李金波 - 南京大学 - 化学化工学院

个人简介

副教授，博士生导师。先后于2007年及2012年获得南京大学化学化工学院理学学士及博士学位，并于博士间在美国斯坦福大学医学院进行学习研究，2012-2017年在南京大学生命科学学院及化学化工学院进行研究工作，2017年起受聘南京大学化学化工学院副教授，主要研究方向为核酸化学生物学。现已在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、CCS Chem.、ACS Nano、Chem. Sci.、Chem. Soc. Rev.等期刊发表论文30余篇，申请发明专利5项，获得授权4项。主持或参与国家及省部级课题多项。

研究领域

核酸化学生物学：核酸化学修饰；生物大分子调控；肿瘤基因治疗

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Weishan Wang, Chenghong Zhu, Bin Zhang, Yi Feng, Yan Zhang,* Jinbo Li,* Self-Assembled Nano-PROTAC Enables Near-Infrared Photodynamic Proteolysis for Cancer Therapy. J. Am. Chem. Soc. 2023, 10.1021/jacs.3c04109. Yan Wang, Jingzi Zhang, Jiafang Deng, Chengzhi Wang, Lei Fang,* Yan Zhang,* Jinbo Li,* Targeted Degradation of DNA/RNA Binding Proteins via Covalent Hydrophobic Tagging. CCS Chem. 2023, 10.31635/ccschem.023.202302873. Chenghong Zhu, Weishan Wang, Yan Wang, Yan Zhang,* Jinbo Li,* Dendronized DNA Chimeras Harness Scavenger Receptors To Degrade Cell Membrane Proteins. Angew. Chem. Int. Ed. 2023, 62, e202300694. Gaigai Li, Yan Zhang,* Jinbo Li,* A hybrid nanoassembly for ultrasound-inducible cytosolic siRNA delivery and cancer sono-gene therapy. Ultrason. Sonochem. 2023, 92, 106262. Weishan Wang, Jiafang Deng, Yan Zhang,* Jinbo Li,* A Small-Molecule Probe with a Dual Function of miRNA Inhibition and Target identification. Chem. Eur. J. 2023, 29, e202202013. Xingxing Wang, Xiao Xiao, Yi Feng, Jinbo Li,* Yan Zhang,* A photoresponsive antibody-siRNA conjugate for activatable immunogene therapy of cancer. Chem. Sci. 2022, 13, 5345-5352. Xingxing Wang, Yan Wang, Ji Li, Tian Tian, Jinbo Li,* Zijian Guo,* Yan Zhang,* T Cell-Signaling-Responsive Conjugate of Antibody with siRNA to Overcome Acquired Resistance to anti-PD-1 Immunotherapy. Adv. Therap. 2022, 5, 2100161. Lei Chen, Gaigai Li, Xingxing Wang, Jinbo Li,* Yan Zhang,* Spherical Nucleic Acids for Near-Infrared Light-Responsive Self-Delivery of Small-Interfering RNA and Antisense Oligonucleotide. ACS Nano 2021, 15, 11929-11939. Jinbo Li, Hao Kong, Lei Huang, Bo Cheng, Ke Qin, Mengmeng Zheng, Zheng Yan, Yan Zhang,* Visible Light-Initiated Bioorthogonal Photoclick Cycloaddition. J. Am. Chem. Soc. 2018, 140, 14542-14546. Jinbo Li, Lei Huang, Xiao Xiao, Yingjie Chen, Xingxing Wang, Zhengquan Zhou, Chenyu Zhang,* Yan Zhang,* Photoclickable MicroRNA for the Intracellular Target Identification of MicroRNAs. J. Am. Chem. Soc. 2016, 138, 15943-15949.