Kruss, Sebastian - Georg-August-Universitäten Göttingen

个人简介

2014- Liebig Research Group Leader, Institute for Physical Chemistry Goettingen 2012-2014 Postdoc, Massachusetts Institute of Technology (MIT) with Michael Strano 2008-2011 PhD in Physical Chemistry, Heidelberg University & Max Planck Institute for Intelligent Systems with Joachim Spatz 2002-2007 Diploma in Chemistry, Heidelberg University

研究领域

We explore and use the unique properties of nanomaterials to control and investigate processes in complex biological systems. The nanomaterials serve as building blocks to engineer functional nanoscaled devices that interface cells. These devices are able to collect information or control processes in cells and finally biological functions. A major biological motivation of our work is the understanding of complex chemical processes in cell circuits such as neural circuits in the brain. For this purpose, it is first of all necessary to know which molecules are released when and where. Then it is desirable to control cellular functions. Finally, all tools are merged together and interfaced with biological systems. While developing these new tools we study fundamental processes of nano materials in crowded biological solutions in order to gain a quantitative understanding of the underlying physical chemistry. Our long-term goal is to elucidate chemical communication in cell circuits and to engineer tools that can listen and talk with cells in their own (physical and chemical) language. Therefore we work on nanoscaled sensors, actuators and intelligent nanodevices.

近期论文

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M. Landry , L.Vukovic , S. Kruss , G. Bisker , A. Landry , S. Islam , R.M. Jain , K. Schulten , and M.S. Strano: Comparative Dynamics and Sequence Dependence of DNA and RNA Binding to Single Walled Carbon Nanotubes, Journal of Physical Chemistry C, (2015), accepted. DOI: 10.1021/jp511448e. G.L.C. Paulus, K.Y. Lee, N.F. Reuel, J. Zhang, Q.H.Wang, B.R. Grassbaugh, S. Kruss, B. Mu, C. Opel, D. Wittrup and M. S. Strano: A graphene-based physiometer array for the analysis of single biological cells. Scientific Reports, accepted. K. Amschler, L. Erpenbeck, S. Kruss, M. P. Schön: Nanoscale Integrin Ligand Patterns Determine Melanoma Cell Behavior, ACS Nano, (2014), DOI: 10.1021/nn502690b. M.P. Landry, S. Kruss, J. T. Nelson, G. Bisker, N.M. Iverson, N.F. Reuel and M.S. Strano: Experimental Tools to Study Molecular Recognition within the Nanoparticle Corona, Sensors, (2014), DOI: 10.3390/s140916196.. B. Mu, J. Zhang, T. P. McNicholas, N.F. Reuel, S. Kruss, M.S. Strano: Recent Advances in Molecular Recognition based on Nanoengineered Platforms, Accounts of Chemical Research, (2014), accepted. S. Kruss, M. Landry, E.V. Ende, B. Lima, N. F. Reuel, J. Zhang, J. Nelson, B. Mu, A. Hilmer, M. Strano: Neurotransmitter Detection Using Corona Phase Molecular Recognition on Fluorescent Single-Walled Carbon Nanotube Sensors, JACS, (2014), 136(2), 713-724, DOI: 10.1021/ja410433b. Q. H. Wang, D. O. Bellisario, L. W. Drahushuk, R. M. Jain, S. Kruss, M.P. Landry, S.G. Mahajan, S.F.E. Shimizu, Z. W. Ulissi, and M. S. Strano: Low Dimensional Carbon Materials for Applications in Mass and Energy Transport, Chemistry of Materials, (2014), 26(1), 172-183, DOI: 10.1021/cm402895e.