个人简介
马斌,长聘教轨副教授,博士生导师。2005年获兰州大学生物科学专业学士学位。 2007年获得荷兰格罗宁根大学医学制药学专业优等硕士学位(cum laude)。2012年获荷兰特文特大学博士学位,并获得2011年度国家优秀自费留学生奖学金。2013年至2015年在瑞士苏黎世大学及附属儿童医院从事博士后研究工作。2015年10月加入上海交通大学生物医学工程学院。2016年获得上海高校青年东方学者称号。
教育背景
2007/10至2012/09, 荷兰特文特大学, 细胞与分子生物学, 博士
2005/09至2007/07, 荷兰格罗宁根大学, 医学制药学, 硕士
2001/09至2005/06, 兰州大学, 生物科学, 学士
工作经历
2015/10至现在, 上海交通大学, 生物医学工程学院, 副研究员
2014/02至2015/06, 瑞士苏黎世大学附属儿童医院, 博士后
2013/01至2014/08, 瑞士苏黎世大学, 博士后
教学工作
免疫疾病与肿瘤免疫基础 (32学时,研究生)
研究领域
致癌通路和肿瘤微环境,肿瘤内源性免疫逃逸机制,癌症的免疫疗法。
近期论文
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Yekehfallah V, Pahlavanneshan S, Sayadmanesh A, Momtahan Z, Ma B*, Basiri M*. Generation and functional characterization of PLAP CAR-T cells against cervical cancer cells. Biomolecules 2022; 12: 1296. *Corresponding author
Ji L, Peng P, Gui L, Yuan P, Qian W, Wang Y, Gao WQ*, Ma B*. CD24 is a superior immunotherapeutic target to PD-1 in a mouse model of Helicobacter-induced gastric cancer. Gastro Hep Advances 2022; 1(1):79-82. *Corresponding author
Yan J, Yuan P, Gui L, Wang Z, Yin P, Gao WQ, Ma B*. CCL28 downregulation attenuates pancreatic cancer progression through tumor cell-intrinsic and -extrinsic mechanisms. Technol Cancer Res Treat 2021; 20:15330338211068958. *Corresponding author
Wang C#, Yan J#, Yin P, Gui L, Ji L, Ma B*, Gao WQ*. β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer. OncoImmunology 2020; 9(1): e1809947. #Co-first author; *Corresponding author
Yin P, Gui L, Wang C, Yan J, Liu M, Ji L, Wang Y, Ma B*, Gao WQ*. Targeted delivery of CXCL9 and OX40L by mesenchymal stem cells elicits potent antitumor immunity. Mol Ther 2020; 28(12):2553-63. *Corresponding author
Ji L, Qian W, Gui L, Ji Z, Yin P, Lin GN, Wang Y, Ma B*, Gao WQ*. Blockade of β-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration. Cancer Res 2020; 80(10):2004-16. *Corresponding author
Ma B, Hottiger MO. Crosstalk between Wnt/β-catenin and NF-κB signaling during inflammation. Front Immunol 2016; 7:378.
Ma B, Fey M, Hottiger MO. WNT/β-catenin signaling inhibits CBP-mediated RelA acetylation and expression of a proinflammatory subset of NF-κB target genes. J Cell Sci 2015; 128:2430-2436.
Ma B, Zhong L, van Blitterswijk CA, Post JN, Karperien M. T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling. J Biol Chem 2013; 288:17552-8.
Ma B, van Blitterswijk CA, Karperien M. A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes. Arthritis Rheum 2012; 64:2589-600.
Ter Elst A*, Ma B*, Scherpen FJG, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES. Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia. Cancer Res 2011; 71:2761-71. *Co-first author