Hong, Guosong - Stanford University - Department of Materials Science and Engineering

个人简介

Dr. Guosong Hong received his PhD in chemistry from Stanford University in 2014, and then carried out postdoctoral studies at Harvard University. Dr. Hong joined Stanford Materials Science and Engineering and Neurosciences Institute as an assistant professor in 2018. He is a recipient of the NIH Pathway to Independence (K99/R00) Award, the MIT Technology Review ‘35 Innovators Under 35’ Award, the Science PINS Prize for Neuromodulation, the NSF CAREER Award, the Walter J. Gores Award for Excellence in Teaching, and the Rita Allen Foundation Scholars Award. Education Postdoc training, Harvard University, Chemistry and Chemical Biology (2018) PhD, Stanford University, Chemistry (2014)

研究领域

Guosong Hong's research aims to bridge materials science and neuroscience, and blur the distinction between the living and non-living worlds by developing novel neuroengineering tools to interrogate and manipulate the brain. Specifically, the Hong lab is currently developing ultrasound, infrared, and radiofrequency-based in-vivo neural interfaces with minimal invasiveness, high spatiotemporal resolution, and cell-type specificity.

近期论文

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Force-Based Neuromodulation. Accounts of chemical research Cooper, L., Malinao, M. G., Hong, G. 2024 DOI 10.1021/acs.accounts.4c00074 Mechanoluminescent Light Sources Based on Nanostructured Systems for Biomedical Applications: A Review ACS APPLIED NANO MATERIALS Yang, M., Ge, X., Zheng, L., Huang, Y., Zhong, J., Tu, D., Hong, G., Yang, F. 2024 DOI 10.1021/acsanm.4c00675 Near-infrared II fluorescence imaging NATURE REVIEWS METHODS PRIMERS Schmidt, E., Ou, Z., Ximendes, E., Cui, H., Keck, C. C., Jaque, D., Hong, G. 2024; 4 (1) DOI 10.1038/s43586-024-00301-x Mechanoluminescence and Mechanical Quenching of Afterglow Luminescent Particles for Wearable Photonic Display ADVANCED FUNCTIONAL MATERIALS Kim, S., Yang, F., Jung, H., Hong, G., Hahn, S. 2024 DOI 10.1002/adfm.202314861 Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo. Nature protocols Jiang, S., Wu, X., Yang, F., Rommelfanger, N. J., Hong, G.2023 DOI 10.1038/s41596-023-00895-8 A Nanozyme-Based Electrode for High-Performance Neural Recording. Advanced materials (Deerfield Beach, Fla.)Liu, S., Wang, Y., Zhao, Y., Liu, L., Sun, S., Zhang, S., Liu, H., Liu, S., Li, Y., Yang, F., Jiao, M., Sun, X., Zhang, Y., Liu, R., Mu, X., Wang, H., Zhang, S., Yang, J., Xie, X., Duan, X., Zhang, J., Hong, G., Zhang, X., Ming, D. 2023: e2304297 DOI 10.1002/adma.202304297 Wireless deep-brain neuromodulation using photovoltaics in the second near-infrared spectrum. Device Cui, H., Zhao, S., Hong, G.2023; 1 (4) DOI 10.1016/j.device.2023.100113 Laminin-coated electronic scaffolds with vascular topography for tracking and promoting the migration of brain cells after injury. Nature biomedical engineering Yang, X., Qi, Y., Wang, C., Zwang, T. J., Rommelfanger, N. J., Hong, G., Lieber, C. M.2023 DOI 10.1038/s41551-023-01101-6 