王俊亚 - 上海海洋大学 - 水产与生命学院

个人简介

王俊亚，男，1986年7月生，籍贯河南商丘，中共党员，博士，水产养殖系讲师/专任教师；2018年10月-2020年12月于上海海洋大学水产养殖学博士后流动站进行博士后研究。2021年入职水产与生命学院。主要承担本科生《微生物学》课程教学工作，讲授本科生《免疫学》，研究生《酶与蛋白质》、《全英分子免疫学》和《水产动物医学前沿》等课程教学工作。近5年在Journal of Immunology, Fish shellfish Immunology, Developmental and Comparative Immunology, Frontiers in Immunology等期刊发表论文30余篇，其中以第一作者或通讯作者发表论文10篇。教育背景 2013.09–2018.06，中国农业大学，农学博士学位 2010.09–2013.06，河南农业大学，农学硕士学位 2006.09–2010.06，河南农业大学，工学学士学位主持和参与的科教项目 [1] 上海海洋大学青年教师科研启动基金，草鱼IL-4/13A和IL-4/13B结构与功能的比较分析研究，2022/01-2022/12，主持。 [2] 上海海洋大学水产与生命学院水产高峰学科开放课题，一种新型鱼类细胞因子的结构与免疫功能研究，2021-2022，主持。 [3] 南海水产经济动物增养殖重点实验室开放课题、KFKT2019YB06、草鱼白细胞介素-2及其受体结构与功能的研究、2019/04-2021/04、已结题，主持。 [4] 自然科学基金重点项目，32030112，草鱼CD4 T辅助（Th）细胞免疫系统及其应答病毒感染的分子机理研究，2021/01-2025/12，285万，参与，排名第三。 [5] 上海市“科技创新行动计划”“一带一路”国际合作项目，1939074310，鱼类抗菌肽的挖掘与潜在产业应用，2019/11-2021/10，30万元，参与，排名第三。 [6] 科技部，重点研发计划“蓝色粮仓科技创新”重点专项“重要水产养殖生物抗病和抗逆性状的遗传基础与调控机制”-子课题，2018YFD0900302-4，虹鳟抗传染性膜坏死病毒感染的分子基础，2018/12-2022/12，74万元，参与，排名第二。申请和授权专利情况 [1] 王俊亚，肖贺贺，邹钧，运胜冉，分泌抗草鱼IL-4/13B单克隆抗体的杂交瘤细胞株及单克隆抗体和应用。发明专利号申请号：202211039180.5。 [2] 王俊亚，陈静，邹钧，桂朗，刘琴，分泌抗鲤科疱疹病毒3型IL-10单克隆抗体的杂交瘤细胞株、单克隆抗体和应用。发明专利号申请号：202211038900.6。

