陈缙泉 - 华东师范大学 - 物理与电子科学学院

个人简介

陈缙泉，现任华东师范大学精密光谱科学与技术国家重点实验室教授。2003-2007年在南京大学进行了本科阶段的学习，后于2007-2012年在美国俄亥俄州立大学 (The Ohio State University) 取得博士学位。然后于2012-2013年在美国蒙大拿州立大学 (Montana State University) 和2013-2015年在埃默里大学 (Emory University) 进行了两阶段博士后研究工作。主要研究方向是高灵敏超快时间分辨手性光谱技术的发展和应用该技术研究分子体系中手性产生、放大的机理以及与分子激发态动力学过程的关联，近年来工作已在 Science, Journal of the American Chemical Society, Angewandte Chemie International Edition, Nature Communications, Chem等期刊发表，目前共发表论文130余篇。2016年入选国家青年海外高层次人才计划，2019年入选上海市青年科技启明星计划。目前担任上海市生物物理学会副理事长，《Chinese Journal of Chemical Physics》青年编委。教育经历 2007/08-2012/08，美国俄亥俄州立大学，博士 2003/09-2007/06，南京大学，学士工作经历 2015/10-至今，华东师范大学，精密光谱科学与技术国家重点实验室，教授 2013/09-2015/09，美国埃默里大学，博士后研究员，合作导师：Tianquan Lian 2012/08-2013/08，美国蒙大拿州立大学，博士后研究员, 合作导师：Bern Kohler

研究领域

激发态超快动力学，生物光子学, 生物传感, 生物探针, 生物成像, DNA损伤与修复, 飞秒激光光谱

近期论文

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Wang, X.; Wu, P.; Wang, Y.; Cui, T.; Jia, M.; He, X.; Wang, W.; Pan, H.; Sun, Z.; Yang, H.; Chen, J.*; Unraveling the Origin of Multichannel Circularly Polarized Luminescence in a Pyrene-Functionalized Topologically Chiral [2]Catenane, Angewandte Chemie International Edition, 2024, 63, e202407929. Yin, L.; Zhao, B.; Zhou, J.; Huang, Y.; Ma, H.; Zhou, T.; Mou, J.; Min, P.*; Chen, J.*; Ge, G.*; Qian, X.*; Luo, X.*; Yang, Y.*; A Carbon-Caged Rhodamine Generating Nitrosoperoxycarbonate for Photoimmunotherapy, Angewandte Chemie International Edition, 2024, 63, e202402949. Zhang, X.; Liu, M.; Hu, Y.; Wang, X.; Wei, R.; Yao, C.; Shi, C.; Qiu, Y.; Yang, T.; Luo, X.; Chen, J.*; Sun, W.*; Chen, H.*; Qian, X.*; Yang, Y.*; Albumin-Chaperoned Deep-NIR Triarylmethane Dyes for High-Contrast In Vivo Imaging and Photothermal Therapy, Advanced Materials, 2024, 2411515. Zhou, J.; Wang, X.; Jia, M.; He, X.; Pan, H.; Chen, J.*; Ultrafast spectroscopy study of DNA photophysics after proflavine intercalation, Journal of Chemical Physics, 2024, 160, 124305. Chen, Z.; Wang, X.*; Jia, M.; He, X.; Pan, H.; Chen, J.*; Ribose and Deoxyribose Group Alter Excited-State Dynamics of 5-Azacytosine in Solution, Photochemistry and Photobiology, 2024, 100, 291-297. Cui, T.; Jia, M.*; Wu, P.; Hu, K.; Wang, X.; Zhang, S.; Pan, H.; Chen, J.*; Development and Application of Ultrafast Circular Dichroism Spectroscopy Techniques, Chin. J. Chem. Phys. 2024, 37, 449-460. Wang, D.; Jia, M.; He, X.; Pan, H.; Chen, J.*; Methylation Induces a Low-energy Emissive State in N6-methyladenine Containing Dinucleotides, ChemPhotoChem, 2024, 8, e202300235. Hu, K.; He, X.*; Jin, P.; Wang, X.; Pan, H.; Chen, J.*; Unravelling the Competition between Internal Conversion and Intersystem Crossing in Twisted molecule 9-Phenylacridine by Femtosecond Time-resolved Spectroscopy, ChemPhotoChem, 2024, 8, e202400108. Jin, P.; Wang, X.*; Jia, M.; He, X.; Pan, H.; Chen, J.