个人简介

教育与工作经历 2010年南京农业大学博士毕业留校任教至今，曾在美国加州大学戴维斯分校访学。 奖励及荣誉 南京农业大学钟山学术新秀，作为主要参加人获省部级科研二等奖1项（2017），学校出国留学人员考核优秀（2017）；学校教学质量优秀奖（2016）；江苏省教学成果二等奖(2013，3/10);南京农业大学教学成果奖一等奖（2020,2/7）；南京农业大学教学成果奖特等奖（2020,3/5）；多次学校获教学质量综合评价优秀。参与讲授的《动物繁殖学》课程分别获首批国家级一流本科课程（2020），江苏省精品在线开放课程（2017），首批精品资源共享课程（2016），及精品资源共享课程（2013）。 承担科研项目 先后主持国家自然科学基金面上项目2项、江苏现代农业（肉羊）产业技术体系岗位专家项目、 国家重点研发计划项目课题子任务、江苏省自然科学基金面上项目、国家自然科学基金青年项目、 中央高校基本科研业务费自主创新重点项目等。 作为项目骨干参与团队承担的国家肉羊产业技术体系岗位科学家项目、江苏省重点研发计划项目、江苏省农业重大新品种创制计划项目等。

研究领域

动物胚胎工程；肉羊遗传育种与繁殖调控

动物遗传育种与繁殖

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

围绕肉羊繁殖性状调控机理和繁殖新技术领域已发表学术论文70余篇，其中第一或通讯作者发表SCI论文30余篇，中文核心期刊论文10余篇。主编参编教材著作8部。近五年主要代表性论文如下： 1. Mingtian Deng #, Yongjie Wan#, Zifei Liu1, Cai Yu1, Baobao Chen, Yanli Zhang*, Feng Wang*, Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b，Molecular Therapy-Nucleic Acids,2021,24:54-66. 2. Yang H, Ma J, Wan Z, Wang Q, Wang Z, Zhao J, Wang F, Zhang Y*. Characterization of sheep spermatogenesis through single-cell RNA sequencing. FASEB J, 2021, 35(2):e21187. 3. Pang J , Yang H , Feng X , Wang Q, Cai Y, Liu Z, Wang C, Wang F, Zhang Y*. HT-2 toxin affects cell viability of goat spermatogonial stem cells through AMPK-ULK1 autophagy pathways. Theriogenology, 2021, 164. 4. Mingtian Deng, Baobao Chen, Zifei Liu, Yu Cai, Yongjie Wan, Guomin Zhang, Yixuan Fan, Yanli Zhang*, Feng Wang*. YTHDF2 Regulates Maternal Transcriptome Degradation and Embryo Development in Goat. Frontiers in Cell and Developmental Biology, 2020,29:580367. 5. Jie Zhao, Hua Yang, Mingtian Deng, Jianyu Ma, Zhibo Wang, Fanxing Meng, Feng Wang, Yan-Li Zhang*. Expression Pattern and Potential Role of Nanos3 in Regulating Testosterone Biosynthesis in Leydig Cells of Sheep. Theriogenology 2020 May 16;154:31-42. 6. Yang H, Ma J, Wang Z, Yao X, Zhao J, Zhao X, Wang F, Zhang Y*. Genome-wide analysis and function prediction of long noncoding RNAs in sheep pituitary gland associated with sexual maturation. Genes. 2020;11(3):320. 7. Zheng J, Wang Z, Yang H, Yao X, Yang P, Ren C, Wang F, Zhang Y*. Pituitary transcriptomic study reveals the differential regulation of lncRNAs and mRNAs related to prolificacy in different FecB genotyping sheep. Genes(Basel). 2019;10(2):1-17. 8. Jie Zhao ,Feng-zhe Li, Jie Wu , Hua Yang, Jian Zheng, Jing Pang, Fan-xing Meng , Feng Wang, Yan-li Zhang*.Effect of CREB1 promoter non-CpG island methylation on its differential expression profile on sheep ovaries associated with prolificacy. Tissue and cell, 2019;58:61‐69. 9. Zhang Y, Li P, Han L, Pang J, Yang H, Guo R, Wang F*. Induction of goat bone marrow mesenchymal stem cells into putative male germ cells using mRNA for STRA8, BOULE and DAZL. Cytotechnology. 2019;71(2):563-572. 10. Yang H, Wang F, Li F, Ren C, Pang J, Wan Y, Wang Z, Feng X, Zhang Y*. Comprehensive analysis of long noncoding RNA and mRNA expression patterns in sheep testicular maturation. Biololgy of Reproduction. 2018;99(3):650-661. 11. Feng X, Li F, Wang F, Zhang G, Pang J, Ren C, Zhang T, Yang H, Wang Z, Zhang Y*. Genome-wide differential expression profiling of mRNAs and lncRNAs associated with prolificacy in Hu sheep. Biosci Rep. 2018;38(2):157. 12. Zhang YL, Zhang GM, Jia RX, Wan YJ, Yang H, Sun LW, Han L, Wang F. Non-invasive assessment of culture media from goat cloned embryos associated with subjective morphology by gas chromatography - mass spectroscopy-based metabolomic analysis. Anim Sci J. 2018 Jan;89(1):31-41. 