研究领域

1. 鱼类免疫分子和病原致病因子结构与功能的研究； 2. 鱼类免疫防御的分子机理研究； 3. 渔用疫苗研制与应用；

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1] Zhao Jia, Jianhua Feng, Gaoliang Yuan, Hehe Xiao, Huifeng Dang,Yanwei Zhang, Kangyong Chen, Jun Zou, Junya Wang*. The Meteorin-like cytokine is upregulated in grass carp after infection with Aeromonas hydrophila Dev Comp Immunol 141 (2023), 104632. [2] Yanjie Shi, Kangyong Chen, Xin Zhao, Yanan Lu, Wenji Huang, Jiahong Guo, Ning Ji, Zhao Jia, Hehe Xiao, Huifeng Dang, Jun Zou*, Junya Wang*. IL-27 suppresses spring viremia of carp virus replication in zebrafish. Fish shellfish Immunol 133 (2023), 108530. [3] Huifeng Dang, Zeinab Hassan, Zhao Jia, Yaxin Wu, Hehe Xiao, Wenji Huang, Xu Guo, Xin Zhao, Yaoguo Li, Jun Zou, Junya Wang* Grass carp IL-20 binds to IL-20R2 but induces STAT3 phosphorylation via IL-20R1. Fish shellfish Immunol 132 (2023), 108445. [4] Xiaozhen Zhu#, Junya Wang#, Zhao Jia, Jianhua Feng, Bangjie Wang, Zixuan Wang, Qin Liu, Kaizheng Wu, Wenji Huang, Xin Zhao, Huifeng Dang, and Jun Zou*. Novel Dimeric Architecture of an IFN-gamma-Related Cytokine Provides Insights into Subfunctionalization of Type II IFNs in Teleost Fish, J Immunol. 209 (2022):2203-2214. [5] Zixuan Wang, Jiawen Xu, Jianhua Feng, Kaizheng Wu, Kangyong Chen, Zhao Jia, Xiaozhen Zhu, Wenji Huang, Xin Zhao, Qin Liu, Bangjie Wang, Xinhua Chen, Junya Wang*, Jun Zou*. Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish. Front Immunol 13 (2022): 862764. [6] Junya Wang, Zhao Jia, Huifeng Dang, Jun Zou*. Meteorin-like/Meteorin-β upregulates proinflammatory cytokines via NF-κB pathway in grass carp Ctenopharyngodon idella. Dev Come Immunol, 127 (2022): 104289. [7] Yaxin Wu , Zhao Jia, Huifeng Dang , Hehe Xiao , Wenji Huang , Qin Liu, Kangyong Chen, Lei Zhang, Jun Zou and Junya Wang*. Molecular Characterization, Evolution and Expression Analysis of TNFSF14 and Three TNFSF Receptors in Spotted Gar Lepisosteus oculatus. Journal of Marine Science and Engineering 10 (2022), 1035. [8] Junya Wang, Wei Wang, Jiawen Xu, Zhao Jia, Qin Liu, Xiaozhen Zhu, Chun Xia*, Jun Zou*. Structural insights into the co-evolution of IL-2 and its private receptor in fish. Dev Comp Immunol 115 (2020), 103895. [9] Xinyu Jiang#, Junya Wang#, Shuai Wan, Yujie Xue, Zhaosheng Sun, Xingxing Cheng, Qian Gao*, Jun Zou*. Distinct expression profiles and overlapping functions of IL-4/13A and IL-4/13B in grass carp (Ctenopharyngodon idella), Aquaculture and Fisheries 5 (2020), 72-79. [10] Junya Wang, Nianzhi Zhang, Zhenbao Wang, Yanan wu, Lijie Zhang, Chun Xia*. Structural insights into the evolution feature of a bony fish CD8alphaalpha homodimer. Mol Immunol 97 (2018) 109-116. 其它发表论文： [1] Wenji Huang, Xin Zhao, Ning Ji, Jiahong Guo, Jianhua Feng, Kangyong Chen, Yaxin Wu, Junya Wang, Hao Feng, Jun Zou*. IRF2 cooperates with phosphoprotein of spring viremia of carp virus to suppress antiviral response in zebrafish, J Virol. 