Bolm, Carsten - RWTH Aachen University - Department of Chemistry

个人简介

03/1960 born in Braunschweig, Germany 1978 - 1984 TH Braunschweig (undergraduate studies in chemistry) 1983 - 1984 University of Wisconsin, Madison, USA 09/1984 Graduation: 'Master of Science, Chemistry' (University of Wisconsin, Madison, USA; Prof. Dr. H.-J. Reich) 12/1984 Graduation: 'Diplom-Chemiker-Hauptprüfung' (TH Braunschweig, Germany; Prof. Dr. H. Hopf) 1985 - 1987 Doctoral work at the Philipps-Universität Marburg, Germany 07/1987 Graduation: 'Dr. rer. nat.' (Philipps-Universität Marburg, Germany; Prof. Dr. M. T. Reetz) 1987 - 1988 Postdoctoral studies (M.I.T., Cambridge, USA; Prof. Dr. K. B. Sharpless) 1988 - 1993 Habilitation (TU Darmstadt, Germany, and Universität Basel, Switzerland; with Prof. Dr. B. Giese) 1993 Offers for C3-faculty positions at the Universities in Würzburg (declined), Hannover (declined), and Marburg 10/1993 Associate Professor of Organic Chemistry at the Philipps-Universität Marburg, Germany 03/1996 Chair and Full Professor of Organic Chemistry at the RWTH Aachen University, Germany (C4) 02/2000 Offer for a Chair and Full Professorship at the University in Freiburg, Germany (declined) 08/2005 Offer for a Chair and Full Professorship at the Ruprecht-Karls University in Heidelberg, Germany (declined) 04/2006 W3 Professor (Chair and Full Professorship) at the RWTH Aachen University, Germany 10/2012 Adjunct Professor at Wuhan Institute of Technology, Wuhan, China 10/2016 Honorary Professor at Central China Normal University, Wuhan, China

研究领域

Enantioselective catalysis Asymmetric synthesis Bioactive compounds Mechanochemistry Biomass Conversion Sulfur and fluorine chemistry

近期论文

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Sulfoximines from a Medicinal Chemist’s Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery M. Frings, C. Bolm, A. Blum, C. Gnamm, Eur. J. Med. Chem. 2017, 126, 225 - 245. Altering Product Selectivity by Mechanochemistry J. G. Hernández, C. Bolm, J. Org. Chem. 2017, 82, 4007 - 4019. Access to N-Cyanosulfoximines by Transition Metal-Free Iminations of Sulfoxides C. A. Dannenberg, L. Fritze, F. Krauskopf, C. Bolm, Org. Biomol. Chem. 2017, 15, 1086 - 1090. Rhodium(III)-Catalyzed Annulation of N-Methoxybenzamides with Heterobicyclic Alkenes by C–H Functionalization: Synthesis of Benzo[b]phenanthridinones Y. Cheng, K. Parthasarathy, C. Bolm, Eur. J. Org. Chem. 2017, 1203 - 1206. Mechanochemical Lignin-Mediated Strecker Reaction S. Dabral, M. Turberg, A. Wanninger, C. Bolm, J. G. Hernández, Molecules 2017, 22, 146. Rhodium(III)-Catalyzed Ortho Halogenations of N-Acylsulfoximines and Synthetic Applications toward Functionalized Sulfoximine Derivatives Y. Cheng, W. Dong, K. Parthasarathy, C. Bolm, Org. Lett. 2017, 19, 726 - 729. 1,2-Benzothiazines from Sulfoximines and Allyl Methyl Carbonate by Rhodium-Catalyzed Cross-Coupling and Oxidative Cyclization J. Wen, D. P. Tiwari, C. Bolm, Org. Lett. 2017, 19, 1706 - 1709. Mechanochemical Indole Synthesis by Rhodium-Catalysed Oxidative Coupling of Acetanilides and Alkynes under Solventless Conditions in a Ball Mill G. N. Hermann, C. L. Jung, C. Bolm, Green Chem. 2017, 19, 2520 - 2523. Mechanoenzymatic peptide and amide bond formation J. G. Hernández, K. J. Ardila-Fierro, D. Crawford, S. L. James, C. Bolm, Green Chem. 2017, 19, 2620 - 2625. Sulfoximines as ATR inhibitors: Analogs of VE-821 C. M. M. Hendriks, J. Hartkamp, S. Wiezorek, A.-D. Steinkamp, G. Rossetti, B. Lüscher, C. Bolm, Bioorg. Med. Chem. Lett. 2017, 27, 2659 - 2662. Mechanochemical Rhodium(III)-Catalyzed C–H Bond Amidation of Arenes with Dioxazolones under Solventless Conditions in a Ball Mill G. N. Hermann, C. Bolm, ACS Catal. 2017, 7, 4592 - 4596. Design, Synthesis and Evaluation of N-(tert-butyl)-Alanine-Derived Chiral Ligands; Aspects of Reactivity and Diastereoselectivity in the Reactions with α-Amino Acids M. Bremerich, C. Bolm, G. Raabe, V. Soloshonok, Eur. J. Org. Chem. 2017, 3211 - 3221. Organocatalytic Chemoselective Primary Alcohol Oxidation and Subsequent Cleavage of Lignin Model Compounds and Lignin S. Dabral, J. G. Hernández, P. C. J. Kamer, C. Bolm, ChemSusChem 2017, 10, 2707 - 2713. Dibenzothiophene Sulfoximine as NH3 Surrogate in the Synthesis of Primary Amines by Copper-Catalyzed C–X and C–H Bond Amination Z. Li, H. Yu, C. Bolm, Angew. Chem. 2017, 129, 9660 - 9663; Angew. Chem. Int. Ed. 2017, 56, 9532 - 9535. Synthesis of N-Propargylsulfoximines by Copper-Catalyzed A3-Couplings H. Cheng, J. Wen, C. Bolm, Chem. Eur. J. 2017, DOI: 10.1002/chem.201700953. Rhodium-catalyzed Synthesis of 1-(Acylamino)isoquinolines through Direct Annulative Coupling of 3-Aryl-1,2,4-oxadiazoles with Alkynes Y. Nishii, A.-K. Bachon, S. Moon, C. Bolm, M. Miura, Chem. Lett. 2017, DOI: 10.1246/cl.170536. Sulfoximidoyl-Containing Hypervalent Iodine(III) Reagents: 1-Sulfoximidoyl-1,2-benziodoxoles H. Wang, D. Zhang, H. Sheng, C. Bolm, J. Org. Chem. 2017, DOI: 10.1021/acs.joc.7b01535. Organic Dye-Catalyzed Atom Transfer Radical Addition–Elimination (ATRE) Reaction for the Synthesis of Perfluoroalkylated Alkenes D. P. Tiwari, S. Dabral, J. Wen, J. Wiesenthal, S. Terhorst, C. Bolm, Org. Lett. 2017, DOI: 10.1021/acs.orglett.7b01952.