.121)
2. Jia-Ying Zhao, Kai-Rui Feng, Feng Wang, Jian-Wei Zhang, Jay Fei Cheng*, Guo-Qiang Lin, Dingding Gao*, Ping Tian*. A Retrospective Overview of PHGDH and Its Inhibitors for Regulating Cancer Metabolism. Eur. J. Med. Chem.,2021, 217, 113379. (IF=5.572)
3. Dingding Gao#, NanJin#, Yixian Fu, Yueyue Zhu, Yujie Wang, Ting Wang, Yuehong Chen, Mingming Zhang, QiangXiao, Min Huang, Yingxia Li. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors. Eur. J. Med. Chem.,2021, 216, 113333. (IF=5.572)
4. Kai-Rui Feng#, Feng Wang#, Xin-Wei Shi, Yun-Xuan Tan, Jia-Ying Zhao, Jian-Wei Zhang, Qing-Hua Li*, Guo-Qiang Lin, Dingding Gao*, and Ping Tian*. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy. Eur. J. Med. Chem.,2020, 201, 112428. (IF=5.572)
5. Dingding Gao#, Xing-Yu Liu#, Hao Xu#, Yun-Xuan Tan, Qi Liao, Qing-Hua Li*, Xiaodi Yang, Guo-Qiang Lin*, and Ping Tian*. One-Pot Preparation of 9,10-Dihydrophenanthrenes Initiated by Rhodium(III)-Catalyzed C−H Activation and Relay Diels-Alder Reaction. Org. Lett. 2020, 22, 4300−4305. (IF=6.091)
6. Dingding Gao+, Feng Wang+, Xing-Yu Liu, Kai-Rui Feng, Jia-Ying Zhao, Yu-Hui Wang*, Xiao-Di Yang*, Ping Tian*, and Guo-Qiang Lin. Synthesis of Decahydrocyclobuta[cd]indene Skeleton: Rhodium(III)-Catalyzed Hydroarylaton and Relay Thiophene-Promoted Intramolecular [2 + 2] Cycloaddition. Adv. Synth. Catal.2020, 362, 4384–4390 (IF=5.851)
7. Jun-Li Zhang#, Dingding Gao#, Yun-Xuan Tan, Cheng-Yu He, Pei-Ying Peng, Guo-Qiang Lin, Qing-Hua Li*, Ping Tian*. Rhodium(III)-Catalyzed Kinetic Resolution of Racemic 1,6-Dienes via Asymmetric Borylative Cyclization. Org. Lett. 2020, 22, 3661-3666. (IF=6.091)
8. Ming-Shun Mei#, Yu-Hui Wang#, Qing Hu, Qing-Hua Li,Da-Yu Shi, Dingding Gao,* Guangbo Ge,* Guo-Qiang Lin, and Ping Tian*.Enantioselective [3 + 2] Annulation of Isatin-Derived MBH-Carbonates and 3-Nitroindoles Enabled by a Bifunctional DMAP-Thiourea. Chem. Commun.2020, 56, 10718-10721 (IF=5.996)
9. Dingding Gao#, Huixia Dou#, Haixia Su#, Mingming Zhang#, Ting Wang, Qiufeng Liu, Haiyan Cai, Zhuo Yang, Weiliang Zhu*, Yechun Xu*, Heyao Wang*, Yingxia Li*. From Hit to Lead: Structure-based Discovery of Naphthalene-1-Sulfonamide Derivatives as Potent and Selective Inhibitors of Fatty Acid Binding Protein 4. Eur. J. Med. Chem., 2018, 154, 44-59. (IF=5.572)
10. Bingbing Zhang#, Jiami Liu#, Dingding Gao#, Xiaolin Yu, Jinlei Wang, Xinsheng, Lei*. A fluorine scan on the Zn2+-binding thiolate side chain of HDAC inhibitor largazole: Synthesis, biological evaluation, and molecular modeling. Eur. J. Med. Chem., 2019, 182, 111672. (IF=5.572)
11. Haiyan Cai#, Qiufeng Liu#, Dingding Gao#, Ting Wang, Tiantian Chen,Guirui Yan, Kaixian Chen, Yechun Xu*, Heyao Wang*, Yingxia Li*, Weiliang Zhu*. Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination. Eur. J. Med. Chem.2015, 90, 241 -250. (IF=5.572)
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