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Liu, Bo, Yu, Xueni, Liu, Liping, Wang, Lei, Wang, Jie, Huang, Qianqian, Xu, Zhongliang, Luo, Cheng, Lou, Liguang, Huang, Wei, Yang, Weibo. Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance. JOURNAL OF MEDICINAL CHEMISTRY. 2023, http://dx.doi.org/10.1021/acs.jmedchem.2c01424.
Hao Wang, Zhongyu Li, Xiangyang Chen, Jonathan J Wong, Tongyu Bi, Xiankun Tong, Zhongliang Xu, Mingyue Zhen, Yunhui Wan, Li Tang, Bo Liu, Xinlei Zong, Dandan Xu, Jianping Zuo, Li Yang, Wei Huang, Kendall N Houk, Weibo Yang. Multicomponent coupling and macrocyclization enabled by Rh(III)-catalyzed dual C–H activation: Macrocyclic oxime inhibitor of influenza H1N1. CHEM[J]. 2023, 9(3): 607-623, http://dx.doi.org/10.1016/j.chempr.2022.10.019.
Wenjing Ma, Zhuojia Xu, Yuhan Jiang, Jialin Liu, Dandan Xu, Wei Huang, Tiehai Li. Divergent Enzymatic Assembly of a Comprehensive 64‐Membered IgG N ‐Glycan Library for Functional Glycomics. ADVANCED SCIENCE. 2023, 10(30): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602528/.
Dongliang Guan, Jian Li, Feifei Chen, Jiaqi Li, Xiaolei Bian, Yue Yu, Xinxin Feng, Lefu Lan, Wei Huang. A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2023, 259: http://dx.doi.org/10.1016/j.ejmech.2023.115638.
Shi, Wei, Zhang, Jianxin, Liu, Liya, Li, Wanzhen, Liu, Zhi, Ren, Anni, Wang, Jie, Tang, Caihong, Yang, Yang, Xu, Dandan, Huang, Qianqian, Wang, Yongqin, Luo, Caili, Huang, Wei, Tang, Feng. Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates. JOURNAL OF MEDICINAL CHEMISTRY[J]. 2022,
Zou, Xiangman, Liu, Zhi, Liu, Liya, Shi, Wei, Li, Wanzhen, Guo, Zifen, Tang, Feng, Huang, Wei. Enhanced transglycosylation activity of an Endo-F3 mutant by ligand-directed localization. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2022, 20(15): 3086-3095, http://dx.doi.org/10.1039/d2ob00030j.
Long, Yiru, Sun, Jianhua, Song, TianZhang, Liu, Tingting, Tang, Feng, Zhang, Xinxin, Ding, Longfei, Miao, Yunqiu, Zhu, Weiliang, Pan, Xiaoyan, An, Qi, Qin, Mian, Tong, Xiankun, Peng, Xionghua, Yu, Pan, Zhu, Peng, Xu, Jianqing, Zhang, Xiaoyan, Zhang, Yachun, Liu, Datao, Chen, Ben, Chen, Huilin, Zhang, Leike, Xiao, Gengfu, Zuo, Jianping, Tang, Wei, Zhou, Ji, Li, Heng, Xu, Zhijian, Zheng, HongYi, Long, XinYan, Qin, Qiuping, Gan, Yong, Ren, Jin, Huang, Wei, Zheng, YongTang, Jin, Guangyi, Gong, Likun. CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity. CELL DISCOVERY[J]. 2022, 8(1): https://doaj.org/article/3c59c092141d418c8f84164569078712.
Zeng, Yue, Shi, Wei, Dong, Qian, Li, Wanzhen, Zhang, Jianxin, Ren, Xuelian, Tang, Caihong, Liu, Bo, Song, Yuanli, Wu, Yali, Diao, Xingxing, Zhou, Hu, Huang, He, Tang, Feng, Huang, Wei. A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 61(36): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000830729300001.
Lei, E, Tao, Huanyu, Jiao, Shang, Yang, Anming, Zhou, Yu, Wang, Min, Wen, Kang, Wang, Yi, Chen, Zhiyong, Chen, Xianhui, Song, Junfeng, Zhou, Cailing, Huang, Wei, Xu, Lili, Guan, Dongliang, Tan, Cuiyan, Liu, Haoran, Cai, Qingyun, Zhou, Kai, Modica, Justin, Huang, ShengYou, Huang, Wei, Feng, Xinxin. Potentiation of Vancomycin: Creating Cooperative Membrane Lysis through a "Derivatization-for-Sensitization" Approach. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2022, 144(23): 10622-10639, http://dx.doi.org/10.1021/jacs.2c03784.
Chen, Yao, Tang, Feng, Qin, Hongqiang, Yue, Xuyang, Nie, Yongzhan, Huang, Wei, Ye, Mingliang. Endo-M Mediated Chemoenzymatic Approach Enables Reversible Glycopeptide Labeling for O-GlcNAcylation Analysis. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, http://dx.doi.org/10.1002/anie.202117849.
