个人简介
朱剑明，性别：男，学位：博士
教育经历：
2004年毕业于上海师范大学化学系
2010年至2016年硕博连读就读于中国科学院上海药物研究所，药物设计学专业。
工作经历：
2004年至2007年上海特化医药科技有限公司——药物合成研究员。
2007年至2010年桑迪亚医药技术(上海)有限责任公司——药物合成研究员。
2016年至2017年桑迪亚医药技术(上海)有限责任公司——药物合成高级研究员。
2017年至今上海第二工业大学——讲师。
主讲课程：化学与人类生活，细胞分子与生命
所获荣誉：
2017年12月第九期上海市属高校师资培训数字故事班级一等奖
2017年12月上海第二工业大学文理学部教师技能大赛优胜奖
近期论文
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Jianming Zhu,† Xiaolong Li,† Guimin Wang, Bo Li,* Zhijian Xu, Shikai Tian, Adrian Hall, Jinshan Shen, Jiye Shi,* Weiliang Zhu*. Facile Synthesis of Substituted 4-Alkoxy-2-oxazolines and Exploration of the Reaction Mechanism.Synthesis, 2016 ,48, 1331-1343 (IF: 2.652)；
Zhixin Zhao,† Jianming Zhu,† (共同一作) Haitian Quan, Guimin Wang, Bo Li, Weiliang Zhu, Chengying Xie, Liguang Lou. X66, a novel N-terminal heat shock protein 90 inhibitor, exerts antitumor effects without induction of heat shock response.Oncotarget, 2016, 7, 29648 - 29663 (IF: 6.359)；
Gui-min WANG,† Xiang WANG,† Jian-ming ZHU,† (共同一作) Bin-bin GUO, Zhuo YANG, Zhi-jian XU, Bo LI, He-yao Wang*, Ling-hua MENG*, Wei-liang Zhu*, Jian DING.. Docking-Based Structural Splicing and Reassembly Strategy to Develop Novel Deazapurine Derivatives as Potent B-RafV600E inhibitors.Acta Pharmacologica Sinica,2017, received. (IF: 3.166)；
Tao Jiang,† Yuren Zhou,† Jianming Zhu,†(共同一作), Zhuxi Chen, Peng Sun, Qiang Zhang, Zhen Wang, Qiang Shao, Xiangrui Jiang*, Bo Li*, Heyao Wang*, Weiliang Zhu, Jingshan Shen. Design, Synthesis, and Pharmacological Evaluation of Highly Potent and Selective Dipeptidyl Peptidase-4 Inhibitors.Arch. Pharm. Chem. Life Sci. 2015,348, 399–407 (IF: 2.040)；
Yunfei Zhou,Jianming Zhu, Bo Li, Yong Zhang, Jia Feng, Adrian Hall, Jiye Shi, Weiliang Zhu. Access to different isomeric dibenzoxazepinones through copper-catalyzed C-H etherification and C-N bond construction with controllable Smiles rearrangement.Org. Lett. 2016,18, 380-383. (IF: 6.732)；
Tao Jiang,† Yuren Zhou,† Zhuxi Chen,† Peng Sun,Jianming Zhu, Qiang Zhang, Zhen Wang, Qiang Shao, Xiangrui Jiang, Bo Li, Kaixian, Chen, Hualiang, Jiang, Heyao Wang, Weiliang Zhu, Jingshan Shen*. Design, Synthesis, and Pharmacological Evaluation of Fused beta-Homophenylalanine Derivatives as Potent DPP-4 Inhibitors.ACS Med. Chem. Lett. 2015,6, 602-606. (IF: 3.355)；
Zhijian Xu,† Guirui Yan,† Gaihong Wang, Bo Li,Jianming Zhu, Peng Sun, Xiaodong Zhang, Cheng Luo, Heyao Wang*, Weiliang Zhu. Combining pharmacophore, docking and substructure search approaches to identify and optimize novel BRAFV600E inhibitors. Bioorg. Med. Chem. Lett. 2012,22, 5428-5437. (IF: 2.486)；
Yuanyuan Gao,† Yong Zhang,† Jianming Zhu, Bo Li, Zhao Li, Weiliang Zhu, Jiye Shi, Qi Jia, Yiming Li*. Recent progress in natural products as DPP-4 inhibitors.Future Med. Chem. 2015,7, 1079-1089. (IF: 3.345)；
Li, Bo; Xue, Susu; Yang, Yang; Feng, Jia; Liu, Peng; Zhang, Yong; Zhu, Jianming; Xu, Zhijian; Hall, Adrian; Zhao, Bo; Shi, Jiye; Zhu, Weiliang. Regioselectivity and Mechanism of Synthesizing N-Substituted 2-Pyridones and 2-Substituted Pyridines via Metal-Free C-O and C-N Bond-Cleaving of Oxazoline[3,2-a]pyridiniums.Scientific Reports, 2017,7, 41287. (IF: 5.228)；
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