13. Zhang Y, Sastre D, Wang F. CRISPR/cas9 genome editing: a promising tool for therapeutic applications of induced pluripotent stem cells. Curr Stem Cell Res Ther. 2018;13(4):243-251. 14. Zhang Y, Yang H, Han L, Li F, Zhang T, Pang J, Feng X, Ren C, Mao S, Wang F*. Long noncoding RNA expression profile changes associated with dietary energy in the sheep testis during sexual maturation. Sci Rep. 2017;7(1):5180. 15. Zhang Y, Li F, Feng X, Yang H, Zhu A, Pang J, Han L, Zhang T, Yao X, Wang F*. Genome-wide analysis of DNA methylation profiles on sheep ovaries associated with prolificacy using whole-genome bisulfite sequencing. BMC Genomics. 2017;18(1):759. 16. Zhang G, Deng M, Lei Z, Wan Y, Nie H, Wang Z, Fan Y, Wang F, Zhang Y*. Effects of NRF1 on steroidogenesis and apoptosis in goat luteinized granulosa cells. Reproduction. 2017;154(2):111-122. 17. Yao X, Zhang G, Guo Y, Samahy M, Liu Z, Wang F, Zhang Y*. Vitamin D receptor expression and potential role of vitamin D on cell proliferation and steroidogenesis in goat ovarian granulosa cells. Theriogenology, 2017,102:162-173. 18. Ren C, Deng M, Fan Y, Yang H, Wang D, Wang F, Zhang Y*. Genome-wide analysis reveals lncRNAs as novel regulators of myofiber growth in Hu sheep. Genes. 2017;8(8):191. 19. Pang J, Li F, Feng X, Yang H, Han L, Fan Y, Nie H, Wang Z, Wang F, Zhang Y*. Influences of different dietary energy level on sheep testicular development associated with AMPK/ULK1/autophagy pathway. Theriogenology. 2018;108:362-370. 20. Fan Y, Wang Z, Ren C, Ma T, Deng K, Feng X, Li F, Wang F, Zhang Y*. Effect of dietary energy restriction and subsequent compensatory feeding on testicular transcriptome in developing rams. Theriogenology. 2018;119:198-207. 21. ZHANG Hao, SUN Ling-wei, WANG Zi-yu, MA Tie-wei, DENG Ming-tian, WANG feng, ZHANG Yan-li*. Energy and protein requirements for maintenance of Hu sheep during pregnancy. Journal of Integrative Agriculture, 2018, 17 (1) :173-183 22. Li PZ, Yan GY, Han L, Pang J, Zhong BS, Zhang GM, Wang F, Zhang YL*. Overexpression of STRA8, BOULE, and DAZL Genes Promotes Goat Bone Marrow-Derived Mesenchymal Stem Cells In Vitro Transdifferentiation Toward Putative Male Germ Cells. Reprod Sci. 2017 Feb;24(2):300-312. 23. Jia R, Zhang G, Fan Y, Zhou Z, Wan Y, Zhang Y*, Wang Z, Wang F.MBD1 and MeCP2 expression in embryos and placentas from transgenic cloned goats. Zygote. 2017 Aug;25(4):462-471. 24. Zhang Y, Han L, Yang H, Pang J, Li P, Zhang G, Li F, Wang F*. Bisphenol A affects cell viability involved in autophagy and apoptosis in goat testis sertoli cell. Environ Toxicol Pharmacol. 2017;55:137-147. 25. Guo R, Wan Y, Xu D, Cui L, Deng M, Zhang G, Jia R, Zhou W, Wang Z, Deng K, Huang M, Wang F*, Zhang Y*. Generation and evaluation of myostatin knock-out rabbits and goats using CRISPR/Cas9 system. Sci Rep. 2016;6:29855. 26. 周文君，郭日红，邓明田，王锋，张艳丽*. RS-1提高CRISPR-Cas9系统介导的hLF基因敲入效率.生物工程学报. 2017;8:1224-1234. 27. 颜光耀, 李佩真,任才芳, 王锋, 张艳丽*.山羊生殖细胞特异报告载体pVASA-EGFP的构建及表达.生物工程学报. 2015 , 31 (9) :1313-1324 28. 杨花,赵欣月,万珍,王锋,张艳丽*.HSD17B12基因对湖羊垂体细胞促性腺激素合成的影响.畜牧兽医学报,2021,52(03):703-713. 29. 汪棋,汪长建,魏宗友,陆汉希,姚晓磊,杨花,王锋,张艳丽*.AMPK激活剂在绵羊精液冷冻保存中的作用研究.畜牧兽医学报,2020,51(12):3033-3045. 参编的著作 1. 主编《动物繁殖学实验教程》（第2版），中国农业大学出版社，2017 2. 副主编《羊业科学研究进展(2015)》，中国农业科学技术出版社，2015 3. 副主编《肉用山羊养殖与疫病防治新技术》，中国农业科学技术出版社，2015 4. 参编《肉羊饲养实用技术》，中国农业科学技术出版社，2015 5. 参编《肉羊标准化高效养殖关键技术》，江苏凤凰科学技术出版社，2016 6. 参编《肉羊饲养新技术》，中国农业科学技术出版社，2014 7. 参编“十二五”规划教材《动物繁殖学》，中国农业大学出版社，2012.05，北京，978-7-5655-0468-6 8. 参编《百名专家谈转基因》，中国农业出版社，2011.09

学术兼职

中国畜牧兽医学会动物繁殖学分会理事；全国草食动物健康生产科技创新联盟常务理事；Animal Reproduction Science期刊编委