*; Ultrafast and Multichannel Generation of the Triplet State in DNA-Intercalated Gilvocarcin V for an Enhanced Photoaddition Reaction, Journal of Physical Chemistry Letters, 2024, 15, 2765-2771. Wang, X.; Martinez-Fernandez, L.; Zhang, Y.; Wu, P.; Kohler, B.*; Improta, R.*; Chen, J.*; Ultrafast Formation of a Delocalized Triplet-Excited State In an Epigenetically Modified DNA Duplex under Direct UV Excitation, Journal of the American Chemical Society, 2024, 146: 1839-1848. Wu, P.; Wang, X.*; Pan, H.; Chen, J.*; Wavelength dependent excited state dynamics observed in canonical pyrimidine nucleosides, Journal of Photochemistry and Photobiology, 2023, 18, 100211. Wang, D.; Wang, X.*; Jin, P.; Zhou, Y., Jia, M.; Pan, H.; Sun, Z.; Chen, J.*; Distinct doorway states lead to triplet excited state generation in epigenetic RNA nucleosides, Physical Chemistry Chemical Physics, 2023, 25: 15153–15161. Jin, X.; Guo, S.; Wang, X.; Cong, M.; Chen, J.*; Zhang, Z.*, Su, J.; Qu, D.; Tian, H.*; Sequential Multistep Excited-State Structural Transformations in N,N’-Diphenyl-dihydrodibenzo[a,c]phenazine Fluorophores, Angewandte Chemie International Edition, 2023, 62,e202305572. Han, Y.; Jia, Y.*; Wang, X.; Chen, Z.; Jin, P.; Jia, M.; Pan, H.; Sun, Z.; Chen, J.*; Ultrafast excited state dynamics of two non-emissive flavonoids that undergo excited state intramolecular proton transfer in solution, Chemical Physics Letters, 2023, 811: 140189. Jin, P.; Wang, J.; Wang, X.; Jia, M.; Pan, H.; Mei, Y.*, Chen, J.*; Tracking the Early Stage of Triplet-Induced Photodamage in a DNA Dimer and Oligomer Containing 5?Methylcytosine, Journal of Physical Chemistry B, 2023, 127(31): 6878-6886. Li, H.; Cao, S.; Zhang, S., Chen, J.*; Xu, J.*; Ultrafast proton coupled electron transfer between tryptophan and tyrosine in peptides Trp-Pron-Tyr, Chinese Journal of Chemical Physics, 2023, 36(4): 384-396. An, Q.; Xing, Y.; Pu, R.; Jia, M.; Chen, Y.; Hu, A.; Zhang, S.; Yu, N.; Du, J.; Zhang, Y.; Chen, J.*; Liu, W.*; Hong, X.*; Zuo, Z.*; Identification of Alkoxy Radicals as Hydrogen Atom Transfer Agents in Ce-Catalyzed C?H Functionalization, Journal of the American Chemical Society, 2023, 145: 359?376. Han, Y.; Wang, X.*; He, X.; Jia, M.; Pan, H.; Chen, J.*; Excited State Kinetics of Benzo[a]pyrene Is Affected by Oxygen and DNA, Molecules, 2023, 28, 5269. Zhou, J.; Jia, Y.*; Wang, X.; Jia, M.; Pan, H.; Sun, Z.; Chen, J.*; Excited-State Dynamics of Proflavine after Intercalation into DNA Duplex, Molecules, 2022, 27, 8157. Wu, P.; Wang, X.; Pan, H.; Chen, J.*; Direct Observation of Excitation Wavelength-Dependent Ultrafast Intersystem Crossing in Cytosine Nucleoside Solution, Journal of Physical Chemistry B, 2022, 126(40): 7975-7980. Wang, D.; Wang, X.*; Jiang, Y.; Cao, S.; Jin, P.; Pan, H.; Sun, H.; Sun, Z.; Chen, J.