Ettelaie, Camille - University of Hull - Department of Biology / Biomedical Sciences

个人简介

Lecturer in Biomedical Sciences University of Hull 2001- present Plenary Lecturer in Haematology Hull York Med School 2003-present Lecturer in Biochemistry & Mol. Biology RF&UCMS, London 1999-2001 Senior Post–doctoral Research Assistant RFHSM, London 1997-1998 Post–doctoral Research Assistant RFHSM, London 1994-1997 Training PhD. in Biochemistry, King's College London 1993 MSc. (By research) in Biological Sciences, University of Salford 1987 BSc. Hons. in Biochemistry, University of Manchester 1984

研究领域

My research focuses on the function of the protein “Tissue Factor” (also known as CD142, thromboplasin or coagulation factor III). I am interested in the cellular processing and cellular functions of tissue factor in under normal and disease conditions.

近期论文

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Ettelaie C, Collier ME, Maraveyas A, Ettelaie R. Characterization of physical properties of tissue factor-containing microvesicles and a comparison of ultracentrifuge-based recovery procedures. Journal of Extracellular Vesicles 2014;3:23592 http://dx.doi.org/10.3402/jev.v3.23592 Collier ME, Maraveyas A, Ettelaie C. Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles. Thromb Haemost. 2014;111:647-655. doi: 10.1160/TH13-09-0769. Collier ME, Mah PM, Xiao Y, Maraveyas A, Ettelaie C. Microparticle-associated tissue factor is recycled by endothelial cells resulting in enhanced surface tissue factor activity. Thromb Haemost. 2013;110(5):966-976. doi: 10.1160/TH13-01-0055. Ettelaie C, Elkeeb AM, Maraveyas A, Collier ME. p38α phosphorylates serine 258 within the cytoplasmic domain of tissue factor and prevents its incorporation into cell-derived microparticles. Biochim Biophys Acta. 2013;1833(3):613-621. doi: 10.1016/j.bbamcr.2012.11.010. Collier, MEW, Ettelaie C. Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor. J. Biol. Chem. 286, 11977-11984 (2011) Collier, MEW, Ettelaie C. Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves ß1-integrin and extracellular signal regulated kinase activation. Arterioscler. Thromb. Vasc. Biol. 30, 1810-1817 (2010)