王飞虎 - 上海交通大学 - 生物医学工程学院

个人简介

王飞虎,博士，长聘教轨副教授，博士生导师，获国家优秀青年人才项目，上海市海外高层次人才。2016年博士毕业于上海交通大学和中国医药工业研究院，获医学博士学位。同年博士后获聘于约翰霍普金斯大学，先后师从Honggang Cui教授和Justin Hanes 教授。2021年通过绿色人才引进通道受聘于上海交通大学。主要研究方向包括智能药物递送系统、免疫治疗制剂和中药创新制剂的开发并用于肿瘤、自身免疫性疾病和神经损伤等重大疾病的精准治疗。已在Nat. Biomed. Eng., PNAS, Sci. Adv., ACS Nano, Adv. Drug Delive. Rev., JACS, Angew. Chem., Biomaterials, J. Control. Release 等国际权威学术期刊上发表研究论文45篇。对于有良好临床转化潜力的研究成果已申请6项PCT 或中国专利。主持国家自然科学基金、上海市科学技术委员会基金等项目。教育背景 2005.09-2009.07 理学学士, 西安交通大学 2009.09-2012.06 工学硕士, 山东大学 2012.09-2016.06 医学博士, 上海交通大学和中国医药工业研究院工作经历 2016.07-2021.05 博士后研究员，约翰霍普金斯大学 2021.06-至今长聘教轨副教授，博士生导师，上海交通大学科研项目 1. 国家自然科学基金委员会，青年科学基金项目， 2022.01-2024.12，在研，主持。 2. 上海市科学技术委员会，“科技创新行动计划”生物医药科技支撑专项，2022.04-2025.03，主持。

研究领域

新型药物递送系统多肽-药物偶联物和超分子药物免疫工程与免疫治疗中药创新制剂

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Feihu Wang*, Hao Su, Zeyu Wang, Caleb F. Anderson, Xuanrong Sun, Han Wang, Philippe Laffont, Justin Hanes*, Honggang Cui*. Supramolecular Filament Hydrogel as a Universal Immunomodulator Carrier for Immunotherapy Combinations. ACS Nano, 2023 https://doi.org/10.1021/acsnano.3c01748. 2. Feihu Wang, Qian Huang, Hao Su, Mingjiao Sun, Zeyu Wang, Ziqi Chen, Mengzhen Zheng, Rami W. Chakroun, Maya K. Monroe, Daiqing Chen, Zongyuan Wang, Noah Gorelick, Riccardo Serra, Han Wang, Yun Guan, Jung Soo Suk, Betty Tyler, Henry Brem, Justin Hanes, and Honggang Cui. Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma. Proceedings of the National Academy of Sciences，2023，e2204621120. 3. Qi Shang, Yabing Dong, Yun Su, Faith Leslie, Mingjiao Sun, Feihu Wang*, Local scaffold-assisted delivery of immunotherapeutic agents for improved cancer immunotherapy, Advanced Drug Delivery Reviews, 185 (2022), 114308. 4. Feihu Wang*, Hao Su, Dongqing Xu, Maya K Monroe, Caleb F Anderson, Weijie Zhang, Richard Oh, Zongyuan Wang, Xuanrong Sun, Han Wang, Fengyi Wan, Honggang Cui*, Therapeutic supramolecular tubustecan hydrogel combined with checkpoint inhibitor elicits immunity to combat cancer, Biomaterials, 279 (2021), 121182. 5. Feihu Wang＃, Hao Su＃, Dongqing Xu, Wenbing Dai, Weijie Zhang, Zongyuan Wang, Caleb Aderson, Mengzhen Zheng, Richard Oh, Fengyi Wan, Honggang Cui. Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel. Nature Biomedical Engineering. 4 (2020), 1090-1101. 6. Feihu Wang＃, Dongqing Xu＃, Hao Su, Weijie Zhang, Xuanrong Sun, Maya. K. Monroe, Rami W. Chakroun, Zongyuan Wang, Wenbing Dai, Richard Oh, Fengyi Wan, Honggang Cui. Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker-based immunotherapy. Science Advances. 6 (2020), eaaz8985. 7. Feihu Wang, Hao Su, Ran Lin, Rami Chakroun, Maya Monroe, Zongyuan Wang, Michael Porter, Honggang Cui. Supramolecular tubustecan hydrogel as chemotherapeutic carrier to improve tumor penetration and local treatment efficacy. ACS Nano. 14 (2020), 10083-10094. 8. Hao Su＃, Feihu Wang＃, Wei Ran, Weijie Zhang, Wenbing Dai, Han Wang, Caleb Anderson, Zongyuan Wang, Chao Zheng, Pengcheng Zhang, Yaping Li, Honggang Cui. The role of critical micellization concentration in efficacy and toxicity of supramolecular polymers. Proceedings of the National Academy of Sciences. 117 (2020), 4518-4526 (Co-first author).

学术兼职

担任ACS Nano, Adv. Funct. Mater., J. Immunother. Cancer, Nano Lett., J. Control. Release, Biomaterials等十余国际期刊审稿人。