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个人简介

教育经历:   2003.8 - 2010.10 美国南加州大学,生物信息,博士   1999.9 - 2003.7 复旦大学,生物科学,学士   工作经历:   2015.05 - 至今 上海药物研究所,研究员,研究组长   2014.04 - 2015.05 Illumina Inc. 圣地亚哥,生物信息科学家   2010.11 - 2014.04 加利福尼亚大学洛杉矶分校,博士后

研究领域

1.药物基因数据库。 2.生物信息方法:药物biomarker发现、疾病risk预测、细分优化人群、大数据-based治疗方案推荐方法。 3.个性化药物开发: Biomarker/靶标发现、组学层面细分和优化药物目标病人群体、研究耐药机制。

近期论文

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1.YS Huang, V Ramensky, et al., Nelson Freimer (2015) Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits. BMC Biology (http://www.biomedcentral.com/1741-7007/13/41/abstract ) 2.MW Horton, AM Hancock*, YS Huang*, C Toomajian*, S Atwell, A Auton, NW Muliyati, A Platt, FG Sperone, BJ Vilhjálmsson, M Nordborg, JO Borevitz, J Bergelson (2012): Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nature Genetics 116 citations. 3.YS Huang#, M Horton, BJ Vilhjálmsson, Ü Seren, D Meng, C Meyer, MA Amer, JO Borevitz, J Bergelson, M Nordborg (2011): Analysis and visualization of Arabidopsis thaliana GWAS using web 2.0 technologies. http://arabidopsis.usc.edu/ Database 2011; (#: corresponding author) 9 citations. 4.S Atwell*, YS Huang*, BJ Vilhjálmsson*, G Willems*, M Horton, Y Li, D Meng, A Platt, A Tarone, TT. Hu, R Jiang, NW Muliyati, X Zhang, MAi Amer, I Baxter, B Brachi, J Chory, C Dean, M Debieu, J de Meaux, JR Ecker, N Faure, JM Kniskern, JD Jones, T Michael, A Nemri, F Roux, DE Salt, C Tang, M Todesco, MB Traw, D Weigel, P Marjoram, JO Borevitz, J Bergelson, M Nordborg (2010): Genome-wide association study of 107 phenotypes in a common set of Arabidopsis thaliana inbred lines. Nature (*: equal contribution.) 577 citations. 5.A Platt, M Horton*, YS Huang*, Y Li*, A Anastasio, NW Mulyati, J Ågren, O Bossdorf, D Byers, K Donohue, M Dunning, E Holub, A Hudson, V Le Corre, O Loudet, F Roux, N Warthmann, D Weigel, L Rivero, R Scholl, M Nordborg, J Bergelson, JO. Borevitz (2010): The Scale of Population Structure in Arabidopsis thaliana. Plos Genetics (*: equal contribution.) 144 citations. 6.Y Huang*, H Li*, H Hu, X Yan, MS. Waterman, H Huang and XJ Zhou (2007): Systematic discovery of functional modules and context-specific functional annotation of human genome. Bioinformatics (ISMB 2007) 23:i222-229. (*: equal contribution.) 62 citations.

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