当前位置: X-MOL首页全球导师 国内导师 › 杨伟波

个人简介

教育经历 2015年12月–2016年9月 美国Scripps研究所,研究助理,导师:Peter G. Schultz 2013年12月–2015年12月 美国Scripps研究所,研究助理,导师:Jin-Quan Yu 2013年9月–2013年10月 德国海德堡大学,研究助理,导师:Stephen Hashmi 2010年9月–2013年8月 德国海德堡大学,博士,导师:Stephen Hashmi 2007年9月–2010年7月 大连理工大学,硕士, 导师:刘春 2003年9月–2007年7月 辽宁科技大学,学士, 导师:张志强 工作经历 2016.10-至今,中科院上海药物所担任研究员、课题组长

研究领域

类天然产物以及功能型大环库(大环内脂,环肽)的构建 过渡金属催化卡宾偶联、碳氢活化、自由基等新型反应设计 蛋白-蛋白相互作用(PPI)小分子抑制剂设计与合成 针对耐药性开展双靶点小分子抑制剂研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Bichao Song, Peipei Xie, Yingzi Li, Jiping Hao, Lu Wang, Xiangyang Chen, Zhongliang Xu, Haitian, Quan, Liguang, Lou, Yuanzhi Xia,* K. N. Houk,* and Weibo Yang*, Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Bioactive Macrocyclic Inhibitors.J. Am. Chem. Soc. 2020, 142, 9982-9992 Lu Chen, Haitian Quan, Zhongliang Xu, Hao Wang, Yuanzhi Xia, Liguang Lou,* Weibo Yang,* A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation.Nat. Commun. 2020, 11, 2151. Yi Xu, Lu Chen, Yu-wen Yang, Zhiqiang Zhang, Weibo Yang*, Vinylethylene Carbonates as α,β-Unsaturated Aldehyde Surrogates for Regioselective [3 + 3] Cycloaddition.Org. Lett., 2019, 21, 6674-6678 Jiping Hao, Yi Xu, Zhongliang Xu, Zhiqiang Zhang, Weibo Yang*, Pd-Catalyzed Three-Component Domino Reaction of Vinyl Benzoxazinanones for Regioselective and Stereoselective Synthesis of Allylic Sulfone-Containing Amino Acid Derivatives. Org. Lett., 2018, 20, 7888-7892 Yuwen Yang, Weibo Yang*, Divergent synthesis of N-heterocycles by Pd-catalyzed controllable cyclization of vinylethylene carbonates.Chem. Commun., 2018, 24, 12182-12185 Lei Deng, Arjan W. Kleij,* Weibo Yang*, Diversity‐Orientated Stereoselective Synthesis through Pd‐Catalyzed Switchable Decarboxylative C-N/C-S Bond Formation in Allylic Surrogates. Chem. Eur. J., 2018, 24, 19156-19161 Weibo Yang, Shengqing Ye, YvonneSchmidt, Dean Stamos,* Jin-QuanYu*: Ligand-Promoted C(sp3)-H Olefination en Route to Multi-functionalized Pyrazoles.Chem. Eur. J. 2016, 22, 7059-7062. Shengqing Ye, Weibo Yang, Timothy Coon, Dewey Fanning, Tim Neubert, Dean Stamos, Jin-Quan Yu*: Heterocyclic Carbene Ligand-Enabled C(sp3 )-H Arylation of Piperidine and Tetrahydropyran Derivatives.Chem. Eur. J. 2016, 22, 4748-4752. Weibo Yang, Shengqing Ye, Dewey Fanning, Timothy Coon, Yvonne Schmidt, Paul Krenitsky, Dean Stamos* and Jin-Quan Yu*: Orchestrated Triple C–H Activation Reactions Using Two Directing Groups: Rapid Assembly of Complex Pyrazoles. Angew. Chem. Int. Ed. 2015, 54, 2501-2504. Weibo Yang, A. Stephen K. Hashmi*: Mechanistic insights of the gold chemistry of allenes. Chem. Soc. Rev. 2014, 43, 2941–2955 Yang Yu+, Weibo Yang+, Daniel Pfl?sterer, A. Stephen K. Hashmi*: Dehydrogenative Meyer-Schuster-like Rearrangement: A Gold-Catalyzed Reaction Generating an Alkyne. Angew. Chem. Int. Ed. 2014, 53, 1144-1147. (Y. Yu and W. Yang contributed equally to this work) Yang Yu+, Weibo Yang+, Frank Rominger, A. Stephen K. Hashmi*: In Situ Generation of Nucleophilic Allenes by the