Kempe, Kristian - Monash University - Department of Materials Science and Engineering

个人简介

Biography 06/2012 - 07/2014 Alexander-von-Humboldt Fellow, Department of Chemical and Biomolecular Engineering, The University of Melbourne, and Monash Institute of Pharmaceutical Sciences, Monash University, Australia 08/2014 - 03/2016 Senior Research Fellow, Department of Chemistry, University of Warwick, United Kingdom 04/2016 - 07/2019 NHMRC-ARC Dementia Research Development Fellow, Group Leader, Monash Institute of Pharmaceutical Sciences, Monash University, External positions Senior Visiting Fellow, University of Warwick 2016 Honorary Fellow, University of Melbourne 2015

近期论文

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Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth Ma, Z., Wong, S. W., Forgham, H., Esser, L., Lai, M., Leiske, M. N., Kempe, K., Sharbeen, G., Youkhana, J., Mansfeld, F., Quinn, J. F., Phillips, P. A., Davis, T. P., Kavallaris, M. & McCarroll, J. A., Jun 2022, In: Biomaterials. 285, 17 p., 121539. A Guideline for the Synthesis of Amino-Acid-Functionalized Monomers and Their Polymerizations Leiske, M. N. & Kempe, K., Jan 2022, In: Macromolecular Rapid Communications. 43, 2, 24 p., 2100615. Heat-Induced Living Crystallization-Driven Self-Assembly: The Effect of Temperature and Polymer Composition on the Assembly and Disassembly of Poly(2-oxazoline) Nanorods Finnegan, J. R., Davis, T. P. & Kempe, K., May 2022, In: Macromolecules. 55, 9, p. 3650–3660 11 p. Hydrophobicity Regulates the Cellular Interaction of Cyanine5-Labeled Poly(3-hydroxypropionate)-Based Comb Polymers Mahmoud Mohamed, A., Nowell, C., Feeney, O., van 't Hag, L., Davis, T. P. & Kempe, K., 3 Aug 2022, (Accepted/In press) In: Biomacromolecules. 12 p. Lipidic poly(2-oxazoline)s as PEG replacement steric stabilisers for cubosomes Rajesh, S., Leiske, M. N., Leitch, V., Zhai, J., Drummond, C. J., Kempe, K. & Tran, N., Oct 2022, In: Journal of Colloid and Interface Science. 623, p. 1142-1150 9 p. Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)s Mazrad, Z. A. I., Lai, M., Davis, T. P., Nicolazzo, J. A., Thurecht, K. J., Leiske, M. N. & Kempe, K., 14 Aug 2022, In: Polymer Chemistry. 13, 30, p. 4436-4445 10 p. Zwitterionic Amino Acid-Derived Polyacrylates as Smart Materials Exhibiting Cellular Specificity and Therapeutic Activity Leiske, M. N., Mazrad, Z. A. I., Zelcak, A., Wahi, K., Davis, T. P., McCarroll, J. A., Holst, J. & Kempe, K., 13 Jun 2022, In: Biomacromolecules. 23, 6, p. 2374-2387 14 p. Biodegradable Polymeric Nanoparticles for Brain-Targeted Drug Delivery Kempe, K. & Nicolazzo, J. A., 2021, Nanomedicines for Brain Drug Delivery. Morales, J. O. & Gaillard, P. J. (eds.). New York NY USA: Humana Press, p. 1-27 27 p. (Neuromethods; vol. 157). Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: Toward enhanced monodispersity and stability Deepagan, V. G., Leiske, M. N., Fletcher, N. L., Rudd, D., Tieu, T., Kirkwood, N., Thurecht, K. J., Kempe, K., Voelcker, N. H. & Cifuentes-Rius, A., 2021, In: Nano Letters. 21, 1, p. 476–484 9 p. Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood Leiske, M. N., Lai, M., Amarasena, T., Davis, T. P., Thurecht, K. J., Kent, S. J. & Kempe, K., Jul 2021, In: Biomaterials. 274, 13 p., 120843. Intrinsic Green Fluorescent Cross-Linked Poly(ester amide)s by Spontaneous Zwitterionic Copolymerization Zia, A., Finnegan, J. R., Morrow, J. P., Yin, W., Jasieniak, J. J., Pentzer, E., Thickett, S., Davis, T. P. & Kempe, K., 8 Nov 2021, In: Biomacromolecules. 22, 11, p. 4794-4804 11 p. Nitrile-Functionalized Poly(2-oxazoline)s as a Versatile Platform for the Development of Polymer Therapeutics Mazrad, Z. A. I., Schelle, B., Nicolazzo, J. A., Leiske, M. N. & Kempe, K., 8 Nov 2021, In: Biomacromolecules. 22, 11, p. 4618-4632 15 p. Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions Pizzi, D., Mahmoud, A. M., Klein, T., Morrow, J. P., Humphries, J., Houston, Z. H., Fletcher, N. L., Bell, C. A., Thurecht, K. J. & Kempe, K., 15 May 2021, In: European Polymer Journal. 151, 9 p., 110447. Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s Finnegan, J. R., Pilkington, E. H., Alt, K., Rahim, M. A., Kent, S. J., Davis, T. P. & Kempe, K., 7 Jun 2021, In: Chemical Science. 12, 21, p. 7350-7360 11 p. Using 2-isopropyl-2-oxazine to explore the effect of monomer distribution and polymer architecture on the thermoresponsive behavior of copolymers Warne, N. M., Finnegan, J. R., Feeney, O. M. & Kempe, K., 15 Nov 2021, In: Journal of Polymer Science. 59, 22, p. 2783-2796 14 p. Advances and Opportunities of Oil-in-Oil Emulsions Zia, A., Pentzer, E., Thickett, S. & Kempe, K., 2 Sep 2020, In: ACS Applied Materials & Interfaces. 12, 35, p. 38845-38861 17 p. Cobalt-Directed Assembly of Antibodies onto Metal-Phenolic Networks for Enhanced Particle Targeting Zhang, W., Besford, Q. A., Christofferson, A. J., Charchar, P., Richardson, J. J., Elbourne, A., Kempe, K., Hagemeyer, C. E., Field, M. R., Mcconville, C. F., Yarovsky, I. & Caruso, F., 8 Apr 2020, In: Nano Letters. 20, 4, p. 2660-2666 7 p. Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo Walker, J. A-T., Wang, X., Peter, K., Kempe, K. & Corrie, S. R., 24 Apr 2020, In: ACS Sensors. 5, 4, p. 1190-1197 8 p. Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A Structure-Activity Comparison of Biodistribution Humphries, J., Pizzi, D., Sonderegger, S. E., Fletcher, N. L., Houston, Z. H., Bell, C. A., Kempe, K. & Thurecht, K. J., 20 Jul 2020, In: Biomacromolecules. 21, 8, p. 3318–3331 14 p. Next-generation polymeric nanomedicines for oncology: perspectives and future directions Fletcher, N. L., Kempe, K. & Thurecht, K. J., Sep 2020, In: Macromolecular Rapid Communications. 41, 18, 10 p., 2000319.