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个人简介

陈美,副教授,硕士研究生导师。2016年8月博士毕业于厦门大学无机化学专业,导师为郑南峰教授。目前主要从事多功能纳米生物材料的制备及其在生物传感和疾病诊疗中的应用研究。主持国家自然科学基金青年项目和面上项目各一项,湖南省自然科学基金面上项目和长沙市自然科学基金。 2020/01-至今,  湖南大学,材料科学与工程学院,副教授 2016/10-2019/12,湖南大学,材料科学与工程学院,助理教授 教育背景 2014/09-2015/11,美国亚利桑那州立大学,生物设计研究院,导师:Yung Chang教授,国家公派联合培养博士生 2010/09-2016/09,厦门大学,化学化工学院,导师:郑南峰教授,博士 2006/09-2010/06,中国地质大学(武汉),材料科学与化学工程学院,学士

研究领域

研究方向:新型纳米材料的可控合成与制备;纳米肿瘤诊疗试剂的设计合成与应用

近期论文

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学术成果 [19] X. Li, H. Hu, Y. Shi, Y. Liu, M. Zhou, Z. Huang, J. Li, G. Ke, M. Chen*, X. Zhang, PtSnBi nanoplates enable photoacoustic imaging-guided highly efficient photothermal tumor ablation, Chemistry - A European Journal, 2023 [18] M. Zhou, Y. Yin, Y. Shi, Z. Huang, Y. Shi, M. Chen*, G. Ke, X. Zhang, Spherical Nucleic Acid Reporters-based Cascade CRISPR/Cas12a Amplifier for Stable and Sensitive Biosensing of Circulating Tumor DNA, Chemical Communications, 2022(58), 4508-4511. [17] Y. Liu, X. Li, Y. Shi, Y. Wang, X. Zhao, X. Gong, R. Cai, G. Song, M. Chen*, X. Zhang, Two-dimensional intermetallic PtBi/Pt core/shell nanoplates overcome tumor hypoxia for enhanced cancer therapy, Nanoscale, (13)2021, 14245-14253. [16] Y. Liu, J. Li, M. Chen*, X. Chen, N. Zheng*, Palladium-based nanomaterials for cancer imaging and therapy, Theranostics, (10)2020, 10057. [15] Z. Guo#, L. Yang#, M. Chen#, X. Wen, H. Liu, J. Li, D. Xu, Y. An, C. Shi, J. Li, Molecular imaging of advanced atherosclerotic plaques with folate receptor-targeted 2D nanoprobes, Nano Res., (13)2020, 173-182. [14] Y. Yang, M. Chen*, Y. Wu, P. Wang, Y. Zhao, W. Zhu, Z. Song, X.-B. Zhang*, Ultrasound assisted one-step synthesis of Au@ Pt dendritic nanoparticles with enhanced NIR absorption for photothermal cancer therapy, RSC Adv., (9)2019, 28541-28547. [13] D. Liu, Y. Lv, M. Chen*, D. Cheng*, Z. Song, L. Yuan, X. Zhang, A long wavelength emission two-photon fluorescent probe for highly selective detection of cysteine in living cells and an inflamed mouse model, J. Mater. Chem. B, (7)2019, 3970-3975. [12] J. Wang, D. Cheng, L. Zhu, P. Wang, H.-W. Liu, M. Chen, L. Yuan, X.-B. Zhang, Engineering dithiobenzoic acid lactone-decorated Si-rhodamine as a highly selective near-infrared HOCl fluorescent probe for imaging drug-induced acute nephrotoxicity, Chem. Commun., (55)2019, 10916-10919. [11] X. Hu, G. Ke*, L. Liu, X. Fu, G. Kong, M. Xiong, M. Chen*, X.-B. Zhang*, Valency-controlled molecular spherical nucleic acids with tunable biosensing performances, Anal. Chem., (91)2019, 11374-11379. [10]  Y. Yang#, M. Chen#, B. Wang, P. Wang, Y. Liu, Y. Zhao, K. Li, G. Song, X.B. Zhang*, W. Tan, NIR‐II driven plasmon‐enhanced catalysis for a timely supply of oxygen to overcome hypoxia‐induced radiotherapy tolerance, Angew. Chem. Int. Ed., (58)2019, 15069-15075. [9] W. Zhu, M. Chen*, Y. Liu, Y. Tian, Z. Song, G. Song*, X. Zhang, A dual factor activated metal–organic framework hybrid nanoplatform for photoacoustic imaging and synergetic photo-chemotherapy, Nanoscale, (11)2019, 20630-20637. [8] Y. Wang, M. Chen*, S. Wang, S. Du, X. Zheng, X. Jiang, S. Huan*, X. Zhang, Size‐tunable two‐dimensional Pd@ Au nanoplates as a platform for fluorescence sensing, Journal of the Chinese Chemical Society, (65)2018, 1251-1258. [7] Z. D. Guo#, M. Chen#, C. Y. Peng, C. R. Shi, G. F. Fu, X. J. Wen, R. Q. Zhuang, X. H, Su, T. Liu, N. F.  Zheng*, X. Z. Zhang*, pH-sensitive radiolabeled and superfluorinated ultra-small palladium nanosheet as a high-performance multimodal platform for tumor theranostics, Biomaterials, (179) 2018, 134-143.    [6] M. Chen#, Z. D. Guo#. Q. H. Chen, J. P. Wei, J. C. Li, C. R. Shi, D. Xu, D. W. Zhou, X. Z. Zhang*, N. F. Zheng*,  Pd nanosheets with their surface coordinated by radioactive iodide as a high-performance theranostic nanoagent for orthotopic hepatocellular carcinoma imaging and cancer therapy, Chem. Sci.,  (9) 2018, 4268-4274. [5] M. Chen#, S. Z. Chen#, C. Y. He#, S. G. Mo, X. Y. Wang, G. Liu*, N. F. Zheng*, Safety profile of two dimensional Pd nanosheets for photothermal therapy and photoacoustic imaging, Nano Res., 10 (2017), 1234-1248. [4] M. Chen, S. H. Tang, Z. D. Guo, X. Y. Wang, S. G. Mo, X. Q. Huang, G. Liu*, N. F. Zheng*, Core-shell Pd@Au nanoplates as theranostic agents for in-vivo photoacoustic imaging, CT imaging, and photothermal therapy, Adv. Mater., 26 (2014), 8210-8216. [3] K.M. Au#, M. Chen#, S.P. Armes*, N. F. Zheng*, Near-infrared light-triggered irreversible aggregation of poly (oligo (ethylene glycol) methacrylate)-stabilised polypyrrole nanoparticles under biologically relevant conditions, Chem Commun., 49 (2013) 10525-10527. [2] M. Chen, B. H. Wu, J. Yang, N. F. Zheng*, Small adsorbate-assisted shape control of Pd and Pt nanocrystals, Adv. Mater., 24 (2012) 862-879. [1] M. Chen, X. L. Fang, S. H. Tang, N. F. Zheng*, Polypyrrole nanoparticles for high-performance in vivo near-infrared photothermal cancer therapy, Chem Commun., 48 (2012) 8934-8936.

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