*; Excited State Dynamics of Methylated Guanosine Derivatives Revealed by Femtosecond Time-resolved Spectroscopy, Photochemistry and Photobiology, 2022, 98: 1008–1016. Chen, L.; Jiang, X.; Lv, M.; Wang, X.; Zhao, P.; Zhang, M.; Lv, G.; Wu, J.; Liu, Y.; Yang, Y.*; Chen, J.*; Bu, W.* Reductive-damage-induced intracellular maladaptation for cancer electronic interference therapy, Chem 2022, 8 (3), 866-879. Jin, P.; Wang, X.*; Pan, H.; Chen, J.* One order of magnitude increase of triplet state lifetime observed in deprotonated form selenium substituted uracil, Phys. Chem. Chem. Phys. 2022, 24, 875-882. Wang, Y.; Zhou, Q.; He, X.; Zhang, Y.; Tan, H.; Xu, J.; Wang, C.*; Wang, W.; Luo, X.; Chen, J.*, Xu, L.* Dithienylethene metallodendrimers with high photochromic efficiency, Chin. Chem. Lett. 2022, 33 (3), 1613-1618. Wang, X.; Martinez-Fernandez, L.; Zhang, Y.; Improta, R.*; Kohler, B.*; Xu, J.; Chen, J.* Solvent-dependent Stabilization of a Charge Transfer State is the Key to Ultrafast Triplet State Formation in an Epigenetic DNA Nucleoside, Chem. Eur. J. 2021, 27, 10932-10940. Liu, Y.; Pan, H.*; Xu, J.; Chen, J.* Long Chain Fatty Acid Affects Excited State Branching in Bilirubin-Human Serum Protein Complex, Chin. J. Chem. Phys. 2021, 34, 621-627. Lv, M.; Lu, X.; Jiang, Y.; Sandoval-Salinas, M.; Casanova, D.*; Sun, H.; Sun, Z.; Xu, J.; Yang, Y.; Chen, J.* Near-Unity Triplet Generation Promoted via Spiro-Conjugation. Angewandte Chemie International Edition 2021, 61 (4), e202113190 Lv, M.; Wang,X.; Wang,D.; Li, X.; Liu, Y.; Pan, H.; Zhang, S.; Xu, J.; Chen, J.* Unravel the Role of Charge Transfer State during Ultrafast Intersystem Crossing in Compact Organic Chromophores. Phys. Chem. Chem. Phys. 2021, 23, 25455-25466. Lv, M.; Wang, X.; Pan, H.; Chen, J.* Direct Observation of Ultrafast Access to a Solvent-Independent Singlet–Triplet Equilibrium State in Acridone Solutions. J. Phys. Chem. B 2021, 125, 13291–13297. Zhang, K.; Wang, F.; Jiang, Y.; Wang, X.; Pan, H.; Sun, Z.; Sun, H.; Xu, J.; Chen, J.* New Insights about the Photostability of DNA/RNA Bases: Triplet nπ* State Leads to Effective Intersystem Crossing in Pyrimidinones. J. Phys. Chem. B 2021, 125, 2042-2049. Xu, T.; Hu, Z.; Lv, M.; Zhou, Z.*; Xu, J.; Sun, Z.; Sun, H.; Chen, J.* Hydrogen Atom and Water Complex Determine the Excited State Dynamics of 8-Azaguanine. Chemical Physics 2021, 544, 111118 Lv, M.; Yu, Y.; Sandoval-Salinas, ME.; Xu, J.; Lei, Z.*; Casanova, D.*; Yang, Y.*; Chen, J.* Engineering Charge Transfer State to Facilitate Spin‐orbit Charge Transfer Intersystem Crossing in Spirobis [anthracene] diones Solution. Angewandte Chemie International Edition 2020, 59 (49), 22179-22184. Sun, L.; He, X.; Yuan, Y.; Chen, J.*; Zhan, W.; Wang, X.; Zhao, Y.*; Han, X.