张春春 - 四川大学 - 分析测试中心

个人简介

个人背景 2004.8- 2009.2 新墨西哥大学化学与化学生物系生物化学和生物有机化学专业博士 2000.9-2003.6 四川大学化学学院有机化学专业硕士 1996.9-2000.6 西南师范大学化学化工学院化学专业学士

研究领域

1、酶催化反应动力学及结构研究 2、不对称生物催化合成 3、核磁共振及分子模拟在药物分子识别中的应用

近期论文

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1. Shanshan Wu, Chunchun Zhang, Ruyin Cao, Dingguo Xu and Hua Guo, pH- dependent Reactivity for Glycyl-L-Tyrosine in Carboxypeptidase A Catalyzed Hydrolysis, J. Phys. Chem. B (2011) submitted. 2. Shanshan Wu, Chunchun Zhang, Dingguo Xu and Hua Guo, Ester Hydrolysis Catalyzed by Carboxypeptidase A: Promoted Water vs Anhydride Pathways, J. Phys. Chem. B. 2010, 114, 9259-9267 3. Jianying Dai, Lorenzo Finci, Chunchun Zhang, Sushmita Lahiri, Guofeng Zhang, Ezra Peisach, Karen N. Allen, and Debra Dunaway-Mariano. The Coupling of Substrate Induced Cap Domain Closure with Placement of the General Base is Key to the Emergence of b-Phosphoglucomutase from the HAD Superfamily of Phosphatases. Biochemistry, 2009 (48) 1984–1995 4. Silvaggi NR, Zhang CC, Lu ZB, Dai JY, Dunaway-Mariano D, and Allen KN, The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a, J. Bio. Chem. 2006 (281) 14918-14926.