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个人简介

副教授,硕士生导师。2006年获得武汉大学理学硕士学位,2009年进入浙江大学化学系攻读博士学位并与2013年3月获得理学博士学位。2013年6月进入新加坡国立大学化学与生物分子工程系化学与生物分子工程系从事博士后研究工作(刘斌教授课题组)。2015年加入浙江工业大学

研究领域

主要研究方向是肿瘤纳米药物载体的构建,及其在肿瘤诊疗一体化和免疫治疗中的应用。通过高分子载体材料携载基因,化疗药以及具有光响应性的功能有机分子,构建多功能脂质纳米粒,应用于细胞和动物模型中肿瘤治疗研究。特色工作是通过仿生化构建,探讨细菌和光热刺激在肿瘤免疫治疗中的作用,解决肿瘤治疗中转移的难题。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Minjie Xu, Ling Li and Qinglian Hu*, The recent progress in photothermal-triggered bacterial eradication, Biomater. Sci., 2021, 9(6):‏ 1995-2008. (IF=6. 8) Yuming Yang, Minjie Xu, zhe Wang, Yanqing Yang, Jie Liu*, Qinglian Hu*, Lin Li and Wei Huang*, Immune remodeling triggered by photothermal therapy with semiconducting polymer nanoparticles in combination with chemotherapy to inhibit metastatic cancers. J. Mater. Chem. B, 2021, 9 (11):2613-2622 (IF=6.3) Qinglian Hu, Zemin Huang, Yukun Duan, Zhengwei Fu*, Bin Liu* Reprogramming Tumor Microenvironment with Photothermal Therap. Bioconjug. Chem., 2020, 31(5):1268-1278. (IF=4.349) Yanqing Yang#, Xiaoxiao Fan#, Ling Li#, Yuming Yang, Alifu Nuernisha, Dingwei Xue, Chao He, Jun Qian*, Qinglian Hu*(共同通讯), Hao Chen*, Jie Liu*, Wei Huang. Semiconducting Polymer Nanoparticles as Theranostic System for Near-Infrared-II Fluorescence Imaging and Photothermal Therapy under Safe Laser Fluence. ACS Nano. 2020, 14(2):2509-2521. (IF = 15.8, 高被引论文,JCR Q1, 中科院大类一区) Bing Guo#, Zemin Huang#, Qi Shi, Eshu Middha, Shidang Xu, Ling Li, Min Wu, Jianwen Jiang, Qinglian Hu*(共同通讯), Zhengwei Fu*, Bin Liu* Organic Small Molecule Based Photothermal Agents with Molecular Rotors for Malignant Breast Cancer Therapy, Adv. Funct. Mater., 2020, 30(5):1907093. (IF = 18.8, JCR Q1, 中科院大类一区) Zhe Wang#, Bing Guo#, Eshu Middha, Zemin Huang, Qinglian Hu*(共同通讯), Zhengwei Fu*, Bin Liu*, Microfluidics-Prepared Uniform Conjugated Polymer Nanoparticles for Photo-Triggered Immune Microenvironment Modulation and Cancer Therapy. ACS App. Mater. Interfaces, 2019, 11(12): 11167-11176. (IF = 9.4, JCR Q1) Qinglian Hu#, Min Wu#, Chun Fang, Changyong Cheng, Mengmeng Zhao, Weihuan Fang, Paul K. Chu, Yuan Ping*, Guping Tang*, Engineering nanoparticle-coated bacteria as oral DNA vaccines for cancer immunotherapy, Nano Letters, 2015, 8; 15(4):2732-2739. (IF = 11.189, JCR Q1, 中科院大类一区) Qinglian Hu#, Meng Gao#, Guangxue Feng, Bin Liu*, Mitochondria-Targeted Cancer Therapy Using a Light-up Probe With Aggregation-induced Emission Characteristics, Angew. Chem.-Int. Edit., 2014, 53(51), 14225-14229. (IF = 15.336, 高被引论,JCR Q1, 中科院大类一区) Qinglian Hu, Jinlei Wang, Jie She, Min Liu, Xue Jin, Guping Tang*, Paul K Chu*, Intracellular pathways and nuclear localization signal peptide-mediated gene transfection by cationic polymeric nanovectors, Biomaterials, 2012;33:1135-1145. ((IF = 12.475, JCR Q1, 中科院大类一区) Q.L. Hu#, Q.Y. Jiang#, X. Jin, J. Shen, K. Wang, Y.B. Li, F.J. Xu*, G.P. Tang*, Z.H. Li, Cationic microRNA-delivering nanovectors with bifunctional peptides for efficient treatment of pancreatic cancers, Biomaterials, 2013; 34 (9):2265-2276. ((IF = 12.475, JCR Q1, 中科院大类一区) Qinglian Hu#, Wen Li#, Xiurong Hu, Qida Hu, Jie Shen , Xue Jin , Jun Zhou , Guping Tang*, Paul K. Chu*, Synergistic treatment of ovarian cancer by co-delivery of survivin shRNA and paclitaxel via supramolecular micellar assembly. Biomaterials, 2012; 33: 6580-6591. (IF = 12.475, JCR Q1, 中科院大类一区) Qinglian Hu#, Meng Gao#, Guangxue Feng, Xiaodong Chen, Bin Liu*, A Cell Apoptosis Probe Based on Fluorogen with Aggregation-induced emission Characteristics, ACS Appl. Mat. & Inter., 2015, 7(8), 4875–4882. ((IF = 9.4, JCR Q1) Chongjing Zhang#, Qinglian Hu#, Guangxue Feng, Ruoyu Zhang, Youyong Yuan, Xianmao Lu, Bin Liu*,Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation induced emission characteristics. Chem. Sci.,2015,6 (8) ,4580-4586. (IF = 9.825, JCR Q1, 中科院大类一区) Meng Gao#, Qinglian Hu#(共同一作), Guangxue Feng, Nikodem Tomczak , Rongrong Liu, Bengang Xing, Ben Zhong Tang, Bin Liu*, A multifunctional probe with aggregation-Induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells, Adv. Healthc. Mat., 2015, 4(5):659-663. (IF = 6.27, JCR Q1) Gao Meng#, Hu Qinglian#(共同一作), Guangxue Feng,Benzhong Tang, Liu Bin. Fluorescentlight-up probe with “AIE + ESIPT” characteristics for specific detection of lysosomal esterase. Journal of Materials Chemistry B. 2014, 2, 3438. (IF=6.3, JCR Q1,封面文章)

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