个人简介
教育背景
1974年生于中国成都
1992-1993 信阳陆军学院,军政训练
1993-1997 北京大学物理学系,获学士学位
1997-2000 北京大学物理学系凝聚态物理,获硕士学位
2000-2005 德国Ulm大学生物物理系,获博士学位
研究领域
1. 用核磁共振方法测定生物、有机分子的三维结构
2. 蛋白质的结构-动力学-功能关系
近期论文
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1. ‘Spectroscopy Study of Substrate Binding to the Carbonmonoxy Form of Dehaloperoxidase from Amphitrite ornata’, Nienhaus K, Deng P, Belyea J, Franzen S, Nienhaus GU, J. Phys. Chem. B 110,13264-13276 (2006).
2. ‘Probing Electric Fields in Protein Cavities by Using the Vibrational stark effect of Carbon Monoxide’, Hartwig Lehle, Jan M. Kriegl, Karin Nienhaus, Pengchi Deng, Stephanus Fengler, G. Ulrich Nienhaus, Biophys. J. 88, 1978-1990 (2005).
3. ‘ThrE11 regulates O2 affinity in Cerebratulus lacteus mini-hemoglobin’, Pesce A, Nardini M, Ascenzi P, Geuens E, Dewilde S, Moens L, Bolognesi M, Riggs AF, Hale A, Deng P, Nienhaus GU, Olson JS, Nienhaus K, J. Biol.Chem., 279(32), 33662-33672 (2004).
4. ‘Ligand Dynamics in a Protein Internal Cavity’, Kriegl JM, Nienhaus K, Deng P, Fuchs J, Nienhaus GU, Proc. Natl. Acad. Sci. USA, 100 (12), 7069- 7074 (2003).
5. ‘Structural dynamics of myoglobin: Ligand migration and binding in valine 68 mutants’, Nienhaus K, Deng P, Olson JS, Warren JJ, Nienhaus GU, J. Biol. Chem. 278(43), 42532-42544 (2003).
6. ‘Structural dynamics of myoglobin: spectroscopic and structural characterization of ligand docking sites in myoglobin mutant L29W’, Nienhaus K, Deng P, Kriegl JM, Nienhaus GU, Biochemistry, 42 (32), 9633-9646 (2003).
7. ‘Structural dynamics of myoglobin: effect of internal cavities on ligand migration and binding’, Nienhaus K, Deng P, Kriegl JM, Nienhaus GU, Biochemistry, 42 (32), 9647-9658 (2003).
8. ‘Ligand Binding and Protein Dynamics in Neuroglobin’, Kriegl JM, Bhattacharyya AJ, Nienhaus K, Deng P, Minkow O, Nienhaus GU, Proc. Natl. Acad. Sci. USA, 99, 7992-7997 (2002).
9. ‘The Effect of Ligand Dynamics on Heme Electronic Transitions in Myoglobin’, Nienhaus K, Lamb DC, Deng P, Nienhaus GU, Biophys. J. 82, 1059-1067 (2002).
10. ‘α-淀粉酶抑制剂AAI的核磁共振氢谱谱峰归属及结构分析’, 邓鹏翅, 吕善运, 罗静初, Sandor Pongor, 刘修才, 曲红, 梁宋平, 韩汝珊, 顾孝诚, 生物物理学报, 16 (3), 444-452 (2000).
11. ‘Solution structure of the major α-amylase inhibitor of the crop plant Amaranthus’, Lu S, Deng P, Liu X, Luo J, Han R, Gu X, Liang S, Wang X, Li F, Lozanov V, Patthy A, Pongor S, J. Biol. Chem. 274, 20473-20478 (1999).