个人简介
教学情况
《细胞生物学》、《神经生物学》、《遗传学与细胞生物学实验》
科研项目
1、国家自然科学基金委员会,青年科学基金项目,31900694,线粒体锚定蛋白连接酶MAPL介导的线粒体分裂在阿尔茨海默病中的分子机理研究,2020.01-2022.12,24万元,在研,主持。
2、青岛市博士后应用研究项目资助,2015147,线粒体分裂蛋白MAPL在心肌肥大中的作用,5万元,已结题,主持。
3、国家自然科学基金委员会,面上项目,81371466,神经甾体脱氢表雄酮和孕酮在应激诱发的吗啡条件性位置偏爱中的作用及机制,2014-01至2017-12,70万元,已结题,参与。
4、国家自然科学基金委员会,重大研究计划,91332204,基底外侧杏仁核多巴胺D1受体介导环境线索提取药物戒断记忆的神经环路,2014-01-至2017-12,300万元,已结题,参与。
研究领域
1.干细胞及其产品在各种适应症中的应用;2.探寻神经退行性疾病、心血管疾病的药物靶点。
近期论文
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1. YFZhao*,YY Liu,QL Zhang, HL Liu, JN Xu.The Mechanism Underlying the Regulation of Long Non-coding RNA MEG3 in Cerebral Ischemic Stroke.Cell Mol Neurobiol,2022 Jan 6.2. YFZhao*, HLLiu, QLZhang, Y Zhang. The functions of long non-coding RNAs in neural stem cell proliferation and differentiation. Cell and bioscience,
2020 May 29;10:74.3. YFZhao*, Y Zhang, L Zhang,YH Dong, HFJi, L Shen.The Potential Markers of Circulating microRNAs and long non-coding RNAs in Alzheimer's Disease, Aging and Disease,2019 Dec 1;10(6):1293-1301.4.YF Zhao#, JF Zhang#,HL Yang#,DY Cui,JJ Song, QQ Ma, WJ Luan,B Lai, L Ma,M Chen*,PZheng*.Memory retrieval in addiction: a role for miR-105-mediated regulation of D1 receptors in mPFC neurons projecting to the basolateral amygdala.BMC biology, 2017 Dec 27; 15(1):128.5. YFZhao,MPonnusamy,CY Liu, JTian,YH Dong, JN Gao,CQ Wang, Y Zhang,L Zhang, K Wang*, PF Li*.MiR-485-5p modulates mitochondrial fission through targeting mitochondrial anchored protein ligase in cardiac hypertrophy, Biochim Biophys Acta Mol Basis Dis,2017 Nov,1863(11):2871-2881.6. YFZhao,M Ponnusamy, LZhang, Y Zhang, CY Liu, K Wang*, PF Li*.The role of MiR-214 in cardiovascular diseases, European journal of pharmacology, 2017 Dec 5, 816:138-145.7.YF Zhao, MPonnusamy,YH Dong, L Zhang, K Wang*, PF Li*. Effects of miRNAson myocardial apoptosis by modulating mitochondria related proteins. Clin Exp Pharmacol Physiol, 2017 Apr; 44(4):431-440.8.Y Zhang, YF Zhao, X Ao, WP Yu, L Zhang, Y Wang, WGChang. The Role of Non-coding RNAs in Alzheimer's Disease: From Regulated Mechanism to Therapeutic Targets and Diagnostic Biomarkers. Front Aging Neurosci, 2021 Jul 2;13:654978.9.Y Zhang, YFZhao, Y Liu, M Wang, WPYu, L Zhang. Exploring the regulatory roles of circular RNAs in Alzheimer's disease. Transl Neurodegener,2020 Sep 21;9(1):35. 10. Y Zhang, YFZhao, L Zhang, WPYu, YWang, WGChang. Cellular Prion Protein as a Receptor of Toxic Amyloid-β42 Oligomers Is Important for Alzheimer's Disease. Front Cell Neurosci. 2019 Jul 30;13:339.