Brujic, Jasna - New York University - Center for Soft Matter Research

个人简介

Jasna Brujic is an associate Professor of Physics in the Physics Department of New York University. She is one of several core faculty members that compose the Center for Soft Matter Research. Professor Brujic received her Ph.D. for work on the transmission of stress through particulate matter at the Cavendish Laboratory of Cambridge University. She then conducted post-doctoral research on the dynamics of single molecule protein systems in the lab of Julio Fernandez in the Biology Department of Columbia University, New York City. Employment History 2013- Associate Professor at New York University (with tenure) 2007- 2013 Assistant Professor at New York University, Center for Soft Matter Research (CSMR), Physics Department, U. S. A. 2004 – 2007 Post-Doctoral Researcher, Columbia University, Biology Department, U.S.A. Visiting Positions Summer Visiting Chair Joliot, Ecole Supérieure de Physique et de Chimie 2017 Industrielles (ESPCI), Paris, France 2013-2014 Sabbatical Visiting Fellow, University of Cambridge, U.K. Fall 2010 Goddard Fellow, Mechanobiology Institute, National University of Singapore Education 2000 – 2004 Ph.D. Degree, University of Cambridge, Gonville and Caius College, Cavendish Laboratory, Department of Physics, U.K. (Adviser: Sam F. Edwards) 1996 - 2000 MSci (Hons) Chemistry with a Year Abroad (France), Imperial College of Science, Technology & Medicine, London Degree Result: 1st Class Honours 1999 - 2000 Final Year at the ESPCI, Paris, France (Adviser: Francois Lequeux) Awards / Grants 2008 – 2019 Materials Research Science and Engineering Center (MRSEC) for Semantophoretic Assemblies at NYU: IRG1 co-Leader 2008 – 2009 Whitehead Fellowship for Junior Faculty in Biomedical and Biological Sciences, Protein Folding at the Single Molecule Level 2006 – 2011 Burroughs Wellcome Fellowship:Career Award at the Scientific Interface, Mechanical Networks in Biology: Proteins to Cells 2009 – 2010 NYU-Poly Seed Grants, Effect of Fluorination on Protein Stability 2010 – 2015 Career Award from the National Science Foundation, Microstructure of Jammed Particulate Matter 2015 Iakobachvili Faculty Science Award Folding of Emulsion Polymers 2016 – 2017 University Research Challenge Fund, Emulsions as a Novel Platform for Bacterial Population Dynamics and Emergence of Antibiotic Resistance 2016 – 2018 Scialog Fellow: Moore Foundation/Research Corporation 2017 – 2020 National Science Foundation, DMR Award, Self-Assembly and Controlled Folding of Emulsion Polymers

研究领域

JAMMING A confocal image of the packing of silicone oil droplets in an emulsion. A “stack” of such images can be analyzed by a software package to determine various characteristics of the packing, e.g. distribution of nearest neighbors. PROTEIN FOLDING An abstract representation of a protein’s free energy landscape. Statistical analysis of protein unfolding times can yield information about the form of the molecule’s underlying energy surface. BIOMIMETICS Characterizing the mechanical properties and dynamics of tissues has been of growing interest in the last 10 years with the motivation to understand phenomena such as embryogenesis or morphogenetic movements. In vivo studies are difficult to perform and interpret due to the many interactions that are at stake in a cellular assembly. A biomimetic approach can thus be used to design and characterize simplified systems that mimic tissues in vitro. AFM DEVELOPMENT Work is being done to improve acquisition speed and control. This will allow rheology and torque experiments to be performed on single molecule systems.

