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个人简介

教育背景 2013-2016 中国科学院上海应用物理研究所 博士 2010-2013 中国科学院上海应用物理研究所 硕士 2006-2010 合肥工业大学 学士 工作经历 2021.08-至今 上海交通大学化学化工学院,长聘教轨副教授 2018.10-2021.07,上海交通大学化学化工学院,长聘教轨助理教授 2016.9-2018.9,华南理工大学发光材料与器件国家重点实验室,博士后

研究领域

1、原子精细发光团簇制备及应用 2、生物分析化学 3、细胞膜成像分析

近期论文

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Chengpin Liang, Qiuling Huang, Haoran Zheng, Mulin Duan, Xinyi Cheng, Jielin Chen, Qian Li, Zhiyun Zhang*, Chunhai Fan, He Tian, Jianlei Shen*.Probing Cell Membrane Tension Using DNA Framework-Encoded Vibration-Induced Emission Molecular Assemblies.J. Am. Chem. Soc. 2024, Accepted. Cong Li,#, Xiaodong Xie,#, Mingqiang Li, Haozhi Wang, Xinyi Cheng, Jichao Zhang, Qian Li, Jiang Li, Xiaolei Zuo, Chunhai Fan*, J. Shen*. JACS. 2024. In press. H. Zheng, Y. Zhou, B. Yan, G. Zhou, X. Cheng, S. Lin, M. Duan, J. Li, L. Wang, C. Fan, J. Chen*, and J. Shen*. DNA Framework-Guided Self-Limiting Aggregation for Highly Luminescent Metal Cluster Nanoaggregates. JACS. 2024. DOI: 10.1021/jacs.4c02401 C. Li, J. Chen, T. Man, B. Chen, J. Li, Q. Li, X. Yang, Y. Wan*, C. Fan, J. Shen*.; DNA framework-engineered assembly of cyanine dyes for structural identification of nucleic acids. JACS Au. 2024. DOI: 10.1021/jacsau.3c00826. Chen J#, Gu P#, Ran G#, Zhang Y#, Li M, Chen B, Lu H, Han Y, Zhang W, Tang Z, Yan Q, Sun R, Fu X, Chen G, Shi Z, Wang S, Liu X, Li J, Wang L,Zhu Y*, Shen J*, Tang B. Z.*, Fan C.*. Atomically precise photothermal nanomachines. Nature Materials. 2023,https://doi.org/10.1038/s41563-023-01721-y. Li, Y.#; Zheng, H.#; Lu, H.#; Duan, M.; Li, C.; Li, M.; Li, J.; Wang, L.; Li, Q.; Chen, J.*; Shen, J.*; Noncanonical Condensation of Nucleic Acid Chains by Hydrophobic Gold Nanocrystals. JACS Au. 2023. 3, 8, 2206–2215. Zheng, H.#; Li, H.#; Li, M.#; Zhai, T.; Xie, X.; Li, C.; Jing, X.; Liang, C.; Li, Q.; Zuo, X.; Li, J.; Fan, J.*; Shen, J.*; Peng, X.; Fan C.; A Membrane Tension-Responsive Mechanosensitive DNA Nanomachine. Angewandte Chemie-International Edition 2023. 62, e202305896. Zhai, T.#; Zheng, H.#; Fang, W.#; Gao, Z.; Song, S.; Zuo, X.; Li, Q.; Wang, L.; Li, J.; Shi, J.; Liu, X.; Tian, Y.; Shen, J.*; Fan, C., DNA-Encoded Gold-Gold Wettability for Programmable Plasmonic Engineering. Angewandte Chemie-International Edition 2022. Doi: 10.1002/anie.202210377. Liang, C.; Chen, J.; Li, M.; Ge, Z.; Fan, C.*; Shen, J.*, Probing the self-assembly process of amphiphilic tetrahedral DNA frameworks. Chemical Communications 2022, 58 (60), 8352-8355. Liang, C.; Chen, J.; Li, M.; Li, Q.; Fan, C.*; Luo, S.*; Shen, J.*, Programming the self-assembly of amphiphilic DNA frameworks for sequential boolean logic functions. Chemical Communications 2022, 58 (63), 8786-8789. Li, Y.; Zhai, T.; Chen, J.; Shi, J.; Wang, L.; Shen, J.*; Liu, X.*, Water-Dispersible Gold Nanoclusters: Synthesis Strategies, Optical Properties, and Biological Applications. Chemistry-a European Journal 2022, 28 (10). Li, Y.; Lu, H.; Qu, Z.; Li, M.; Zheng, H.; Gu, P.; Shi, J.; Li, J.; Li, Q.; Wang, L.; Chen, J.; Fan, C.; Shen, J.*, Phase transferring luminescent gold nanoclusters via single-stranded DNA. Science China-Chemistry 2022, 65 (6), 1212-1220. Zhai, T.; Sun, C.; Ye, D.; Xia, K.; Liu, X.; Fan, C.; Li, Q.