96 (2022) e0131422. [2] Bangjie Wang, Yuting Qin, Zhaosheng Sun, Xiaozhen Zhu, Zhao Jia, Kangyong Chen, D. Liu, Junya Wang, Jun Zou*. Production and characterization of monoclonal antibodies against grass carp CD4-1 and CD4-2, Aquaculture and Fisheries (2022). [3] Yaxin Wu, Yibin Yang, Huifeng Dang, Hehe Xiao, Wenji Huang, Zhao Jia, Xin Zhao, Kangyon Chen, Ning Ji, Jiahong Guo, Zhiwei Qin, Junya Wang, Jun Zou*. Molecular identification of Klebsiella pneumoniae and expression of immune genes in infected spotted gar Lepisosteus oculatus, Fish Shellfish Immunol 119 (2021) 220-230. [4] Zhaosheng Sun, Yuting Qin, Danjie Liu, Bangjie Wang, Zhao Jia, Junya Wang, Qian Gao*, Jun Zou*, Yue Pang*. The evolution and functional characterization of CXC chemokines and receptors in lamprey, Dev Comp Immunol 116 (2021) 103905. [5] Kangyong Chen, Jiayin Tian, Junya Wang, Zhao Jia, Qin Zhang, Wenji Huang, Xin Zhao, Zhipeng Gao, Qian Gao, Jun Zou*. Lipopolysaccharide-induced TNFα factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio, Gene 780 (2021) 145487. [6] Yuting Qin, Zhaosheng Sun, Wei Wang, Jiawen Xu, Bangjie Wang, Zhao Jia, Xia Li, Junya Wang, Qian Gao, Xinhua Chen, Jun Zou*. Characterization of CD3γ/δ+ cells in grass carp (Ctenopharyngodon idella), Dev Comp Immunol 114 (2021) 103791. [7] Wei Wei, Junya Wang, Qingyu Min, Zhao Jia, Kangyuong Chen, Hao Feng, Jun Zou*. CCL19 variants mediate chemotactic response via CCR7 in grass carp Ctenopharyngodon idella, Dev Comp Immunol 122 (2021) 104127. [8] Zhao Jia, Junya Wang, Kangyong Chen, Qin Zhang, Zhaosheng Sun, Zeinab Hassan, Hao Feng, Jun Zou*. Identification and expression analysis of group II C-type lectin domain containing receptors in grass carp Ctenopharyngodon idella, Gene 789 (2021) 145668. [9] Zeinab Hassan, Junya Wang, Yuting Qin, Wei Wang, Qin Liu, Lina Lei, Zhaosheng Sun, Yibin Yang, Kaizheng Wu, Xiaozhen Zhu, Zixuan Wang, Hao Feng, Jun Zou*. Functional characterization of an interleukin 20 like homologue in grass carp Ctenopharyngodon idella, Fish Shellfish Immunol 115 (2021) 43-57. [10] Wei Wang, Junya Wang, Lina Lei, Jiawen Xu, Yuting Qin, Qian Gao*, Jun Zou* Characterisation of IL-15 and IL-2Rβ in grass carp: IL-15 upregulates cytokines and transcription factors of type 1 immune response and NK cell activation, Fish Shellfish Immunol 107 (Pt A) (2020) 104-117. [11] Yibin Yang, Junya Wang, Jiawen Xu, Qin Liu, Zixuan Wang, Xiaozhen Zhu, Xiaohui Ai, Qian Gao, Xinhua Chen, Jun Zou*. Characterization of IL-22 bioactivity and IL-22-positive cells in grass carp Ctenopharyngodon idella, Front Immunol 11 (2020) 586889. [12] Chang Zhang, Qin Zhang, Junya Wang, Jiayin Tian, Yunjie Song, Haixia Xie, Mingxian Chang, Pin Nie, Qian Gao*, Jun Zou*. Transcriptomic responses of S100 family to bacterial and viral infection in zebrafish, Fish Shellfish Immunol 94 (2019) 685-696. [13] Yujie Xue, Xinyu Jiang, Jingduo Gao, Xia Li, Jiawen Xu, Junya Wang, Qian Gao* Jun Zou*. Functional characterization of interleukin 34 in grass carp Ctenopharyngodon idella, Fish Shellfish Immunol 92 (2019) 91-100. [14] 季宁，魏伟，郭家鸿，王俊亚，李耀国，肖调义，邹钧. 草鱼呼肠孤病毒VP7蛋白单克隆抗体的制备与应用[J]. 水生生物学报，2022，46(9)：1293−1300 [15] 刘琴，贾钊，陈康勇，朱晓真，王梓璇，陈静，王俊亚，李耀国，肖调义，邹钧，草鱼IL-10单克隆抗体的制备与鉴定[J].水生生物学报，2022，46(12)：1867-1875. [16] 王梓璇，贾钊，邬恺正，朱晓真，王俊亚，冯浩，邹钧，草鱼IFNa和IFNd重组蛋白表达、纯化及单克隆抗体制备[J]. 水产学报，2022，46(11)：1−13 [17] 朱晓真，王俊亚，贾钊，王梓璇，王邦杰，邹钧，草鱼Ⅱ型干扰素的单克隆抗体制备与鉴定[J].水产学报，2022，46(8)：1487−1498 [18] 邹钧，邬恺正，王俊亚，范丁月，李仕然，徐兢，王梓璇，草鱼芳香烃受体ahr1a基因克隆、表达及进化分析[J].上海海洋大学学报，2023，32(1)：40-52.