蔡仁 - 湖南大学 - 材料科学与工程学院

个人简介

蔡仁，男，毕业于美国佛罗里达大学，获分析化学博士学位，师从谭蔚泓教授。现任湖南大学材料科学与工程学院教授，博士生导师。目前，主要从事分子检测、分子医学和生物传感器等研究。在生物分子检测，疾病诊疗和生物传感器领域，至今发表SCI学术论文60余篇，其中包括在J. Am. Chem. Soc.，Anal. Chem. 等国际顶级学术期刊发表第一作者或通讯作者论文40篇，相关研究成果被C&EN等知名媒体所报道。获得湖南省自然科学基金优秀青年基金资助。另外，兼任Collagen and Leather杂志青年编委。教育背景 2013—2017 佛罗里达大学 (美国) 化学系博士工作履历 2019.4— 2019.10 访问研究员，佛罗里达大学 (美国) 化学系 2019.1— 2019.3 博士后研究员，西北太平洋国家实验室 (美国) 材料科学研究室 2018.10— 2019.1 访问研究员，基础科学研究所 (韩国蔚山) 软体和活性材料研究中心 2018.1— 2018.12 博士后研究员，佛罗里达大学 (美国) 化学系 2011.8—2013.8 研究助理，南洋理工大学 (新加坡) 材料科学与工程学院

