郭兴伟 - 清华大学 - 基础分子科学中心

个人简介

Xingwei grew up at the foot of the Yanshan Mountains in Qinhuangdao and pursued his undergraduate studies at Hebei University of Technology. In 2007 he joined the group of Zhiping Li at Renmin University of China for his Master studies on iron-catalyzed radical reactions. In 2010 he went on to pursue his PhD in Physical Organic Chemistry from University (LMU) of Munich, Germany, under the supervision of Herbert Mayr, working on the kinetic and mechanistic studies of quinones. After graduating, he joined the group of Samir Z. Zard to study the radical chemistry of xanthates at École Polytechnique in France as a CNRS postdoctoral fellow (2014–2015). Then he moved to Oliver S. Wenger’s lab at the University of Basel in Switzerland as a NCCR postdoctoral fellow (2015–2019), where his work focused on photo-induced electron transfer and photocatalysis. In 2019 he started his independent career at Tsinghua University, where he is currently an Associate Professor of Chemistry.

研究领域

Radicals, i.e. molecules with an unpaired electron, are involved as short-lived intermediates in many chemical transformations. While radicals have already played an import role in organic synthesis and macromolecular chemistry for almost a century, recent decades have witnessed a hype in radical chemistry: Photocatalysis, organic electronics, atmospheric chemistry, and enzyme catalysis are just few examples of eminent current research activities. Electron Paramagnetic Resonance (EPR) is the most important method to investigate structure and reactivities of radicals. However, the presently available techniques either allow to detect radicals with high sensitivity (steady-state cw-EPR) or provide high time resolution. We have now developed a method, Ultrawide Single Sideband Phase-Sensitive Detection Time Resolved EPR (U-PSD TREPR), which combines both aspects and allows to detect radicals with an approximately two orders of magnitude higher sensitivity compared to conventional TREPR, without compromising time resolution. This new and universal method can be expected to open a new chapter in radical chemistry.

近期论文

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Direct Observation of All Open-Shell Intermediates in a Photo-catalytic Cycle Jianqing Qi‡, Weiqun Suo‡, Jing Liu, Songtao Sun, Lei Jiao*, Xingwei Guo*J. Am. Chem. Soc. 2024, 146, 7140–7145 Photoinduced Selective B–H Activation of nido-Carboranes Shengwen Xu, Hongjian Zhang, Jingkai Xu, Weiqun Suo, Changsheng Lu, Deshuang Tu*, Xingwei Guo*, Jordi Poater*, Miquel Solà*, Hong Yan*J. Am. Chem. Soc. 2024, 146, 7791–7802 Time-resolved electron paramagnetic resonance spectrometer based on ultrawide single-sideband phase-sensitive detection Shixue Zhang, Shengqi Zhou, Jianqing Qi, Lei Jiao, Xingwei Guo*Rev. Sci. Instrum. 2023, 94, 084101 Longevity gene responsible for robust blue organic materials employing thermally activated delayed fluorescence Qing-Yu Meng, Rui Wang, Yi-Lei Wang, Xing-Wei Guo, Yu-Qi Liu, Xue-Liang Wen, Cheng-Yu Yao, Juan Qiao*Nat. Commun. 2023, 14, 3927 Water-Soluble Tris(cyclometalated) Iridium(III) Complexes for Aqueous Electron and Energy Transfer Photochemistry Mirjam R. Schreier, Xingwei Guo, Björn Pfund, Yasunori Okamoto, Thomas R. Ward*, Christoph Kerzig*, Oliver S. Wenger* Acc. Chem. Res. 2022, 55, 1290–1300 Reductive Amination and Enantioselective Amine Synthesis by Photoredox Catalysis Xingwei Guo, Yasunori Okamoto, Mirjam R. Schreier, Thomas R. Ward*, Oliver S. Wenger* Eur. J. Org. Chem. 2020, 1288–1293 Photo-triggered hydrogen atom transfer from an iridium hydride complex to unactivated olefins Mirjam R. Schreier, Björn Pfund, Xingwei Guo*, Oliver S. Wenger*Chem. Sci. 2020, 11, 8582–8594 Shortcuts for Electron‐Transfer through the Secondary Structure of Helical Oligo‐1,2‐Naphthylenes Alessandro Castrogiovanni, Patrick Herr, Christopher B. Larsen, Xingwei Guo, Christof Sparr*, Oliver S. Wenger*Chem. Eur. J. 2019, 25, 16748–16754 Unexpected Hydrated Electron Source for Preparative Visible-Light Driven Photoredox Catalysis Christoph Kerzig*, Xingwei Guo, Oliver S. Wenger*J. Am. Chem. Soc. 2019, 141, 2122–2127 Electron Transfer across o-Phenylene Wires Sabine Malzkuhn, Xingwei Guo, Daniel Häussinger, Oliver S. Wenger*J. Phys. Chem. 2018, 123, 96–102 Mixed‐Valent Molecular Triple Deckers Hauke C. Schmidt, Xingwei Guo, Pascal U. Richard, Markus Neuburger, Cornelia G. Palivan*, Oliver S. Wenger*Angew. Chem. Int. Ed. 2018, 57, 11688–11691 Charge Accumulation and Multi‐Electron Photoredox Chemistry with a Sensitizer–Catalyst–Sensitizer Triad Julia Nomrowski, Xingwei Guo, Oliver S. Wenger*Chem. Eur. J. 2018, 24, 14084–14087 Reductive Amination by Photoredox Catalysis and Polarity‐Matched Hydrogen Atom Transfer Xingwei Guo*, Oliver S. Wenger*Angew. Chem. Int. Ed. 2018, 57, 2469–2473 Enantioselective synthesis of amines by combining photoredox and enzymatic catalysis in a cyclic reaction network Xingwei Guo, Yasunori Okamoto, Mirjam R. Schreier, Thomas R. Ward*, Oliver S. Wenger*Chem. Sci. 2018, 9, 5052–5056