个人简介
蔡宗苇教授1982年在厦门大学化学系获得学士学位,1990年在德国University of Marburg获得博士学位,1991-2000年分别在美国的大学和药物公司工作,2001年起受聘于香港浸会大学,现为化学系郭一伟冠名讲座教授,同时担任环境与生物分析国家重点实验室主任。蔡教授是英国皇家化学会会士,欧洲科学院外籍院士。
蔡宗苇教授从事质谱化学分析的基础理论及其在环境、生物、药物和痕量有机污染物的应用研究,目前主要研究与环境污染物相关的人体健康和疾病,已在国际专业刊物上发表500多篇论文。曾获国家自然科学二等奖(2011,排名第五),中国分析测试协会科学技术奖一等奖(2016)和特等奖(2020),教育部高等学校科学研究优秀成果奖自然科学奖二等奖(2018),亚太(国际)产学研促进会消除持久性有机污染物杰出贡献奖(2018),中国环境科学学会“消除持久性有机污染物杰出贡献奖”(2018)。蔡教授长期致力社会工作,现任中国毒理学会分析毒理专业委员会副主任委员、中国毒理学会环境毒理会副理事长、香港学者协会秘书长等职务。
近期论文
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Xiaojian Shao, Hailei Zhang, Zhu Yang, Huan Zhong, Yiji Xia and Zongwei Cai, “NAD tagSeq for transcriptome-wide identification and characterization of NAD+-capped RNAs”, Nat. Protoc.,15, 2813-2836 (2020).
Li Xiang, Lin Zhu, Yu Huang, and Zongwei Cai, “Application of Derivatization in Fatty Acids and Fatty Acyls Detection: Mass Spectrometry-Based Targeted Lipidomics”, Small Methods, doi: 10.1002/smtd.202000160 (2020).
Chao Zhao, Peisi Xie, Ting Yong, Wei Huang, Jianjun Liu, Desheng Wu, Fenfen Ji, Min Li, Doudou Zhang, Ruijin Li, Chuan Dong, Juan Ma, Zheng Dong, Sijin Liu, Zongwei Cai, “Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy”, Sci. Bull., doi: 10.1016/j.scib.2020.08.036 (2020).
Peisi Xie, Xiaoping Liang, Yuanyuan Song, and Zongwei Cai, “Mass Spectrometry Imaging Combined with Metabolomics Revealing the Proliferative Effect of Environmental Pollutants on Multicellular Tumor Spheroids”, Anal. Chem., 92, 11341-11348 (2020).
Peisi Xie, Chao Zhao, Xiaoping Liang, Wei Huang, Yanyan Chen, and Zongwei Cai, “Preparation of Frozen Sections of Multicellular Tumor Spheroids Coated with Ice for Mass Spectrometry Imaging”, Anal. Chem., 92, 7413–7418 (2020).
Xiaojian Shao, Hailei Zhang, Zhu Yang, Lin Zhu, Zongwei Cai, “Quantitative profiling of protein-derived electrophilic cofactors in bacterial cells with a hydrazine-derived probe”, Anal. Chem., 92, 4484-4490 (2020).
Jingchun Shi, Caihong Xu, Li Xiang, Jianmin Chen, and Zongwei Cai, “Tris(2,4-di-tert-butylphenyl)phosphate: An Unexpected Abundant Toxic Pollutant Found in PM2.5”, Environ. Sci. Technol., 54, 10570-10576 (2020).
Hongzhi Zhao, Yuanyuan Zheng, Lin Zhu, Li Xiang, Yanqiu Zhou, Jiufeng Li, Jing Fang, Shunqing Xu, Wei Xia, and Zongwei Cai, “Paraben Exposure Related To Purine Metabolism and Other Pathways Revealed by Mass Spectrometry-Based Metabolomics”, Environ. Sci. Technol., 54, 3447-3454 (2020).
Chao Zhao, Zhi Tang, Peisi Xie, Kaili Lin, Arthur Chi Kong Chung, Zongwei Cai, “Immunotoxic Potential of Bisphenol F Mediated through Lipid Signaling Pathways on Macrophages”, Environ. Sci. Technol., 53, 11420-11428 (2019).
Hongna Zhang, Xiaojian Shao, Hongzhi Zhao, Xiaona Li, Juntong Wei, Chunxue Yang, Zongwei Cai, “Integration of Metabolomics and Lipidomics Reveals Metabolic Mechanisms of Triclosan-Induced Toxicity in Human Hepatocytes”, Environ. Sci. Technol., 53, 5406–5415 (2019).
Hailei Zhang, Huan Zhong, Shoudong Zhang, Xiaojian Shao, Min Ni, Zongwei Cai, Xuemei Chen, Yiji Xia, “NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of proteincoding genes in Arabidopsis”, Proc. Natl. Acad. Sci., 116, 12072-12077 (2019).
Chao Zhao, Peisi Xie, Ting Yong, Hailin Wang, Arthur Chi Kong Chung, Zongwei Cai, “MALDI-MS Imaging Reveals Asymmetric Spatial Distribution of Lipid Metabolites from Bisphenol S-Induced Nephrotoxicity”, Anal. Chem., 90, 3196-3204 (2018).