近期论文

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Tunable Persistent Random Walk in Swimming Droplets Physical Review X (May 14th, 2020) Adrien Izzet, Pepijn G. Moerman, Preston Gross, Jan Groenewold, Andrew D. Hollingsworth, Jérôme Bibette, and Jasna Brujic Assembly and Dynamic Analysis of Square Colloidal Crystals via Templated Capillary Assembly Langmuir (September 9, 2019) Cicely Shillingford, Veronica Grebe, Angus McMullen, Jasna Brujic* and Marcus Weck* Freely jointed polymers made of droplets Phys. Rev. Lett. (September 26th, 2018), in “Editor’s Suggestion” and “Featured in Physics”. Angus McMullen, Miranda Holmes-Cerfon, Francesco Sciortino, Alexander Y. Grosberg, and Jasna Brujic Multivalent, multiflavored droplets by design PNAS. (August 27th, 2018) Yin Zhang, Xiaojin He, Rebecca Zhuo, Ruojie Sha, Jasna Brujic, Nadrian C. Seeman, and Paul M. Chaikin Emulsion patterns in the wake of a liquid–liquid phase separation front PNAS (March 21st, 2018) P. G. Moerman, P. C. Hohenberg, E. Vanden-Eijnden and J. Brujic Solute-mediated interactions between active droplets Phys. Rev. E 96, 032607 (2017) P. G. Moerman, H. W. Moyses, E. B. van der Wee, D. G. Grier, A. van Blaaderen, W. K. Kegel, J. Groenewold, and J. Brujic Sequential self-assembly of DNA functionalized droplets Nature Communications, 8, 21 (2017) Y. Zhang, L. L. Pontani, X. He, R. Sha, N. C. Seeman, J. Brujic, P. M. Chaikin Evidence for Marginal Stability in Emulsions Phys. Rev. Lett. 117, 208001 (2016) J. Lin, I. Jordjadze, L.-L. Pontani, M. Wyart, J. Brujic Kinetic control of the coverage of oil droplets by DNA-functionalized colloids Sci. Adv., 2, 8 (2016) D. Joshi, D. Bargteil, A. Caciagli, J. Burelbach, Z. Xing, A. Nunes, D. Pinto, N. Araujo, J. Brujic, E. Eiser Cis and Trans Cooperativity of E-Cadherin Mediates Adhesion in Biomimetic Lipid Droplets Biophys. J., 110, 2, 391-399 (2016) L.-L. Pontani, I. Jorjadze, J. Brujic Local structure controls the nonaffine shear and bulk moduli of disordered solids Scientific Reports, 6, 18724 (2016) M. Schlegel, J. Brujic, E. M. Terentjev, A. Zaccone Multiphase Protein Microgels Macromol. Biosci., 15, 501-508 (2015) U. Shimanovich, Y. Song, J. Brujic, H.C. Shum, T.P.J. Knowles Tailoring of High-Order Multiple Emulsions by the Liquid-Liquid Phase Separation of Ternary Mixtures Angew. Chem. Int. Ed., 53, 44, 11793-11797 (2014) M. Haase and J. Brujic Self-Assembly of Polysaccharides Gives Rise to Distinct Mechanical Signatures in Marine Gels Biophys. J., 107, 2, 355 – 364 (2014) G. Pletikapic, H. Lannon, U. Murvai, M.S. Kellermayer, V. Svetlicic, J. Brujic Specificity, flexibility and valence of DNA bonds guide emulsion architecture Soft Matter, 9, 9816-9823 (2013) L. Feng*, L.L. Pontani*, R. Dreyfus, P. Chaikin, J. Brujic Immiscible 1 lipids control the morphology of patchy emulsions Soft Matter, 9, 7150-7157 (2013) L.L. Pontani, M.F. Haase, I. Raczkowska, J. Brujic Domain-domain interactions in Filamin A (16-23) impose a hierarchy of unfolding forces Biophys. J., 104, 9, 2022 – 2230 (2013) T. Xu, H. Lannon, S. Wolf, F. Nakamura, J. Brujic Force-clamp experiments reveal the free-energy profile and diffusion coefficient of the collapse of protein molecules PRL, 110, 12, 128301 – 128305 (2013) H. Lannon, J.S. Haghpanah, J.K. Montclare, E. Vanden-Eijnden, J. Brujic Microscopic approach to the nonlinear elasticity of compressed emulsions PRL, 110, 4, 048302 – 048306 (2013) I. Jorjadze, L.L. Pontani, J. Brujic