个人简介
EDUCATION
Ph. D. in Physics, West Virginia University, USA, 2004
Ph. D. in Optics, Institute of Physics, Chin. Acad. Sci. 1999
B. S. in Physics, Jilin University, 1995
CAREER
2015-present, Professor, College of Chemistry, Beijing Normal Univ.
2007-2015, Associate Professor, College of Chemistry, Beijing Normal Univ.
2006-2007, Research Scientist, Institute of Physics, Chin. Acad. Sci.
2004-2006, Postdoc., Max-Plank Institute of Colloids and Interfaces, Germany
AWARDS
Excellent Graduate Course of Beijing Normal University, 2014
Talent of Beijing Normal University, 2012
讲授课程
物理化学，数学物理方法，化学测量与计算实验
科研项目
膜弯曲的产生机制及其对蛋白质吸附的影响，国家自然科学基金面上项目，2017年-2020年，65万
多层次自组装的多尺度模拟，国家自然科学基金面上项目，2014年-2017年，80万
脂筏介导的跨膜信号传递的理论模拟，国家自然科学基金重大研究计划培育项目，2012年-2015年，65万
抗菌肽和生物膜相互作用的耗散粒子动力学研究，国家自然科学基金面上项目，2009年-2011年，30万
近期论文
查看导师最新文章
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Polymyxins Induce Lipid Scrambling and Disrupt the Homeostasis of Gram-Negative Bacteria Membrane, Lei Fu, Xiangyuan Li, Shan Zhang, Yi Dong, Weihai Fang, and Lianghui Gao*, Biophys. J. 121,18 (2022).
Structure and Formation Mechanism of Antimicrobial Peptides Temporin B- and L-Induced Tubular Membrane Protrusion, Shan Zhang, Ming Ma, Zhuang Shao, Jincheng Zhang, Lei Fu, Xiangyuan Li, Weihai Fang, and Lianghui Gao*, Int. J. Mol. Sci. 22,20 (2021).
Development of Accurate Coarse-Grained Force Fields for Weakly Polar Groups by an Indirect Parameterization Strategy, Junjie Song, Mingwei Wan, Ying Yang, Lianghui Gao*, and Weihai Fang, Phys. Chem. Chem. Phys. 23,36 (2021).
Development of Coarse-grained Force Field for Alcohols: an Efficient Meta-Multilinear Interpolation Parameterization Algorithm, Mingwei Wan, Junjie Song, Ying Yang, Lianghui Gao*, and Weihai Fang, Phys. Chem. Chem. Phys. 23,9 (2021).
Polymyxin B Loosens Lipopolysaccharide Bilayer but Stiffens Phospholipid Bilayer, Lei Fu, Mingwei Wan, Shan Zhang, Lianghui Gao*, and Weihai Fang, Biophys. J. 118,1 (2020).
Development of Coarse-Grained Force Field by Combining Multilinear Interpolation Technique and Simplex Algorithm, Mingwei Wan, Junjie Song, Wenli Li, Lianghui Gao*, and Weihai Fang, J. Comput. Chem. 41,8 (2019).
Peripheral Antimicrobial Peptide Gomesin Induces Membrane Protrusion, Folding, and Laceration, Shan Zhang, Lei Fu, Mingwei Wan, Junjie Song Lianghui Gao*, and Weihai Fang, Langmuir 335,40 (2019).
Peptide—Lipid Interaction Sites Affect Vesicles’ Responses to Antimicrobial Peptides, Yu Shi, Mingwei Wan, Lei Fu, Shan Zhang, Shiyuan Wang, Lianghui Gao*, and Weihai Fang, Biophys. J. 115,1 (2018).
Implicit-solvent dissipative particle dynamics force field based on a four-to-one coarse-grained mapping scheme, Mingwei Wan, Lianghui Gao*, and Weihai Fang, PLOS ONE 5, 0198049 ( 2018).
Theories and Applications of Mixed Quantum-Classical Non-adiabatic Dynamics, Lianghui Gao*, Bin-bin Xie, Weihai Fang, Chin. J. Chem. Phys. 31,12 (2018).
Formation Mechanism and Properties of Polyelectrolyte Multilayer-Supported Lipid Bilayers: A Coarse-Grained Molecular Dynamics Study, Caixia Wen, Mingwei Wan, Xiaoxu Li, Qiang He, Lianghui Gao*, and Weihai Fang, ACS Omega 2, 910 ( 2017).
Self-assembly of gold nanorods coated with phospholipids: a coarse-grained molecular dynamics study，Mingwei Wan, Xiaoxu Li, Lianghui Gao*, and Weihai Fang，Nanotechnology 27, 465704 (2016).
Dissipative Particle Dynamics Simulations for Phospholipid Membranes Based on a Four-To-One Coarse-Grained Mapping Scheme, Xiaoxu Li, Lianghui Gao*, and Weihai Fang, PLOS ONE 11, 0154568 (2016).
Mechanism of Inhibition of Human Islet Amyloid Polypeptide-Induced Membrane Damage by a Small Organic Fluorogen，Xiaoxu Li, Minwei Wan, Lianghui Gao*, and Weihai Fang, Sci. Rep. 6, 21614 (2016).
Nanodomain Formation of Ganglioside GM1 in Lipid Membrane: Effects of Cholera Toxin-Mediated Cross-Linking, Huijiao Sun, Licui Chen, Lianghui Gao*, and Weihai Fang, Langmuir 31, 9105 (2015).
Theoretical Insight into the Relationship between the Structures of Antimicrobial Peptides and Their Actions on Bacterial Membranes, Licui Chen, Xiaoxu Li, Lianghui Gao*, and Weihai Fang, J. Phys. Chem. B 119, 850 (2015).
Effects of Antimicrobial Peptide Revealed by Simulations: Translocation versus Membrane Corrugation, Licui Chen, Nana Jia, Lianghui Gao*, Weihai Fang, and L. Golubovic, Int. J. Mol. Sci. 14, 7932 (2013).
The folding dynamics and infrared spectra of a photocleabaged tetrapeptide predicted by theoretical simulations, Tiantian Jiao, Lianghui Gao*, Xuebo Chen, and Weihai Fang, J. Phys. Chem. B 116, 14318 (2012).
How the antimicrobial peptides kill bacteria: computational physics insights, Licui Chen, Lianghui Gao*, Weihai Fang, and L. Golubovic, Commun. Comput. Phys. 11, 709 (2012).
Semi-bottom-up coarse graining of water based on microscopic simulations, Lianghui Gao* and W. Fang, J. Chem. Phys. 135, 184101 (2011).
Self-Assembly of Lamellar Lipid-DNA Complexes Simulated by Explicit Solvent Counterion Model，Lianghui Gao*, Jun Cao, and Weihai Fang, J. Phys. Chem. B 114, 7261 (2010).
Theoretical Insight into the Photodegradation of a Disulfide Bridged Cyclic Tetrapeptide in Solution and Subsequent Fast Unfolding-Refolding Events, Xuebo Chen, Lianghui Gao*, Weihai Fang, et al, J. Phys. Chem. B 114, 15 (2010).
Communications: Self-energy and corresponding virial contribution of electrostatic interactions in dissipative particle dynamics: Simulations of cationic lipid bilayers, Lianghui Gao* and W. Fang, J. Chem. Phys. 132, 031102 (2010).
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