Bioinspired nanotransducers for neuromodulation NANO RESEARCH Yang, F., Wu, X., Cai, S., Hong, G.2023 DOI 10.1007/s12274-023-6136-6 Direct-print three-dimensional electrodes for large- scale, high-density, and customizable neural inter- faces. bioRxiv : the preprint server for biology Wang, P., Wu, E. G., Uluşan, H., Phillips, A. J., Rose Hays, M., Kling, A., Zhao, E. T., Madugula, S., Vilkhu, R. S., Vasireddy, P. K., Hier-Lemann, A., Hong, G., Chichilnisky, E. J., Melosh, N. A.2023 DOI 10.1101/2023.05.30.542925 Nanotransducer-Enabled Deep-Brain Neuromodulation with NIR-II Light. ACS nano Wu, X., Yang, F., Cai, S., Pu, K., Hong, G.2023 DOI 10.1021/acsnano.2c12068 An optimized bioluminescent substrate for non-invasive imaging in the brain. Nature chemical biology Su, Y., Walker, J. R., Hall, M. P., Klein, M. A., Wu, X., Encell, L. P., Casey, K. M., Liu, L. X., Hong, G., Lin, M. Z., Kirkland, T. A.2023 DOI 10.1038/s41589-023-01265-x Advanced Light Delivery Materials and Systems for Photomedicines. Advanced drug delivery reviews Kim, S., Lee, G., Hong, G., Hyun Yun, S., Kwang Hahn, S.2023: 114729 DOI 10.1016/j.addr.2023.114729 Principles and applications of sono-optogenetics. Advanced drug delivery reviews Yang, F., Kim, S. J., Wu, X., Cui, H., Kwang Hahn, S., Hong, G.2023: DOI 10.1016/j.addr.2023.114711 Ultrasound-activated luminescence with color tunability enabled by mechanoluminescent colloids and perovskite quantum dots. Nanoscale Yang, F., Cui, H., Wu, X., Kim, S., Hong, G.2023 DOI 10.1039/d2nr06129e Ultrasound-Triggered In Situ Photon Emission for Noninvasive Optogenetics. Journal of the American Chemical Society Wang, W., Wu, X., Kevin Tang, K. W., Pyatnitskiy, I., Taniguchi, R., Lin, P., Zhou, R., Capocyan, S. L., Hong, G., Wang, H.2023 DOI 10.1021/jacs.2c10666 Protocol for wireless deep brain stimulation in freely behaving mice with infrared light. STAR protocols Wu, X., Hong, G.2022 DOI 10.1016/j.xpro.2022.101757 Controlled afterglow luminescent particles for photochemical tissue bonding. Light, science & applications Kim, S., Choi, M., Hong, G., Hahn, S. K.2022; DOI 10.1038/s41377-022-01011-3 Palette of Rechargeable Mechanoluminescent Fluids Produced by a Biomineral-Inspired Suppressed Dissolution Approach. Journal of the American Chemical Society Yang, F., Wu, X., Cui, H., Jiang, S., Ou, Z., Cai, S., Hong, G.2022 DOI 10.1021/jacs.2c06724 Shedding light on neurons: optical approaches for neuromodulation. National science review Jiang, S., Wu, X., Rommelfanger, N. J., Ou, Z., Hong, G.2022; DOI 10.1093/nsr/nwac007 A biomineral-inspired approach of synthesizing colloidal persistent phosphors as a multicolor, intravital light source. Science advances Yang, F., Wu, X., Cui, H., Ou, Z., Jiang, S., Cai, S., Zhou, Q., Wong, B. G., Huang, H., Hong, G.2022; DOI 10.1126/sciadv.abo6743 Cooling the pain. Science (New York, N.Y.)Jiang, S., Hong, G.2022 DOI 10.1126/science.abm8159 Scalable Three-Dimensional Recording Electrodes for Probing Biological Tissues. Nano letters Lee, J. M., Lin, D., Hong, G., Kim, K., Park, H., Lieber, C. M.2022 