Zeng, Yue, Tang, Feng, Shi, Wei, Dong, Qian, Huang, Wei. Recent advances in synthetic glycoengineering for biological applications. CURRENT OPINION IN BIOTECHNOLOGYnull. 2022, 74: 247-255, http://dx.doi.org/10.1016/j.copbio.2021.12.008.
Shi, Wei, Li, Wanzhen, Zhang, Jianxin, Li, Tiehai, Song, Yakai, Zeng, Yue, Dong, Qian, Lin, Zeng, Gong, Likun, Fan, Shuquan, Tang, Feng, Huang, Wei. One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates. ACTA PHARMACEUTICA SINICA B[J]. 2022, 12(5): 2417-2428, http://dx.doi.org/10.1016/j.apsb.2021.12.0132211-3835.
Li, Jian, Zhu, Yue, Liu, Bo, Tang, Feng, Zheng, Xing, Huang, Wei. An Atom-Economic Inverse Solid-Phase Peptide Synthesis Using Bn or BcM Esters of Amino Acids. ORGANIC LETTERS[J]. 2021, 23(19): 7571-7574, http://dx.doi.org/10.1021/acs.orglett.1c02769.
Shi, Weiwei, Chen, Feifei, Zou, Xiangman, Jiao, Shang, Wang, Siqi, Hu, Yu, Lan, Lefu, Tang, Feng, Huang, Wei. Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2021, 45: http://dx.doi.org/10.1016/j.bmcl.2021.128122.
Song, Yakai, Deng, Xiaojie, Shi, Wei, Tang, Feng, Huang, Wei, Gong, Likun, Qin, Qiuping. A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies. JOURNAL OF IMMUNOLOGICAL METHODS[J]. 2021, 499: http://dx.doi.org/10.1016/j.jim.2021.113180.
Pan, Deng, Tang, Yubo, Tong, Jiao, Xie, Chengmei, Chen, Jiaxi, Feng, Chunchao, Hwu, Patrick, Huang, Wei, Zhou, Dapeng. An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer. CANCER MEDICINE[J]. 2020, 9(24): 9529-9540, https://www.doi.org/10.1002/cam4.3554.
Lu, Dan, Yin, Hongli, Wang, Siyao, Tang, Feng, Huang, Wei, Wang, Ping. Chemical Synthesis of the Homogeneous Granulocyte-Macrophage Colony-Stimulating Factor Through Se-Auxiliary-Mediated Ligation. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(3): 1652-1660, https://www.webofscience.com/wos/woscc/full-record/WOS:000513080700034.
Ming Li, Yaqiang Bai, Jiaorui Zhou, Wei Huang, Jingyu Yan, Jia Tao, Qingjie Fan, Yang Liu, Di Mei, Qiulong Yan, Jieli Yuan, Patrice Malard, Zhongfu Wang, Jianguo Gu, Naoyuki Tanigchi, Wenzhe Li. Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the l-Fucose Metabolism of Gut Bifidobacterium spp. and Lactobacillus spp.. MBIO[J]. 2019, 10(2): IR_Article.
Zhao, Kai, Tang, Feng, Shi, Wei, Hong, Haofei, Zhou, Zhifang, Huang, Wei, Wu, Zhimeng. One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling. BIOORGANIC CHEMISTRY[J]. 2019, 91: 103114-, http://dx.doi.org/10.1016/j.bioorg.2019.103114.
李名洁, 唐峰, 郭伟来, 徐莉英, 黄蔚. 蛋黄及其提取物中唾液酸糖肽的分离与测定. 沈阳药科大学学报[J]. 2018, 35(9): 769-, http://lib.cqvip.com/Qikan/Article/Detail?id=676331666.
Zhou, Dapeng, Xu, Lan, Huang, Wei, Tonn, Torsten. Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy. MOLECULES[J]. 2018, 23(6): https://doaj.org/article/78cd2501b0134d6b8c4929a25d7f79e7.
Zhou, Bin, Faridoon, Tian, Xiaobo, Li, Jian, Guan, Dongliang, Zheng, Xing, Guo, Yu, Huang, Wei. On-resin peptide ligation via C-terminus benzyl ester. CHINESE CHEMICAL LETTERS[J]. 2018, 29(7): 1123-1126, http://dx.doi.org/10.1016/j.cclet.2018.03.021.
Yang, Liyun, Liu, Xiaofang, Yang, Yang, Yang, Linlin, Liu, Kaiwen, Tang, Yubo, Zhang, Min, Tan, Minjia, Cheng, Shanmei, Xu, Yechun, Yang, Huaiyu, Liu, Zhijie, Song, Gaojie, Huang, Wei. Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities. ACTA PHARMACOLOGICA SINICA[J]. 2017, 38(1): 56-68,
Huang Yu. Asp side-chain benzyl ester as a multi-functionalization precursor for synthesis of branched and cyclic RGD peptides. Synlett. 2017,
Li, Xiaona, Zhou, Mang, Huang, Wei, Yang, Huaiyu. N-glycosylation of the beta(2) adrenergic receptor regulates receptor function by modulating dimerization. FEBS JOURNAL[J]. 2017, 284(13): 2004-2018, http://dx.doi.org/10.1111/febs.14098.
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