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1.Liu, Yu#, Chen, C.#,Xu, Z.,Scuoppo, C., Rillahan, CD.,Gao,J., Spitzer, B., Bosbach, B., Kastenhubr, ER., Baslan, T., Ackermann, S., Cheng, L., Wang, Q., Niu, T., Schultz, N., Levine, RL., Mills, AA.& Lowe, SW., Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.Nature.2016,531:471-5.(#共同第一)
2.Ye, P.,#Liu, Yu,#Chen, C., Tang F., Wu Q., Wang X., Liu, CG., Liu, X., Liu, Y.*& Zheng, P.*, An mTORC1-Mdm2-Drosha Axis for miRNA Biogenesis in Response to Glucose- and Amino Acid-Deprivation.Molecular Cell.2015,57(4):708-720. (#共同第一)(*共同通讯)
3. Liu, Yu& Chang, A., Heat shock response relieves ER stress.EMBO J. 2008, 27(7):1049-1059
4. Liu, Yu& Chang, A., A mutant plasma membrane protein is stabilized upon loss of Yvh1, a novel ribosome assembly factor.Genetics.2009,181(3):907-915
5.Liu, Yu, Sitaraman, S., Chang, A., Multiple degradation pathways for misfolded mutants of the yeast plasma membrane ATPase, Pma1.J Biol Chem. 2006, 281(42):31457-31466
6.Liu, Yu, Chang, A., Quality control of a mutant plasma membrane ATPase: ubiquitylation prevents cell-surface stability.J Cell Sci. 2006,119:360-369
7.Chen, C.,Liu, Yu, Rappaport, AR., Kitzing, T., Schultz N., Zhao, Z., Shroff, AS., Dickins, R., Vakoc, Cr., Bradner, Je., Stock, W., LeBeau, MM., Shannon, KM.., Kogan, S., Zuber, J & Lowe, SW.MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.Cancer Cell. 2014, 25(5):652-665
8.Chen, C.,Liu, Yu, Lu, C., Cross, JR., Morris JP 4th, Shroff AS, Ward PS, Bradner JE, Thompson C & Lowe SW. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition.Gene Dev.2013, 27(18):1974-1985
9.Chen, C.,Liu, Yu, Liu,Y.* & Zheng, P.*, Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice.J Clin Invest. 2010, 120(11): 4091-4101(*共同通讯)
10.Chen, C.,Liu, Yu, Liu,Y.* & Zheng, P.*, mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.Sci Signal. 2009, 2(98):ra75 1-7(*共同通讯)
11.Chen, C.,Liu, Yu, Liu, R., Ikenoue, T., Guan, KL., Liu, Y.* & Zheng, P.*, TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species.J Exp Med. 2008,205:2397-2408(*共同通讯)
12.Wu, Q.,Liu, Yu, Chen, C., Ikenoue, T., Qiao, Y., Li, CS., Li, W., Guan, KL., Liu, Y.*, & Zheng, P.*, The Tuberous Sclerosis Complex-Mammalian Target of Rapamycin Pathway Maintains the Quiescence and Survival of Naive T Cells.J Immunol.. 2011, 187(3):1106-1112(*共同通讯)
13.Chen, C.,Liu, Yu, Liu, Y.* & Zheng, P.*, The axis of mTOR-mitochondria-ROS and stemness of the hematopoietic stem cells.Cell Cycle. 2009,8:1158-1160(*共同通讯)
14.Han, S.,Liu, Yu& Chang, A., Cytoplasmic Hsp70 promotes ubiquitination for ER-associated degradation of a misfolded mutant of the yeast plasma membrane ATPase, PMA1.J Biol Chem.2007, 282:26140-26149