DOI 10.1021/acs.nanolett.2c01444 Pristine carbon nanotubes are efficient absorbers at radio frequencies. Nanotechnology Rommelfanger, N. J., Brinson, K., Bailey, J. E., Bancroft, A. M., Ou, Z., Hong, G.2022 DOI 10.1088/1361-6528/ac6cf8 Shedding light on neurons: optical approaches for neuromodulation NATIONAL SCIENCE REVIEW Jiang, S., Wu, X., Rommelfanger, N. J., Ou, Z., Hong, G.2022 DOI 10.1093/nsr/nwac007 Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window. Nature biomedical engineering Wu, X., Jiang, Y., Rommelfanger, N. J., Yang, F., Zhou, Q., Yin, R., Liu, J., Cai, S., Ren, W., Shin, A., Ong, K. S., Pu, K., Hong, G.2022 DOI 10.1038/s41551-022-00862-w Sub-10-nm graphene nanoribbons with atomically smooth edges from squashed carbon nanotubes NATURE ELECTRONICS Chen, C., Lin, Y., Zhou, W., Gong, M., He, Z., Shi, F., Li, X., Wu, J., Lam, K., Wang, J., Yang, F., Zeng, Q., Guo, J., Gao, W., Zuo, J., Liu, J., Hong, G., Antaris, A. L., Lin, M., Mao, W. L., Dai, H.2021 DOI 10.1038/s41928-021-00633-6 Learning from the brain's architecture: bioinspired strategies towards implantable neural interfaces. Current opinion in biotechnology Rommelfanger, N. J., Keck, C. H., Chen, Y., Hong, G.2021 DOI 10.1016/j.copbio.2021.07.020 On the feasibility of wireless radio frequency ablation using nanowire antennas APL MATERIALS Rommelfanger, N. J., Hong, G.2021 DOI 10.1063/5.0053189 Nanotransducers for Wireless Neuromodulation. Matter Li, X., Xiong, H., Rommelfanger, N., Xu, X., Youn, J., Slesinger, P. A., Hong, G., Qin, Z.2021; DOI 10.1016/j.matt.2021.02.012 Differential Heating of Metal Nanostructures at Radio Frequencies PHYSICAL REVIEW APPLIED Rommelfanger, N. J., Ou, Z., Keck, C. C., Hong, G.2021; 15 (5) DOI 10.1103/PhysRevApplied.15.054007 Differential heating of metal nanostructures at radio frequencies. Physical review applied Rommelfanger, N. J., Ou, Z., Keck, C. H., Hong, G.2021; DOI 10.1103/physrevapplied.15.054007 All-Tissue-like Multifunctional Optoelectronic Mesh for Deep-Brain Modulation and Mapping. Nano letters Lee, J. M., Lin, D., Kim, H., Pyo, Y., Hong, G., Lieber, C. M., Park, H.2021 DOI 10.1021/acs.nanolett.1c00425 How is flexible electronics advancing neuroscience research? Biomaterials Chen, Y., Rommelfanger, N. J., Mahdi, A. I., Wu, X., Keene, S. T., Obaid, A., Salleo, A., Wang, H., Hong, G.2020; DOI 10.1016/j.biomaterials.2020.120559 An "All-in-One" Catheter: Surgery of the Future MATTER Chen, Y., Yin, R., Hong, G.2020; 3 (6): 1829–31 DOI 10.1016/j.matt.2020.11.005 Conjugated Polymers Enable a Liquid Retinal Prosthesis TRENDS IN CHEMISTRY Rommelfanger, N. J., Hong, G.2020; 2 (11): 961–64 DOI 10.1016/j.trechm.2020.08.004 Conjugated Polymers Enable a Liquid Retinal Prosthesis. Trends in chemistry Rommelfanger, N. J., Hong, G.2020; 2 (11): 961-964 DOI 10.1016/j.trechm.2020.08.004 Bioinspired Materials for In Vivo Bioelectronic Neural Interfaces. Matter Woods, G. A., Rommelfanger, N. J., Hong, G.2020; DOI 10.1016/j.matt.2020.08.002 Seeing the sound. Science (New York, N.Y.)Hong, G. n.2020; 369 (6504): 638