个人简介
1981年大学毕业于桂林医学院药学系,1989年硕士毕业于黑龙江中医药大学中药系,1998年博士毕业于浙江大学化学系,2000年中国科学院上海药物研究所博士后出站留所工作至今。
研究领域
1.中药及复方药效物质研究;
2.中药体内药效物质发现方法学研究;
3.创新中药开发。
近期论文
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1.Xiaoting Tian, Zhixiong Li, Yunfei Lin, Mingcang Chen, Guoyu Pan, Chenggang Huang*, Study on the PK profiles of magnoflorine and its potential interaction in Cortex phellodendri decoction by LC-MS/MS, Analytical and Bioanalytical Chemistry, 406(3), 841-849, 2014
2.Peng Qi, Feng Zhang, Rui Xue, Zhixiong Li, Mingcang Chen, Zhaolin Sun, Chenggang Huang*, Identification of multiple constituents fromseed of Vaccaria segetalis with an adsorbents-separation strategy based on liquid chromatography coupled to quadrupole time-of-flight mass spectrometry, Rapid Communications in Mass Spectrometry, 28(11), 1243-1257, 2014
3.Yun Ling, Zhixiong Li, Mingcang Chen, Zhaolin Sun, Mingsong Fan, Chenggang Huang*, Analysis and detection of the chemical constituents of Radix Polygalae and their metabolites in rats after oral administration by ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 85, 1-13, 2013
4.Peng Qi, Zhixiong Li, Mingcang Chen, Zhaolin Sun, Chenggang Huang*, Metabolism and tissue distribution study of Vaccaria seeds (Wang-Bu-Liu-Xing) in benign prostatic hyperplasia model rat: Toward an in-depth study for its bioactive components, Journal of Pharmaceutical and Biomedical Analysis, 85, 218–230, 2013
5.Huihui Liu, Bin Wu, Guoyu Pan, Lei He, Zhixiong Li, Mingsong Fan, Longhai Jian, Mingcang Chen, Ke Wang, Chenggang Huang*, Metabolism and pharmacokinetics of mangiferin in conventional rats, pseudo-germ-free rats, and streptozo-tocin-induced diabetic rats, Drug Metabolism and Disposition, 40, 2109-2118, 2012
6.Yi Hong Tang, Zhao Lin Sun, Ming Song Fan, Zhi Xiong Li, Chenggang Huang*, Anti-Diabetic Effects of Tong Guan Wan, a Chinese Traditional Herbal Formula, in C57BL/KSJ-db/db Mice, Planta Medica, 78(1), 18-23, 2012
7.Luying Chen, Zhixiong Li, Yihong Tang, Xiaolan Cui, Ronghua Luo, Shanshan Guo, Yongtang Zheng, Chenggang Huang*, Isolation, identification and antiviral activities of metabolites of calycosin-7-O-β-D-glucopyranoside, Journal of Pharmaceutical and Biomedical Analysis, 56, 382-389, 2011
8.Huihui Liu, Ke Wang, Yihong Tang, Zhaolin Sun, Longhai Jian, Zhixiong Li, Bin Wu, Chenggang Huang*, Structure elucidation of in vivoand in vitro metabolites of mangiferin, Journal of Pharmaceutical and Biomedical Analysis, 55, 1075-1082, 2011
9.Quanbao Gu, Huiming Du, Chunhui Ma, Heike Fotis, Bin Wu, Chenggang Huang*, Wolfgang Schwarz*, Effects of α-asarone on the glutamate transporter EAAC1 in Xenopus oocytes, Planta Medica, 76(6),595-598, 2010
10.Guan Ye , Yihong Tang, Guiyun Wang, Zhixiong Li, Haiyan Zhu, Chunhui Ma, Zhaolin Sun, Chenggang Huang*, Characterization of the Multiple Absorbed Constituents in Rats after Oral Administration of Chai-Huang Decoction by Liquid Chromatography Coupled with Electrospray-Ionization Mass Spectrometry, Chemistry & Biodiversity, 7(12), 2917-2930, 2010