王丹 - 北京师范大学-香港浸会大学

个人简介

教育背景香港城市大学计算机系博士香港城市大学电子及通讯系学士工作经历 (2017 - 2022) 生物信息副研究员, 新型基因编辑工具项目组组长, 深圳华大生命科学研究院 (2018 - 2022) 硕士生导师, 华大基因学院

研究领域

生物信息基因编辑宏基因组泛基因组染色体组重排

近期论文

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Wang D, Li S, Guo F, Ning K, Wang L. Core-genome scaffold comparison reveals the prevalence that inversion events are associated with pairs of inverted repeats[J].BMC genomics,2017,18(1): 1-13. Wang D, Li J, Wang L. Comprehensive study of instable regions in Pseudomonas aeruginosa and Mycobacterium tuberculosis[J]. Biomedical engineering online, 2018, 17(1): 1-14. Wang D, Wang L. GRSR: a tool for deriving genome rearrangement scenarios from multiple unichromosomal genome sequences[J]. BMC bioinformatics, 2018, 19(9): 11-19. Zou H*, Wang D*, Ren H*, Cai K, Chen P, Fang C, Shi Z, Zhang P, Wang J, Yang H, Zhong H. Effect of caloric restriction on BMI, gut microbiota, and blood amino acid levels in non-obese adults[J]. Nutrients, 2020, 12(3): 631. Peng Y*, Tang S*, Wang D*, Zhong H, Jia H, Cai X, Zhang Z, Xiao M, Yang H, Wang J, Kristiansen K, Xu X, Li J. MetaPGN: a pipeline for construction and graphical visualization of annotated pangenome networks[J]. GigaScience, 2018, 7(11): giy121. Huang L, Zhang D, Dai X, Sun H, Ji Z, Liu C, Gong Y, Li A, Li B, Shen X, Qi C, Jiang Y*, Chen T*, Wang D*. Off-detector: a platform to accurately identify, annotate and share editing-induced mutations from genome editing assays. Genomics, Proteomics & Bioinformatics. (under revision). Li Z*, Wang X*, Xu D*, Zhang D*, Wang D, Dai X, Wang Q, Li Z, Gu Y, Ouyang W, Zhao S, Huang B, Gong J, Zhao J, Chen A, Shen Y, Dong Y, Zhang W, Xu X, Xu Chong, Jiang Y. DNB-based on-chip motif finding: A high-throughput method to profile different types of protein-DNA interactions[J]. Science advances, 2020, 6(31): eabb3350 Guo F, Wang D, Wang L. Progressive approach for SNP calling and haplotype assembly using single molecular sequencing data[J]. Bioinformatics, 2018, 34(12): 2012-2018. Zhang X, Zhong H, Li Y, Shi Z, Ren H, Zhang Z, Zhou X, Tang S, Han X, Lin Y, Yang F, Wang D, Fang C, Fu Z, Wang L, Zhu S, Hou Y, Xu X, Yang H, Wang J, Kristiansen K, Li J, Ji L. Sex-and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities[J]. Nature Aging, 2021, 1(1): 87-100. Liu X, Tang S, Zhong H, Tong X, Jie Z, Ding Q, Wang D, Guo R, Xiao L, Xu X, Yang H, Wang J, Zong Y, Liu W, Liu X, Zhang Y, Brix S, Kristiansen K, Hou Y, Jia H, Zhang T. A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases[J]. Cell discovery, 2021, 7(1): 1-15. Chen Z Z, Lin G, Wang L, Chen Y, Wang D. Approximation algorithms for the maximum weight internal spanning tree problem[J]. Algorithmica, 2019, 81(11): 4167-4199. Guo F, Zou Q, Yang G, Wang D. Identifying protein-protein interface via a novel multi-scale local sequence and structural representation[J]. BMC bioinformatics, 2019, 20(15): 1-11. Song W, Sun H X, Zhang C, Cheng L, Peng Y, Deng Z, Wang D, Wang Y, Hu M, Liu W, Yang H, Shen Y, Li J, You L, Xiao M. Prophage Hunter: an integrative hunting tool for active prophages[J]. Nucleic acids research, 2019, 47(W1): W74-W80. Gao Q, Ouyang W, Kang B, Han X, Xiong Y, Ding R, Li Y, Wang F, Huang L, Chen L, Wang D, Dong X, Zhang Z, Li Y, Ze B, Hou Y, Yang H, Ma Y, Gu Y, Chao C. Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression[J]. Theranostics, 2020, 10(11): 5137. Jie Z, Liang S, Ding Q, Li F, Tang S, Wang D, ... & Xu X. (2021). A transomic cohort as a reference point for promoting a healthy human gut microbiome. Medicine in Microecology, 100039. Wang Z, Kang B, Gao Q, Huang L, Fan Y, Yu J, Jiang B, Gao F, Wang D,... & Su X (2021). Quadruple-editing of MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells. Cancer Science.