研究领域

新型分析检测技术纳米诊疗剂的设计及肿瘤治疗生物传感器

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

学术成果 Publications 41. Futing Wang, Ren Cai,* Weihong Tan. Self-Powered Biosensor for a Highly Efficient and Ultrasensitive Dual-Biomarker Assay. Anal. Chem. 2023, 95, 14, 6046–6052. 40. Xing Li, Hongfen Yang,* Shaorong Lu,* Ren Cai.* A flexible strain sensor with high electrical conductivity, rapid electrothermal response, and high strain sensitivity for real-time monitoring of human joint movement. Advanced Materials Technologies 2023, https://doi.org/10.1002/admt.202300079. 39. Demiao Ma, Jia Ge,* Ang Wang, Jingxian Li, Hongfen Yang, Wenlei Zhai,* Ren Cai.* Ultrasensitive determination of a-glucosidase activity using CoOOH nanozymes and its application to inhibitor screening. Journal of Materials Chemistry B, 2023, 11, 2727 - 2732. 38. Jingxian Li, Song Wang, Hongfen Yang,* Run Li,* Ren Cai,* Weihong Tan. An “off-on” electrochemical luminescence biosensor with aggregation-induced emission for ultrasensitive detection of aflatoxin B1. Sensors and Actuators B: Chemical 2023, 13340, 380. 37. Chengyi Hong, Lingling Chen, Jiayi Huang, Yunling Shen, Hongfen Yang, Zhiyong Huang, Ren Cai,* Weihong Tan. Gold nanoparticle-decorated MoSe2 nanosheets as highly effective peroxidase-like nanozymes for total antioxidant capacity assay. Nano Research 2022, https://link.springer.com/article/10.1007/s12274-022-5328-9. 36. Fu-Ting Wang, Yang-Yang Hou, Xuecai Tan, Ke-Jing Huang,* Jing Xu,* Ren Cai.* Real-time multiple signal amplification self-powered biosensing platform for ultrasensitive detection of MicroRNA. Biosensors and Bioelectronics 2023, 222, 114933. 35. Jingxian Li, Hongfen Yang,* Ren Cai,* Weihong Tan. Ultra-Highly Sensitive Sandwich-Type Electrochemical Immunosensor for Selective Detection of Tumor Biomarkers. ACS Appl. Mater. Interfaces 2022, 14, 39, 44222–44227. 34. Chengyi Hong, Dandan Li, Siying Cao, Xin Huang, Hongfen Yang,* Dan Yang, Zhiyong Huang, Ren Cai,* Weihong Tan. Sensitive and multicolor detection of nitrite based on iodide-mediated etching of gold nanostars. Chem. Commun. 2022, 58, 12983–12986. 33. Jingxian Li, Ren Cai,* Weihong Tan. A Novel ECL Sensing System for Ultrahigh Sensitivity miRNA-21 Detection based on Catalytic Hairpin Assembly Cascade Nonmetallic SPR Effect. Anal. Chem. 2022, 94, 36, 12280–12285. 32. Zuocai Zhang,⊥ Tianyun Lu,⊥ Dan Yang, Shaorong Lu,* Ren Cai,* Weihong Tan. A Dual-function Sensor for Highly Sensitive Detection of Flame and Humidity. Small 2022, 18, 38, 2203334. 31. Jingxian Li, Mengyu Luo, Hongfen Yang, Chao Ma, Ren Cai,* Weihong Tan. Novel Dual-Signal Electrochemiluminescence Aptasensor Involving the Resonance Energy Transform System for Kanamycin Detection. Anal. Chem. 2022, 94, 16, 6410–6416. 30. Yadong Yang, Sujie Yang, Shudong Jiang, Mengru Liu, Xiuyu Liu, Gang Tang,* Ren Cai,* Weihong Tan. Facile synthesis of zinc-containing mesoporous silicate from iron tailings and enhanced fire retardancy of rigid polyurethane foam. Macromol. Mater. Eng. 2022, 307, 11, 2200586. 29. Jia Ge, Demiao Ma, Guohang Duan, Zhongyue Yan, Like Yang, Dan Yang, Ren Cai,* Weihong Tan. A novel probe for tetracyclines detection and its applications in cell imaging based on fluorescent WS2 quantum dots. Analytica Chimica Acta 2022, 1221, 340130. 28. Chengyi Hong, Jingjing Wang, Yuying Wang, Zhiyong Huang, Hongfen Yang,* Dan Yang, Ren Cai,* Weihong Tan. Fluorescence detection of milk allergen β-lactoglobulin based on aptamer and WS2 nanosheets. J. Mater. Chem. B 2022, 10, 6752 - 6757. 