李浇 - 四川大学 - 华西基础医学与法医学院

个人简介

李浇，副教授，硕士生导师,四川大学与美国俄亥俄州立大学联合培养博士。主持和主研多项国家自然科学基金，发表国际高质量论文10余篇。【主要承担项目】 1. 主持：国家自然科学基金-青年项目：《CyPA在杜氏利什曼原虫胞内寄生过程中的生物学功能研究》，批准经费30万元； 2. 主研：国家自然科学基金-面上项目：《西北干旱荒漠区利什曼原虫、白蛉和蜥蜴的协同进化研究》，批准经费69.6万，负责人：陈达丽。

研究领域

1.胞内寄生病原体免疫逃逸机制；2.胞内寄生病原体毒力相关基因的筛选及功能鉴定；3.胞内寄生病原体基因编辑。

近期论文

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1. Jinlei He, Fan Huang, Jianhui Zhang, Qiwei Chen, Zhiwan Zheng, Qi Zhou, Dali Chen,Jiao Li*, Jianping Chen*.Vaccine design based on 16 epitopes of SARS-CoV-2 spike protein.J Med Virol. 2021;93(4):2115 -2131. (IF: 20.693) 2. Zhiwan Zheng#,Jinlei He#,Tao Luo,Jianhui Zhang,Qi Zhou,Shuangshuang Yin,Dali Chen,Jie Luo,Jianping Chen*,Jiao Li*.Mutation Characteristics and Phylogenetic Analysis of FiveLeishmaniaClinical Isolates.Animals.2022, 12(3): 321. 3. Jianhui Zhang#,Jiao Li#, Kaifeng Hu#, Qi Zhou, Xiaoxiao Chen, Jinlei He,Shuangshuang Yin, Yangjian Chi, Xuechun Liao, Yuying Xiao, Hanxiao Qin,Zhiwan Zheng* and Jianping Chen*.Screening Novel Vaccine CandidatesforLeishmania DonovanibyCombining Differential Proteomicsand Immunoinform atics Analysis.2022. 4. Jianhui Zhang#,Jinlei He#,Xuechun Liao,Yuying Xiao,Chang Liang,Qi Zhou,Han Chen,Zhiwan Zheng,Hanxiao Qin,Dali Chen,Qiwei Chen,Jiao Li*,Jianping Chen*.Development of dominant epitope-based vaccines encoding Gp63, Kmp-11 and Amastin against visceral leishmaniasis,Immunobiology, 2021, 226(3): 152085. 5. Qi Zhou#,Jiao Li#, Xianguang Guo , Jinlong Liu , Qi Song , Xiong Gong , Han Chen, Jianhui Zhang, Jinlei He, Zhiwan Zheng, Dali Chen*, Jianping Chen*.Records of three mammal tick species parasitizing an atypical host, the multi-ocellated racerunner lizard, in arid regions of Xinjiang, China.Parasit Vectors. 2021;14(1):135. 6. Zhiwan Zheng, Jianping Chen, Guangxu Ma, Abhay R Satoskar,Jiao Li*. Integrative genomic, proteomic and phenotypic studies ofLeishmania donovanistrains revealed genetic features associated with virulence and antimony-resistance.Parasit Vectors. 2020;13(1):510. 7. ZhiWan Zheng#,Jiao Li#, Han Chen, Jin‑Lei He, Qi‑Wei Chen, Jian‑Hui Zhang, Qi Zhou, Da‑Li Chen*, Jian‑Ping Chen*. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosupp ressive derivative, dihydrocyclosporin A.Parasit Vectors. 2020;13(1):94. 8. Han Chen#,Jiao Li#, Junrong Zhang, Xianguang Guo, Jinlong Liu, Jinlei He, Qi Song, Jianhui Zhang, Minli Chen, Zhiwan Zheng, Dali Chen*, Jianping Chen*. Multi-locus characterization and phylogenetic inference ofLeishmaniaspp. in snakes from Northwest China.PLoS One. 2019;14(4): e0210681.