个人简介
教育与工作经历
2009/09-2013/06 安徽农业大学 动物科学 学士
2013/09-2018/09 南京农业大学 动物遗传育种与繁殖 农学博士
2018/12--，南京农业大学 动物科技学院 师资博士后
奖励及荣誉
第十九届中国畜牧兽医学会动物繁殖学分会优秀论文
参加学术团体及任职情况
Biology of Reproduction, Theriogenology, Frontiers in cell and developmental biology审稿人
承担科研项目
1. 国家自然科学基金委员会，青年科学基金项目，32102546，LncRNA-loc102177005通过RNA结合蛋白YTHDF2调控山羊合子基因组激活的机制研究，2022/01至2024/12，24万元，在研，主持
2. 江苏省基础研究计划（自然科学基金）-青年基金，LncRNA lnc-2217对山羊合子基因组激活的表观遗传调控机制研究，2020/07-2023/06，20万，在研，主持
3. 中国博士后科学基金，Lnc-3712靶向Kdm5b调控山羊核移植胚胎重编程的研究，2019/07-2021/06，8万，在研，主持
4. 国家自然科学基金面上项目，m6A甲基化修饰参与调控山羊体细胞核移植胚胎母源-合子转换期重编程的研究，2020/1-2023/12，59万，在研，参加
5. 国家自然科学基金面上项目，LncRNA通过激活TGFβ/SMAD2信号通路调控湖羊垂体促性腺激素分泌的机制研究，2021/1-2024/12，58万，在研，参加
近期论文
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1. Mingtian Deng, Baobao Chen, Yingnan Yang, Yongjie Wan, Zifei Liu, Jun Fu, Feng Wang*, Characterization of transcriptional activity during ZGA in mammalian SCNT embryo. Biology of reproduction, 2021, ioab127 (IF=4.285)
2. Mingtian Deng#, Yongjie Wan#, Zifei Liu, Cai Yu, Baobao Chen, Yanli Zhang*, Feng Wang*, Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b, Molecular Therapy-Nucleic Acids, 2021,24:54-66（IF=8.886, top10）
3. Yu Cai#, Mingtian Deng#, Qifan Zhang, Zifei Liu, Liang Wang, Wenwen Sheng, Yanli Zhang, Peihua You, Ziyu Wang*, Feng Wang*. Effects of dietary betaine supplementation on biochemical parameters of blood and testicular oxidative stress in Hu sheep. Theriogenology, 2021, 164: 65-73（IF=2.740, top20）
4. Mingtian Deng, Baobao Chen, Yongjie Wan, Zifei Liu, Yu Cai, Guoming Zhang, Yixuan Fan, Yanli Zhang* and Feng Wang*, YTHDF2 Regulates Maternal Transcriptome Degradation and Embryo Development in Goat. Frontiers in Cell and Developmental Biology, 2020, 8: 1040-1050（IF=6.684, top20）
5. Mingtian Deng, Baobao Chen, Zifei Liu, Yongjie Wan, Hua Yang, Yu Cai, Jianguo Zhou, Yanli Zhang, Feng Wang*. Aberrant DNA and histone methylation during zygotic genome activation in goat cloned embryos. Theriogenology, 2020, 148: 27-36（IF=2.740，top20）
6. Mingtian Deng, Guomin Zhang, Yu Cai, Zifei Liu, Yanli Zhang, Fanxing Meng, Feng Wang, Yongjie Wan*, DNA methylation dynamics during zygotic genome activation in goat. Theriogenology, 2020, 156: 144-154（IF=2.740，top20）
7. Mingtian Deng, Zifei Liu, BaoBao Chen, Yu Cai, Yongjie Wan*, Feng Wang*. Locus-Specific Regulation of Xist Expression Using the CRISPR-Cas9-Based System. DNA Cell Biol, 2020, 39(4): 572-578（IF=3.311）
8. Mingtian Deng, Baobao Chen, Zifei Liu, Yu Cai, Yongjie Wan, Jianguo Zhou, Feng Wang*. Exchanges of histone methylation and variants during mouse zygotic genome activation. Zygote, 2020, 28(1): 51-58
9. 邓明田, 王锋 (2020). 哺乳动物合子基因组激活调控的研究进展. 黑龙江动物繁殖 28: 37-41.
10. Mingtian Deng, Zifei Liu, Caifang Ren, Shiyu An, Yongjie Wan*, Feng Wang*. Highly methylated Xist in SCNT embryos was retained in deceased cloned female goats. Reproduction, Fertility and Development, 2019, 31(5): 855-866
11. Mingtian Deng, Zifei Liu, Caifang Ren, Guomin Zhang, Jing Pang, Yanli Zhang, Feng Wang*, Yongjie Wan*. Long noncoding RNAs exchange during zygotic genome activation in goat. Biology of reproduction, 2018, 99(4): 707-717（IF= 4.285）
12. Mingtian Deng, Caifang Ren, Zifei Liu, Guomin Zhang, Feng Wang*, Yongjie Wan*. Epigenetic status of H19-Igf2 imprinted genes and loss of 5-hydroxymethylcytosine in the brain of cloned goats. Cellular reprogramming, 2017, 19(3): 199-207
13. Yongjie Wan#, Mingtian Deng#, Guomin Zhang, Caifang Ren, Hao Zhang, Yanli Zhang, Lizhong Wang, Feng Wang*. Abnormal expression of DNA methyltransferases and genomic imprinting in cloned goat fibroblasts. Cell biology international, 2016, 40(1): 74-82
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