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1. Ting Wang, Peng Sun, Liang Chen, Qi Huang, Kaixian Chen, Qi Jia, Yiming Li,* Heyao Wang*. Cinnamtannin D-1 protects pancreatic β-cells from palmitic acid-induced apoptosis by attenuating oxidative stress. Journal of Agricultural and Food Chemistry. 62 (2014):5038-5045
2. Lin-Fu Liang, Ting Wang, You-Sheng Cai, Wen-Fei He, Peng Sun, Yu-Fen Li, Qi Huang, Orazio Taglialatela-Scafati*, He-Yao Wang*, Yue-Wei Guo*. Brominated polyunsaturated lipids from the Chinese sponge Xestospongia testudinaria as a new class of pancreatic lipase inhibitors. European Journal of Medicinal Chemistry. 79(2014):290-297
3. Jia Liu, Xiu-Feng He, Gai-Hong Wang, Emilio F. Merino, Sheng-Ping Yang,Rong-Xiu Zhu,Li-She Gan, Hua Zhang, Maria B. Cassera, He-Yao Wang, David G. I. Kingston, and Jian-Min Yue*. Aphadilactones A−D, Four Diterpenoid Dimers with DGAT Inhibitory and Antimalarial Activities from a Meliaceae Plant. The Journal of Organic Chemistry. 79(2014):599−607
4. Bo Li, Gaihong Wang, Zhijian Xu, Yong Zhang, Xiangui Huang, Bubing Zeng, Kaixian Chen, Jiye Shi*, Heyao Wang*, Weiliang Zhu*. Discovery of N-substituted 3-arylisoquinolone derivatives as antitumor agents originating from O-substituted 3-arylisoquinolines via [2,3] or [3,3] rearrangement. European Journal of Medicinal Chemistry. 77 (2014):204-210
5. Haiyan Cai，Ting Wang, Jian-chun Zhao, Peng Sun, Gui-rui Yan, Hai-peng Ding, Ying-xia Li, He-yao Wang*,Wei-liang Zhu*, Kai-xian Chen. Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice. Acta Pharmacologica Sinica. 34(2013): 1397–1402
6. Bo Li, Gaihong Wang, Mu Yang, Zhijian Xu, Bubing Zeng,*, Heyao Wang*, Jingshan Shen, Kaixian Chen, Weiliang Zhu*.Overman rearrangement and PomeranzeFritsch reaction for the synthesis of benzoazepinoisoquinolones to discover novel antitumor agents. European Journal of Medicinal Chemistry. 70(2013):677-684
7. Guirui Yan, Jingjie Zhu, Laibin Zhang, Zhijian Xu, Gaihong Wang,Weiliang Zhu, Aijun Hou, HeyaoWang*. Dodoviscin A Inhibits Melanogenesis in Mouse B16-F10 Melanoma Cells. Planta Medica. 79(2013):933-938
8. Peng Sun, Ting Wang, Yuren Zhou, Hong Liu, Hualiang Jiang, Weiliang Zhu*, Heyao Wang*. DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic β-Cells Dysfunction in db/db Mice. PLOS ONE. 8 (6) (2013):e66744
9. Liang Chen, Peng Sun, Ting Wang, Kaixian Chen, Qi Jia,*, Heyao Wang,* and Yiming Li* Diverse Mechanisms of Antidiabetic Effects of the Different Procyanidin Oligomer Types of Two Different Cinnamon Species on db/db Mice. Journal of Agricultural and Food Chemistry. 60(36) (2012):9144-9150
10. Zhijian Xu, Guirui Yan, Gaihong Wang, Bo Li, Jianming Zhu, Peng Sun, Xiaodong Zhang, Cheng Luo, Heyao Wang*, Weiliang Zhu*. Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-RafV600E inhibitors. Biooranic Medicinal Chemistry Letters. 22(17) (2012):5428-5437
11. Hai-yan CAI, Zhi-jian XU, Jie TANG, Ying SUN, Kai-xian CHEN, He-yao WANG*, Wei-liang ZHU*. The essential role for aromatic cluster in the β3 adrenergic receptor. Acta Pharmacologica Sinica. 33(2012):1062–1068
12. Xiaodong Zhang, Jun Ji, Gurui Yan, Jinwei Wu, Xiaoyun Sun, Jingshan Shen, Hualiang Jiang, Heyao Wang. PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells. Journal of Cellular Biochemistry. 113(2012):2738-2743
13. Jinwei Wu, Peng Sun, Xiaodong Zhang, Hong Liu, Hualiang Jiang, Weiliang Zhu, Heyao Wang*. Inhibition of GPR40 protects MIN6 β-cells from palmitate-induced ER stress and apoptosis. Journal of Cellular Biochemistry. 113(2012):1152-1158
14. Xiao Hu, Jinwei Wu, Xiaodong Zhang, Qinshi Zhao, Jianming Huang, Heyao Wang*, Aijun Hou*. Isoprenylated Flavonoids and Adipogenesis-Promoting Constituents from Morus nigra. Journal of Natural Products. 74(4) (2011):816-824
15. Liangcai Zhao, Xiaodong Zhang, Heyao Wang*, Donghai Lin*. ¹H NMR-based metabonomic analysis of metabolic changes of serum and liver in Zucker obese rats. Analytical Letters 44(2011):1579–1590
16. Xiao-dong Zhang Jian-wei Yan, Gui-rui Yan Xiao-yun Sun, Jun Ji, Yi-ming Li, You-hong Hu*, He-yao Wang*. Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice. Acta Pharmacologica Sinica. 31 (2010):1470–1477
17. Xiaodong Zhang, Guirui Yan, Yiming Li,Weiliang Zhu*, Heyao Wang*, DC260126, a small molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats. Biomedicine & Pharmacotherapy. 64(9) (2010):647-651
18. Xiaodong Zhang, Jun Ji, Gurui Yan, Jinwei Wu, Xiaoyun Sun, Jingshan Shen, Hualiang Jiang, Heyao Wang*. Sildenafil promotes adipogenesis through a PKG pathway. Biochemical and Biophysical Research Communications. 396 (2010):1054-1059
19. Haiyan Cai, Gurui Yan, Xiaodong Zhang, Gorbenko O, Heyao Wang*, Weiliang Zhu*. Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening. Bioorg Med Chem Lett. 20(12) (2010):3675-3679
20. Hui Hu, Ling-Yan He, Zhen Gong, Ning Li, Yi-Na Lu, Qi-Wei Zhai, Hong Liu, Hua-Liang Jiang, Wei-Liang Zhu*, and He-Yao Wang*. A novel class of antagonists for the FFAs receptor GPR40. Biochemical and Biophysical Research Communications. 390(3) (2009):557-563
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