27. Jingxian Li, Mengyu Luo, Can Jin, Penghui Zhang, Hongfen Yang,* Ren Cai,* Weihong Tan. Plasmon-Enhanced Electrochemiluminescence of PTP Decorated Eu-MOF-Based Pt-Tipped Au Bimetallic Nanorods for Lincomycin Assay. ACS Appl. Mater. Interfaces 2022, 14, 1, 383–389. 26. Hao Fu, Dan Yang, Di Qiu, Chun-Hua Yan, Ren Cai,* Yaping Du,* Weihong Tan. Highly Stable 3D Supercuboids to 2D ZnSe Nanosheets: Forming for A High-Efficient Catalysis System. J. Phys. Chem. Lett. 2022, 13, 1855–1862. 25. Zuocai Zhang,⊥ Tianyun Lu,⊥ Dan Yang,* Shaorong Lu,* Ren Cai,* Weihong Tan. A high-wet-strength biofilm for readable and highly sensitive humidity sensors. Nano Lett. 2021, 21, 21, 9030–9037. 24. Kuo Liu, Dan Yang,* Hongfen Yang,* Shaorong Lu,* Ren Cai,* Weihong Tan. Multifunctional shape memory films for a flexible electrical sensor, Macromol. Mater. Eng. 2021, 306, 12, 2100580. 23. Ren Cai, Huandong Xiang, Dan Yang, Keng-Te Lin, Yuanzheng Wu, Ruyi Zhou, Zhanjun Gu, Liang Yan,* Yuliang Zhao,* Weihong Tan.* Plasmonic AuPt@CuS heterostructure with enhanced synergistic efficacy for radiophotothermal therapy. J. Am. Chem. Soc. 2021,143, 39, 16113–16127. 22. Chengyi Hong, Lingling Chen, Chenyue Wu, Dan Yang, Jia-Yong Dai, Zhiyong Huang, Ren Cai,* Weihong Tan. Green synthesis of Au@WSe2 hybrid nanostructures with the enhanced peroxidase-like activity for sensitive colorimetric detection of glucose. Nano Research 2022, 15, 1587–1592. 21. Zuocai Zhang, Dan Yang, Shaorong Lu,* Ren Cai,* Weihong Tan. Rapid Water-responsive Shape Memory Films for Smart Resistive Bending Sensors, Nano Today 2021, 38, 101202. 20. Chengyi Hong, Xiaoxia Zhang, Sishi Ye, Hongfen Yang,* Zhiyong Huang,* Dan Yang,* Ren Cai,* Weihong Tan. Aptamer-Pendant DNA Tetrahedron Nanostructure Probe for Ultrasensitive Detection of Tetracycline by Coupling Target-Triggered Rolling Circle Amplification. ACS Appl. Mater. Interfaces 2021, 13, 17, 19695–19700. 19. Zuocai Zhang, Dan Yang, Hongfen Yang, Yuqi Li, Shaorong Lu,* Ren Cai,* Weihong Tan. A hydrophobic sisal cellulose microcrystal film for fire alarm sensors. Nano Lett. 2021, 21, 5, 2104–2110. 18. Jia Ge, Jian-Hua Yu, Hongfen Yang,* Dan Yang,* Ren Cai.* Human serum albumin templated MnO2 nanosheets as an efficient biomimetic oxidase for biomolecule sensing. J. Mater. Chem. B 2020, 8, 11090-11095. 17. Chengyi Hong, Xiaoxia Zhang, Chenyue Wu, Qin Chen, Hongfen Yang,* Dan Yang,* Zhiyong Huang, Ren Cai,* Weihong Tan.* On-Site Colorimetric Detection of Cholesterol Based on Polypyrrole Nanoparticles. ACS Appl. Mater. Interfaces 2020, 12 (49), 54426-54432. 16. Jia Ge, Yun Hu, Ruijie Deng, Zhaohui Li, Kaixiang Zhang, Muling Shi, Dan Yang,* Ren Cai,* Weihong Tan.* Highly sensitive microRNA detection by coupling nicking-enhanced rolling circle amplification with MoS2 quantum dots. Anal. Chem. 2020, 92, 19, 13588–13594. 15. Ren Cai, Haiyan Jin, Dan Yang, Keng-Te Lin, Jianke Sun, Zhuo Chen, Xiaobing Zhang, Weihong Tan.* Generalized Preparation of Au NP@Ni(OH)2 Yolk-Shell Nanoparticles and Their Superior Catalytical Activity for Oxygen Evolution Reaction. Nano Energy 2020, 104542. 14. Ren Cai, Dan Yang, Xigao Chen, Yifan Lyv, He Zhen, Kangfu Chen, Yu Yang, Liqin Zhang, Jia Ge, Lian Xia, Yuliang Zhao, Weihong Tan.* 3D Halos Assembled from Fe3O4/Au NPs with Enhanced Catalytic and Optical Properties. Nanoscale 2019,11 (43), 20968-20976. 