* Tuning Interfacial Sequence between Nitrogen-Doped Carbon Layer and Au Nanoparticles on Metal-Organic Framework-Derived TiO2 to Enhance Photocatalytic Hydrogen Production. Chemical Engineering Journal 2020, 397, 125468. Shen,J.; Chen, Z.; Han, S.; Zhang, H.; Xu, H.*; Xu, C.; Ding,Z.; Yuan, R.; Chen, J.*; Long, J.* Plasmonic Electrons‐Driven Solar‐to‐Hydrocarbon Conversion over Au NR@ ZnO Core‐Shell Nanostructures. ChemCatChem 2020, 12 (11), 2989-2994 Zhao, L.; Chen, Y.; Yu, X.; Xing, X.; Chen, J.*; Song, J.*; Qu, J. Low-threshold stimulated emission in perovskite quantum dots: single-exciton optical gain induced by surface plasmon polaritons at room temperature. Journal of Materials Chemistry C 2020, 8, 5847-5855. Liu, Y.; Chen, Z.; Wang, X.; Cao, S.; Xu, J.; Jimenez, R.*; Chen. J.* Ultrafast spectroscopy of biliverdin dimethyl ester in solution: pathways of excited-state depopulation. Physical Chemistry Chemical Physics2020, 22, 19903-19912. Fu, L.; Wang, Z.; Liu,Y.; Wang, X.; Xu, R.; Liu, W.*; Chen, J.*; Xu, J. Observation of Triplet nπ* State in Ultrafast Intersystem Crossing of 6-Azathymine. Journal of Photochemistry and Photobiology A: Chemistry 2020, 396, 112491. Xu, R.; Hu, Z.; Wang, X.; Liu, Y.; Zhou, Z.; Xu, J.; Sun, Z.; Sun, H.; Chen, J.* Intramolecular Charge Transfer in 5-Halogen Cytidines Revealed by Femtosecond Time-resolved Spectroscopy. J. Phys. Chem. B 2020, 124, 2560-2567. Chen, Z.; Liu, Y.; He, X.*; Chen, J.* Ultrafast excited state dynamics of biliverdin dimethyl Ester coordinate with zinc ions. Chinese Journal of Chemical Physics 2020,33 (1), 69-74. Cao, X.; Zhang, C.; Gao, Z.; Liu, Y.; Zhao, Y.; Yang, Y.; Chen, J.*; Jimenez, R.*; Xu, J. Ultrafast internal conversion dynamics of bilirubin bound to unag and its n57a mutant. Phys. Chem. Chem. Phys. 2019, 21, 2365-2371. Zhou, Z.; Wang, X.; Chen, J.*; Xu, J. Direct observation of intramolecular charge transfer state in epigenetic nucleobase n6-methyladenine. Phys. Chem. Chem. Phys.2019, 21, 6878-6885. Zhou, Z.; Hu, Z.; Zhang, X.; Jia, M.; Wang, X.; Su, H.; Sun, H.; Chen, J.*; Xu, J. pH controlled intersystem crossing and singlet oxygen generation of 8-azaadenine in aqueous solution. ChemPhysChem 2019, 20, 757-765. He, X.; Zhao, L.; Zhou, Z.; Zhang, S.; Pan, H.; Chen, J.*; Xu, J.* Near unity charge separation efficiency leads to pure ultraviolet emission in few layer graphene nanosheets. Nanotechnology 2019, 30, 295201. He, X.; Zhang, S.; Pan, H.; Chen, J.*; Xu, J.* Horizontally aggregation of monolayer reduced graphene oxide under deep uv irradiation in solution. Nanoscale Research Letters 2019, 14, 117. Wang, X.; Yu, Y.; Zhou, Z.; Liu, Y.; Yang, Y.; Xu, J.; Chen, J.* Ultrafast intersystem crossing in epigenetic DNA nucleoside 2′-deoxy-5-formylcytidine. J. Phys. Chem. B 2019, 123, 5782-5790.