*; Shen, J.*, Electrochemically driven assembly of framework nucleic acids. Journal of Electroanalytical Chemistry 2022, 905. Feng, L.; Li, C.; Wang, L.; Li, J.; Liu, X.; Li, Q.; Luo, S.*; Shen, J.*, Self-Referenced Surface-Enhanced Raman Scattering Nanosubstrate for the Quantitative Detection of Neurotransmitters. ACS Applied Bio Materials 2022, 5 (5), 2403-2410. Shen, J.; Situ, B.; Du, X.; Wang, Z.; Hu, R.; Li, B.; Qin, A.; Tang, B. Z., Aggregation-Induced Emission Luminogen-Based Dual-Mode Enzyme-Linked Immunosorbent Assay for Ultrasensitive Detection of Cancer Biomarkers in a Broad Concentration Range. ACS Sensors 2022, 7 (3), 766-774. Chen, B.; Huang, Q.; Qu, Z.; Li, C.; Li, Q.; Shi, J.; Fan, C.; Wang, L.; Zuo, X.; Shen, J.*; Li, J.*, Probing Transient DNA Conformation Changes with an Intercalative Fluorescent Excimer. Angewandte Chemie-International Edition 2021, 60 (12), 6624-6630. Feng, L.; Li, J.; Sun, J.; Wang, L.; Fan, C.; Shen, J.*, Recent Advances of DNA Nanostructure-Based Cell Membrane Engineering. Advanced Healthcare Materials 2021, 10 (6). Gu, P.; Chen, B.; Zhai, T.; Li, Q.; Zuo, X.; Wang, L.; Qin, A.; Zhou, Y.*; Shen, J.*, Immunostimulatory AIE Dots for Live-Cell Imaging and Drug Delivery. ACS Applied Materials & Interfaces 2021, 13 (17), 19660-19667. Yang, Y.; Chen, B.; Zhai, T; Feng, L.; Shen, J.*; Wang, L., Recent Progress of Aggregation-induced Emission Molecular Oligomers. Acta Polymerica Sinica 2021, 52 (9), 1100-1117. Xia, K.#; Shen, J.#; Li, Q.; Fan, C.; Gu, H., Near-Atomic Fabrication with Nucleic Acids. ACS Nano 2020, 14 (2), 1319-1337. Shen, J.; Tao, K.; Gu, P.; Gui, C.; Wang, D.; Tan, Z.; Wang, L.; Wang, Z.; Qin, A.; Tang, B. Z.; Bao, S., Aggregation-induced emission luminogen for specific identification of malignant tumour in vivo. Science China-Chemistry 2020, 63 (3), 393-397. Zhai, T.; Li, Q.; Shen, J.*; Li, J.; Fan, C., DNA nanostructure-encoded fluorescent barcodes. Aggregate 2020, 1 (1), 107-116. Zhang, Y.#; Shen, J.#; Hu, R.; Shi, X.; Hu, X.; He, B.; Qin, A.; Tang, B. Z., Fast surface immobilization of native proteins through catalyst-free amino-yne click bioconjugation. Chemical Science 2020, 11 (15), 3931-3935. Shen, J.#; Liang, L.#; Xiao, M.#; Xie, X.; Wang, F.; Li, Q.; Ge, Z.; Li, J.; Shi, J.; Wang, L.; Li, L.; Pei, H.; Fan, C., Fractal Nanoplasmonic Labels for Supermultiplex Imaging in Single Cells. JACS. 2019, 141 (30), 11938-11946. Xie, M.; Li, F.; Gu, P.; Wang, F.; Qu, Z.; Li, J.; Wang, L.; Zuo, X.; Zhang, X.*; Shen, J.*, Gold nanoflower-based surface-enhanced Raman probes for pH mapping of tumor cell microenviroment. Cell Proliferation 2019, 52 (4). Shen, J.; Jiang, X.; Xu, L.; Ge, Z.; Li, Q.; Song, B.; Wang, L.; Song, S., Poly-Adenine-Engineered Gold Nanogaps for SERS Nanostructures. ACS Applied Nano Materials 2019, 2 (6), 3501-3509. Shen, J.; Zhang, Y.; Hu, R.; Kwok, R. T. K.; Wang, Z.; Qin, A.; Tang, B. Z., Dual-Mode Ultrasensitive Detection of Nucleic Acids via an Aqueous "Seesaw" Strategy by Combining Aggregation-Induced Emission and Plasmonic Colorimetry. ACS Applied Nano Materials 2019, 2 (1), 163-169.

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