13. Ren Cai, Yaping Du, Dan Yang, Guohua Jia, Bowen Zhu, Yifan Lyu, Liping Qiu, Xigao Chen, Dechao Chen, Wei Chen, Liqin Zhang, Meng Luo,Lu Yang, Yuliang Zhao, Weihong Tan.* Free-standing 2D nanorafts by assembly of 1D nanorods for biomolecule sensing. Nanoscale 2019,11, 12169-12176. 12. Ren Cai, Dan Yang, Yifan Lyu, Bowen Zhu, Zhen He, Yusuke Kitamura, Liping Qiu, Xigao Chen, Yuliang Zhao, Zhuo Chen,* Weihong Tan.* Generalized preparation of 2D quasi-nanosheets via self-assembly of nanoparticles. J. Am. Chem. Soc. 2019, 141, 1725-1734. 11. Ren Cai, Dan Yang, Liang Yan, Feng Tian, Jichao Zhang, Yifan Lyv, Kangfu Chen, Chengyi Hong, Xigao Chen, Yuliang Zhao, Zhuo Chen, Weihong Tan.* Free-floating 2D Nanosheets With Superlattice Assembled From Fe3O4 Nanoparticles. ACS Appl. Nano Mater. 2018, 1 (10), 5389-5395. 10. J. Ge,# Ren Cai,# L. Yang, L. Zhang, Y. Jiang, Y. Yang, C. Cui, S. Wan, X. Chu, Weihong Tan.* Core-Shell HA-Au NPs@Si NPs Nanoprobe for Sensitive Fluorescence Hyaluronidase Detection and Cell Imaging. ACS Sustain. Chem. Eng. 2018, 6 (12), 16555-16562. 9. Ren Cai, D. Yang, X. Chen, Y. Huang, Y. Lyv, J. He, M. Shi, I-T. Teng, S. Wan, W. Hou, Weihong Tan.* Three Dimensional Multipod Superstructure based on Cu(OH)2 as a Highly Efficient Nanozyme. J. Mater. Chem. B 2016, 4, 4657-4661. 8. Ren Cai, D. Yang, L. Zhang, J. Wu, X. Chen, Z. Zhang, H. Huo, Q. Yan, Weihong Tan.* Fabrication of ultrathin Zn(OH)2 nanosheets as drug carriers. Nano Research 2016, 9, 2520–2530. 7. Ren Cai, D. Yang, L. Zhang, L. Qiu, H. Liang, X. Chen, Z. Zhang, S. Cansiz, S. Wan, Q. Yan, Weihong Tan.* A facile process for the preparation of three-dimensional (3D) hollow Zn(OH)2 nanoflowers at room temperature. Chem. Eur. J. 2016, 22(32): 11143-11147. 6. Ren Cai, D. Yang, S. Peng, X. Chen, Y. Huang, Y. Liu, W. Hou, S. Yang, Z. Liu, Weihong Tan.* Single Nanoparticle to 3D Supercage: Framing for an Artificial Enzyme System. J. Am. Chem. Soc. 2015, 137, 13957-13963. (C&EN NEWS, http://cen.acs.org/articles/93/web/2015/10/Tiny-Boxes-Hold-Catalytic-Surprise.html). 5. Ren Cai, Y. Du, S. Peng, H. Bi, W. Zhang, D. Yang, J. Chen, T. M. Lim, H. Zhang, Q. Yan.* The Synthesis of Porous Metal MCO3 (M=Mn, Co, Ca) Hollow Microstructures and Adsorption Property Thereof. Chem. Eur. J. 2014, 20(2): 421-425. 4. Ren Cai, J. Chen, D. Yang, Z. Zeng, S. Peng, J. Wu, W. Zhang, C. Zhu, T. -M. Lim, H. Zhang, Q. Yan.* Solvothermal-induced Conversion of One-Dimensional Multi-layer Nanotubes to Two-Dimensional Hydrophilic VOx Nanosheets: Synthesis and Water Treatment Application. ACS Appl. Mater. Interfaces 2013, 5(20): 10389-10394. 3. Ren Cai, Y. Du, W. Zhang, H. Tan, T. Zeng, X. Huang, H. Yang, C. Chen, H. Liu, J. Zhu, S. Peng, J. Chen, Y. Zhao, H. Wu, Y. Huang, R. Xu, T. -M. Lim, Q. Zhang, H. Zhang, Q. Yan.* Synthesis of Porous Amorphous FePO4 Nanotubes and Their Li Storage Properties. Chem. Eur. J. 2013, 19(5): 1568-1572. 2. Ren Cai, H. Li, W. Zhang, H. Tan, D. Yang, H. H. Hng, T. M. Lim, Q. Yan.* Controlled Synthesis of Double-wall a-FePO4 Nanotubes and Their LIB Cathode Properties. Small 2013, 9(7): 1036-1041. 1. Ren Cai, J. Chen, J. Zhu, C. Xu, W. Zhang, C. Zhang, W. Shi, H. Tan, D. Yang, H. H. Hng, T. M. Lim, Q. Yan.* Synthesis of CuxS/Cu Nanotubes and Their Lithium Storage Properties. J. Phys. Chem. C 2012, 116 (23), 12468-12474.

学术兼职

兼任Collagen and Leather杂志青年编委；Exploration杂志青年编委；Energies 杂志专题编辑(Topic Editor).