个人简介

University of York, B.Sc. 1985-1988, and D.Phil., Oct 1988-Oct 1991 University of Leicester, PDRA. Nov 1991-Dec 1993 University of Leeds, PDRA, Jan 1994-Sept 1995 University of Hull as Lecturer in Organic Chemistry, Sept 1995 – Sept 2011 University of Hull as Senior Lecturer since Oct 2011

研究领域

Biological Chemistry

Bioorganic/medicinal chemistry Organic synthesis Heterocyclic chemistry Novel amino acids and peptidomimetics Sporopollenin

近期论文

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Protein-free microcapsules obtained from plant spores as a model for drug delivery: ibuprofen encapsulation, release and tastes masking, A. Diego-Taboada, L. Maillet, J. Banoub, M. Lorch, A.S. Rigby, A.N. Boa, S.L. Atkin, and G. Mackenzie. J. Mater. Chem. B 2013, 1, 707-713. doi:10.1039/C2TB00228K Differential effect of fenamate analogues, econazole and 2-APB on TRPM2 channels, G.-L. Chen, B. Zeng, S. Eastmond, S. E. Elsenussi A. N. Boa, S.-Z. Xu, Brit. J. Pharmacol. 2012, 167, 1232-1243. doi: 10.1111/j.1476-5381.2012.02058.x Sequestration of edible oil from emulsions using new single and double layered microcapsules from plant spores, A. Diego-Taboada, P. Cousson, E. Raynaud, M. Lorch, S.L. Atkin, Y. Huang, A.N. Boa, S.T. Beckett, B.P. Binks, Y. Queneau, and G. Mackenzie. J. Mat. Chem 2012, 22, 9767-9773. doi:10.1039/C2JM00103A Effect of non-steroidal anti-inflammatory drugs and new fenamate analogues on TRPC4 and TRPC5 channels, H. Jiang, B. Zeng, G.-L. Chen, D. Bot, S. Eastmond, S. Elsenussi, S.L. Atkin, A.N. Boa and S.-Z. Xu, Biochem. Pharmacol. 2012, 83, 923-931. doi:10.1016/j.bcp.2012.01.014 Dimroth-type rearrangement of 1-benzyl and 1-glycosyl-5-aminoimidazoles to 4-N-substituted aminoimidazoles, S. Costanzi, S.P.N. Rouse, L. Vanbaelinghem, T.J. Prior, D.F. Ewing, A.N. Boa and G. Mackenzie, Tetrahedron Lett. 2012, 53, 412-415. doi:10.1016/j.tetlet.2011.11.058 A Synthesis of Bredinin (Mizoribine®) from an Acyclic Precursor, R.W. Humble, D.F. Middleton, J. Banoub, D.F. Ewing, A.N. Boa and G. Mackenzie, Tetrahedron Lett. 2011, 52 6223-6227. doi:10.1016/j.tetlet.2011.09.085 Sporopollenin capsules at fluid-interfaces: particle-stabilised emulsions and liquid marbles, B.P. Binks, A.N. Boa, M.A. Kibble, G. Mackenzie and A. Rocher, Soft Matter 2011, 7, 4017-4024. doi:10.1039/C0SM01516D TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids, L.R. Sadofsky, A.N. Boa, S.A. Maher, M.A. Birrell, M.G. Belvisi and A.H. Morice, Pharmacol. Res. 2011, 63, 30-36. doi:10.1016/j.phrs.2010.11.004 Access to a primary aminosporopollenin solid support from plant spores, S. Barrier, A. Lobbert, A. J. Boasman, A. N. Boa, M. Lorch, S. L. Atkin, and G. Mackenzie, Green Chemistry, 2010, 12, 234-40. doi: 10.1039/b913215e Synthesis and reactions of alpha-fluoro-alpha-amino amides, P. D. Bailey, A. N. Boa, and J. Clayson, Tetrahedron, 2009, 65, 1724-36. doi: 10.1016/j.tet.2008.11.061 Parallel kinetic resolution of racemic 1-phenylethanol using quasi-enantiomeric combinations of carboxylic acids mediated by N,N '-dicyclohexylcarbodiimide and 3,5-lutidine, N. Al Shaye, A. N. Boa, E. Coulbeck, and J. Eames, Tetrahedron Lett., 2008, 49, 4661-5. doi: 10.1016/j.tetlet.2008.05.036 Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase, T. Heikkila, C. Ramsey, M. Davies, C. Galtier, A. M. W. Stead, A. P. Johnson, C. W. G. Fishwick, A. N. Boa, and G. A. McConkey, J. Med. Chem., 2007, 50, 186-91. doi: 10.1021/jm060687j 1,3-dipolar cycloaddition reactions of benzo[b]thiophene 1,1-dioxide with azomethine ylides, N. Malatesti, A. N. Boa, S. Clark, and R. Westwood, Tetrahedron Lett., 2006, 47, 5139-42. doi: 10.1016/j.tetlet.2006.05.064 An efficient preparation of beta-dimethylaminovinyl sulfone and sulfoximide, and investigation of their reactivity as dipolarophiles, N. Pesa, C. J. Welch, and A. N. Boa, J. Heterocycl. Chem., 2005, 42, 599-607. doi: 10.1002/chin.200541032 Addition of (pyrazol-1-yl)acetyl and (pyridin-2-yl)acetyl groups to the terminal amino group of a Phe-Gly dipeptide affords ATCUN-Like copper(II) binding sites, A. N. Boa, J. D. Crane, R. M. Kowalczyk, and N. H. Sultana, Eur. J. Inorg. Chem., 2005, 872-8. doi: 10.1002/ejic.200400437 Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase, A. N. Boa, S. P. Canavan, P. R. Hirst, C. Ramsey, A. M. W. Stead, and G. A. McConkey, Biorg. Med. Chem., 2005, 13, 1945-67. doi: 10.1016/j.bmc.2005.01.017 (3,5-dimethylpyrazol-1-yl)acetic acid, A. N. Boa and J. D. Crane, Acta Crystallogr. Sect. E.-Struct Rep. Online, 2004, 60, O966-O7. doi: 10.1107/s1600536804010761 Thioglycosylated cationic porphyrins - convenient synthesis and photodynamic activity in vitro, S. Ahmed, E. Davoust, H. Savoie, A. N. Boa, and R. W. Boyle, Tetrahedron Lett., 2004, 45, 6045-7. doi: 10.1016/j.tetlet.2004.06.021 Ring opening reactions of quinoline substituted epoxides, A. N. Boa, S. Clark, P. R. Hirst, and R. Westwood, Tetrahedron Lett., 2003, 44, 9299-302. doi: 10.1016/j.tetlet.2003.10.062 On the sulfimidation of benzo[b]thiophene, S. J. Archibald, A. N. Boa, and N. Pesa, Chem. Commun., 2003, 1736-7. doi: 10.1039/b304696f