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个人简介

教育与工作经历 2009年9月-2013年6月,山西农业大学,动物科学,学士 2013年9月-2016年6月,山西农业大学,养殖,硕士 2016年9月-2019年9月,南京农业大学,动物遗传育种与繁殖,博士 2019年9月-至今,南京农业大学,动物科技学院,师资博后 承担科研项目 [1]国家自然科学青年基金,基于LH峰探究circRNA介导CITED4/CBP通路参与多胎湖羊卵泡发育的调控机制,32002174,2021/01-2023/12,主持 [2]中央高校基本科研业务费,基于LH峰探究circRNA介导CITED4/CBP通路参与多胎湖羊卵泡发育的调控机制,KJQN202130,2021/01-2021/12,主持 [3] 江苏省博士后基金,LncRNA-412.25作为ceRNA介导LIF/STAT3通路参与多胎湖羊卵泡发育调控机制的研究,2021K254B, 2021/05-2023/04,主持 [4] 国家自然科学面上基金,子宫内膜lncRNA与miRNA基于Wnt/β-catenin通路参与湖羊多胎调控机制的研究,32072728,2021/01-2024/12,第一参加人 [5] 国家自然科学面上基金,LncRNA与miRNA参与多胎湖羊卵泡发育精准调控机制研究,31872357,2019/01-2022/12,参加

研究领域

动物生殖调控;表观遗传修饰

动物遗传育种与繁殖

近期论文

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主要围绕多胎湖羊新品系的选育和特色性状关键基因挖掘开展研究工作。近五年代表作如下: [1] Xiaolei Yao, Xiaoxiao Gao, Yongjin Bao, M.A.EI-Samahy, Jinyu Yang, Zhibo Wang, Xiaodan Li, Guomin Zhang, Yanli Zhang, Wujun Liu, Feng Wang*. lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep[J]. Mol Ther-Nucl Acids, 2021, 24(4):223-240 (IF=8.886, Top10) [2] Xiaolei Yao, M A EI-Samahy, Shenhua Xiao, Zhibo Wang, Fanxing Meng, Xiaodan Li, Yongjin Bao, Yanli Zhang, Ziyu Wang, Yixuan Fan, Feng Wang*. CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro [J].Reproduction, 2021,161 255–267(IF=3.906) [3] Xiaolei Yao#, Zhibo Wang#, Xiaoxiao Gao, Xiaodan Li, Hua Yang, M.A. Ei-Samahy, Yongjin Bao, Shenhua Xiao, Fanxing Meng, Feng Wang*. Unconservative_15_2570409 suppresses progesterone receptor expression in the granulosa cells of Hu sheep. Theriogenology, 2020,157:303-313 (IF=2.740, Top20%) [4] Xiaolei Yao, Zhibo Wang, M.A. El-Samahy, Caifang Ren, Zifei Liu, Feng Wang*, Peihua You. Roles of vitamin D and its receptor in the proliferation and apoptosis of luteinised granulosa cells in the goat.Reproduction, Fertility and Development, 2020,32(3): 335-348(IF=2.311) [5] Xiaolei Yao, M.A.EI-Samahy, Lijie Fan, Linfeng Zheng, Yuyue Jin, Jing pang, Guomin Zhang, Zifei Liu, Feng Wang*. In vitro inflfluence of selenium on the proliferation of and steroidogenesis in goat luteinized granulosa cells. Theriogenology, 2018,114:70-80 (IF=2.299, Top10%) [6] Xiaolei Yao, M.A. EI-Samahy, Hua Yang Xu Feng, Fengzhe Li, Fanxing Meng, Haitao Nie, Feng Wang⁎. Age-associated expression of VDR and VD-metabolizing enzymes in the male reproductive tract and sperm of Hu sheep. Anim Reprod Sci, 2018,190:27-38(IF=1.817, Top20%) [7] Xiaolei Yao, Hua Yang, Yanli Zhang, Caifang Ren, Haitao Nie, Yixuan Fan, Wenjun Zhou, Shuting Wang, Xu Feng, Feng Wang*. Characterization of GALNTL5 gene sequence and expression in ovine testes and sperm. Theriogenology, 2017, 95: 54-61(IF=2.136, Top10%) [8] Xiaolei Yao, Guomin Zhang, Yixuan Guo, Mohamed EI-Samahy, Shuting Wang, Yongjie Wan, Le Han, Zifei Liu, Feng Wang, Yanli Zhang*. VD receptor expression and potential role of VD on cell proliferation and steroidogenesis in goat ovarian GCs. Theriogenology, 2017, 102: 162-173(IF=2.136, Top10%) [9] Xiaolei Yao, M.A. EI-Samahy, Xu Feng, Tinging Zhang, Fengzhe Li, Guomin Zhang, Jing Pang, Haitao Nie, Feng Wang*. Expression and localization of GALNTL5 in the reproductive organs and sperm of Hu sheep. Anim Reprod Sci, 2017,187:159-16(IF=1.647) [10] 姚晓磊, 黄欣爱, 肖慎华, 郑临枫, 范丽洁, 金宇月, 刘孜斐, 张艳丽, 王 洁, 王 锋*. 不同发育阶段湖羊生殖器官脂联素受体与睾酮分泌关键基因表达模式及相关性研究.畜牧兽医学报, 2018, 49(8):1642-1650. [11] 姚晓磊, 孟繁星, 王书婷, 刘孜斐, 王锋*. GALNTL5基因在不同月龄湖羊附睾中的表达模式及其miRNA的预测. 南京农业大学学报, 2019,42(3):519-525.

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