个人简介
讲授课程:
《细胞生物学》
科研情况项目情况:
1.国家自然科学基金-青年科学基金:2018.01-2020.12,HDAC6调控巨噬细胞和中性粒细胞向炎症部位浸润的分子机理研究,31701216,25万,主持
2.山东省自然科学基金-面上项目:2017.07-2020.06,细胞骨架动态性重塑对免疫吞噬细胞趋化运动的调节及机制研究,ZR2017MC008,18万,主持
研究领域
1.细胞骨架与人类疾病
2.细胞动态结构成像与功能分析
3.核酸和多肽药物开发
近期论文
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1.YanB#,XieS#*,LiuY#,LiuW,LiD,LiuM,LuoHR,ZhouJ*.Histonedeacetylase6modulatesmacrophageinfiltrationduringinflammation.Theranostics.2018;8(11):2927-2938.2.XieS,OgdenA,AnejaR,ZhouJ*.Microtubule-BindingProteinsasPromisingBiomarkersofPaclitaxelSensitivityinCancerChemotherapy.MedResRev.2016;36(2):300-12.3.Tala#,XieS#,SunX#,SunX,RanJ,ZhangL,LiD,LiuM,BaoG*,ZhouJ*.Microtubule-associatedproteinMdp3promotesbreastcancergrowthand
metastasis.Theranostics.2014;4(10):1052-61.4.LiD#,XieS#,RenY#,HuoL,GaoJ,CuiD,LiuM,ZhouJ.Microtubule-associateddeacetylaseHDAC6promotesangiogenesisbyregulatingcellmigrationinanEB1-dependentmanner.ProteinCell.2011;2(2):150-60.5.XieS#*,YanB#,FengJ,WuY,HeN,SunL,ZhouJ,LiD,LiuM*.Alteringmicrotubulestabilityaffectsmicrotubuleclearanceandnuclearextrusionduringerythropoiesis.JCellPhysiol.2019;234(11):19833-19841.6.XieS*,WuY,HaoH,LiJ,GuoS,XieW,LiD,ZhouJ,GaoJ,LiuM*.CYLDdeficiencypromotespancreaticcancerdevelopmentbycausingmitoticdefects.JCellPhysiol.2019;234(6):9723-9732.7.XieS#,YangY#,LinX#,ZhouJ,LiD,LiuM*.CharacterizationofanovelEB1acetylationsiteimportantfortheregulationofmicrotubuledynamicsandcargorecruitment.JCellPhysiol.2018;233(3):2581-2589.8.XieS#,ChenM#,GaoS,ZhongT,ZhouP,LiD,ZhouJ,GaoJ*,LiuM*.TheB-boxmoduleofCYLDisresponsibleforitsintermolecularinteractionandcytoplasmiclocalization.Oncotarget.2017;8(31):50889-50895.9.XieS#,DongB#,SunX,Tala,HeX,ZhouJ,LiuM,LiD.Identificationofacytoplasmiclinkerproteinasapotentialtargetforneovascularization.Atherosclerosis.2014;233(2):403-9.10.XieS#,QinJ#,LiuS,ZhangY,WangJ,ShiX,LiD,ZhouJ,LiuM*.Cep70overexpressionstimulatespancreaticcancerbyinducingcentrosomeabnormalityandmicrotubuledisorganization.SciRep.2016;6:21263.