Gold-Catalyzed Rearrangement of Propargylic Esters for the Highly Diastereoselective Formation of Intermolecular C(sp3)-C(sp2) Bonds.Angew. Chem. Int. Ed. 2013, 52, 7586-7589. (Y. Yu and W. Yang contributed equally to this work) A. Stephen K. Hashmi*, Weibo Yang, Yang Yu, M. Hansmann, Matthias Rudolph, Frank Rominger: Gold-Catalyzed Formal 1,6-Acyloxy Migration Leading to 3,4-Disubstituted Pyrrolidin-2-ones. Angew. Chem. Int. Ed. 2013, 52, 1329-1332. (Highlighted in Synfacts) A. Stephen K. Hashmi*, Weibo Yang, Frank Rominger: Gold(I)-Catalyzed Formation of Benzo[b]furans from 3-Silyloxy-1,5-enynes. Angew. Chem. Int. Ed. 2011, 50, 5762-5765. Weibo Yang, Long Huang, Yang Yu, Daniel Pfl?sterer, Frank Rominger, A. Stephen K. Hashmi*:Highly Diasteroselective and Regioselective Copper-Catalyzed Acylnitroso Dearomatization Reaction under Aerobic Oxidation Conditions. Chem. Eur. J. 2014, 20, 3927-3931 Weibo Yang, Tao Wang, Yang Yu, Shuai Shi, Tuo Zhang, A. Stephen K. Hashmi*: Nitrones as Trapping Reagents of α,β-Unsaturated Carbene Intermediates – [1,2]Oxazino[5,4-b]indoles by a Platinum-Catalyzed Intermolecular [3+3] Cycloaddition. Adv. Synth. Catal. 2013, 355, 1523-1528. (Highlighted in Synfacts) Weibo Yang, Yang Yu, Tuo Zhang, Max M. Hansmann, Daniel Pfl?sterer, A. Stephen K. Hashmi*: Gold-Catalyzed Highly Diastereoselective Synthesis of Functionalized 3,4-Disubstituted Butyrolactams via Phosphatyloxy or Carbonate Double Migrations. Adv. Synth. Catal. 2013, 355, 2037-2043. (Highlighted in Synfacts) A. Stephen K. Hashmi*, Weibo Yang, Frank Rominger: Gold-Catalysis: Highly Efficient and Regio-Selective Carbonyl Migration in Alkynyl-Substituted Indole-3-Carboxamides Leading to Azepino[3,4-b]indol-1-ones. Adv, Synth, Catal. 2012, 354, 1273-1279. (Highlighted in Synfacts) A. Stephen K. Hashmi*, Weibo Yang, Frank Rominger: Gold-Catalysis: Gold(I)-Catalyzed Rearrangement of 3-Silyloxy-1,5-enynes: An Efficient Synthesis of Benzo[b]thiophenes, Dibenzothiophenes, Dibenzofurans, and Indole Derivatives. Chem. Eur. J. 2012, 18, 6576-6580. Weibo Yang, Liu Chun*, Jieshan Qiu: In Situ Formation of N,O-Bidentate Ligand via the Hydrogen Bond for Highly Efficient Suzuki Reaction of Aryl Chlorides. Chem. Commun. 2010, 2659-2661. (Highlighted in Synfacts) Liu Chun*, Weibo Yang: A fast and oxygen-promoted protocol for the ligand-free Suzuki reaction of 2-halogenated pyridines in aqueous media.Chem. Commun. 2009, 6267-6269. A. Stephen K. Hashmi*, Tobias H?ffner, Weibo Yang, Sreekumar Pankajakshan, Sascha Sch?fer, Lara Schultes, Frank Rominger, Wolfgang Frey: Gold Catalysis: Non-Spirocyclic Intermediates in the Conversion of Furanynes by the Formal Insertion of an Alkyne into an Aryl–Alkyl C–C Single Bond. Chem. Eur. J. 2012, 18, 10480-10486. Shuai Shi, Tao Wang, Weibo Yang, Matthias Rudolph, A. Stephen K. Hashmi*: Gold Catalyzed Synthesis of Glyoxals via Oxidation of Terminal Alkynes; One-Pot Synthesis of Quinoxalines. Chem. Eur. J. 2013, 19, 6576-6580.

推荐链接
down
wechat
bug