郭跃伟 - 中国科学院上海药物研究所 -

个人简介

教育经历 07/01/1978 - 07/01/1982 北京中医药大学中药学院，学士 07/01/1985 - 07/01/1988 中国药科大学/南京药物研究所，硕士 01/01/1994/ - 09/01/1997 意大利那不勒斯大学药学院/意大利国家科学院生物活性分子化学研究所，博士 10/01/1997 - 02/01/2000 意科院生物活性分子化学研究所，博士后 06/01/2000 - 02/01/2001 日本北海道大学药学院，研究员工作经历 07/01/1982 – 07/01/1985 山西医科大学药学系，助教 09/01/1988 – 12/01/1993 南京药物研究所，助研 01/01/1994 – 02/01/2000 意科院生物活性分子化学研究所/意大利那不勒斯大学药学院，访问学者、博士、博士后 02/01/2000 – 07/01/2000 中科院上海药物研究所，研究员 06/01/2000 – 02/01/2001 日本北海道大学药学院，研究员 02/01/2000 - 至今中科院上海药物研究所（2级研究员），所学位委员会副主任，上海药物所烟台分所副所长

研究领域

1.海洋生物和药用植物中生物活性成分的化学研究 2.海洋后鳃亚纲软体生物及其食源生物的化学及化学生态学研究

近期论文

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1. Jiang CS, Mueller W, Schroder C, Guo YW*. Disulfide- and multisulfide-containing metabolites from marine organisms. Chem Rev 2012; 112: 2179-2207. 2. Cai YS, Guo YW*, Khron K. Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes. Nat Prod Rep 2010; 27: 1840-1870. 3. Liang LF, Kurtán T, Mándi A, Yao LG, Li J, Zhang W, Guo YW*. Unprecedented diterpenoids as a PTP1B inhibitor from Hainan soft coral Sarcophyton trocheliophorum Marenzeller. Org Lett 2013; 15: 274-277. 4. Chen XL, Liu HL, Li J, Xin GR, Guo YW*. Paracaseolide A, first r-alkylbutenolide dimer with an unusual tetraquinane oxa-cage bislactone skeleton from Chinese mangrove Sonneratia paracaseolaris. Org Lett 2011; 13: 5032-5035. 5. Manzo E, Carbone M, Mollo E, Irace C, Di Pascale A, Li Y, Ciavatta ML, Cimino G, Guo YW*, Gavagnin M*. Structure and synthesis of a unique isonitrile lipid isolated from the marine mollusk Actinocyclus papillatus. Org Lett 2011; 13: 1897-1899. 6. Carbone M, Li Y, Irace C, Mollo E, Castelluccio F, Di Pascale A, Cimino G, Santamaria R, Guo YW*, Gavagnin M*. Structrue and cytotoxicity of phidianidines A and B: first finding of 1,2,4-oxadiazole system in a marine natural product. Org Lett 2011; 13: 2516-2519. 7. Jia R, Yan XH, Zhang W, Guo YW*. Bislatumlides C-F, further biscembranes from the Hainan soft coral Sarcophyton latum. J Org Chem 2013; 78: 3113-3119. 8. Cai YS, Kurtán T, Miao ZH, Mándi A, Komáromi I, Liu HL, Ding J, Guo YW*. Palmarumycins BG1–BG7 and preussomerin BG1, and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra. J Org Chem 2011; 76: 1821-1828. 9. Wang JR, Liu HL, Kurtán T, Mándi A, Antus S, Li J, Zhang HY, Guo YW*. Protolimonoids and norlimonoids from the stem bark of Toona ciliata var. pubescens. Org Biomol Chem 2011; 9: 7685-7696. 10. Wang JR, Carbone M, Gavagnin M, Mándi A, Antus S, Yao LG, Cimino G, Kurtán T, Guo YW*. Assignment of absolute configuration of bis--pyrone polypropionates from marine pulmonate molluscs. Eur J Org Chem 2012; 1107-1111. 11. Wang JR, Kurtán T, Mándi A, Guo YW*. Structures and absolute stereochemistries of nortriterpenoids from Schisandra chinensis (Turcz.) Baill. Eur J Org Chem 2012; 5471-5482. 12. Kurtán T, Jia R, Li Y, Pescitelli G, Guo YW*. Absolute configuration of highly flexible natural products by the solid-state ECD/TDDFT method: ximaolides and sinulaparvalides. Eur J Org Chem 2012; 6722-6728. 13. Carbone M, Ciavatta ML, Wang JR, Cirillo I, Mathieu V, Kiss R, Mollo E, Guo YW*, Gavagnin M*. Extending the record of bis-γ-pyrone polypropionates from marine pulmonate mollusks. J Nat Prod 2013; 76: 2065-2073. 14. Huang XY, Wang Q, Liu HL, Zhang Y, Xin GR, Shen X, Dong ML, Guo YW*. New diastereoisomeric macrocyclic polydisulfides from the mangrove Bruguiera gymnorrhiza. Phytochemistry 2009; 70: 2096-2100.

学术兼职

国际刊物“Marine Drugs”，“The Open Organic Chemistry Journal”，“Natural Product Science”，“Frontiers in Pharcology of Natural Products”和国内刊物“药学学报”，“中国天然药物”，“中国中药杂志”，“天然产物研究与开发”，“国际药学研究杂志”，“应用与环境生物学报”编委；中国药学会海洋药物专业委员会副主任委员；中科院南海海洋所、上海交通大学、合肥工业大学、江苏科技大学、山西大学客座教授。