Cook, Michael T. - University of Hertfordshire - Department of Pharmacy, Pharmacology and Postgraduate Medicine

个人简介

I am a lecturer in the pharmaceutics group and the Topical Drug Delivery and Toxicology research centre. I currently teach on the MPharm Pharmacy and MSc Pharmaceutical Sciences degrees. I am lead on the MSc module "Principles of Pharmaceutical Science". My main research interest is the development of novel materials for mucosal drug delivery, including: hydrogels, in situ gelling systems, micro- and nano- particles.

近期论文

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Internal nanoparticle structure of temperature-responsive self-assembled PNIPAM-b-PEG-b-PNIPAM triblock copolymers in aqueous solutions: NMR, SANS and Light Scattering studiesFilippov, S. K., Bogomolova, A. Y., Kaberov, L., Velychkivska, N., Starovoytova, L., Cernochova, Z., Rogers, S. E., Lau, W. M., Khutoryanskiy, V. V. & Cook, M. T. 9 May 2016 In : Langmuir : the ACS journal of surfaces and colloids.Article In Vitro Cell Models for Ophthalmic Drug Development ApplicationsShafaie, S., Hutter, V., Cook, M. T., Brown, M. & Chau, D. Y. S. Apr 2016 In : BioResearch Open Access. 5, 1, p. 94-108Article Mucoadhesion and mucosa-mimetic materials - a mini-reviewCook, M. T. & Khutoryanskiy, V. V. 30 Nov 2015 In : International Journal of Pharmaceutics. 495, 2, p. 991-998Article Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testingCook, M. T., Smith, S. L. & Khutoryanskiy, V. V. 2015 In : Chemical Communications. 51, p. 14447-14450Article Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio) ethylacrylate and 2-hydroxyethylmethacrylate: novel drug delivery systems for chemotherapeutic agents to the bladderCook, M. T., Schmidt, S. A., Lee, E., Samprasit, W., Opanasopit, P. & Khutoryanskiy, V. V. 2015 In : Journal of Materials Chemistry B. 3, 32, p. 6599-6604Article Microencapsulation of a synbiotic into PLGA/alginate multiparticulate gelsCook, M. T., Tzortzis, G., Charalampopoulos, D. & Khutoryanskiy, V. V. 15 May 2014 In : International Journal of Pharmaceutics. 466, 1-2, p. 400-408 9 p.Article Microencapsulation of probiotic bacteria into alginate hydrogelsCook, M. T., Charalampopoulos, D. & Khutoryanskiy, V. V. 14 Apr 2014 Hydrogels in Cell-Based Therapies. Connon, C. J. & Hamley, I. W. (eds.). Royal Society of Chemistry, p. 95-111 17 p. (RSC Soft Matter; no. 2)Chapter Investigation of milk proteins binding to the oral mucosaWithers, C. A., Cook, M. T., Methven, L., Gosney, M. A. & Khutoryanskiy, V. V. 1 Nov 2013 In : Food and Function. 4, 11, p. 1668-1674 7 p.Article Influence of encapsulation and coating materials on the survival of Lactobacillus plantarum and Bifidobacterium longum in fruit juicesNualkaekul, S., Cook, M. T., Khutoryanskiy, V. V. & Charalampopoulos, D. 1 Aug 2013 In : Food Research International. 53, 1, p. 304-311 8 p.Article CLSM method for the dynamic observation of pH change within polymer matrices for oral deliveryCook, M. T., Saratoon, T., Tzortzis, G., Edwards, A., Charalampopoulos, D. & Khutoryanskiy, V. V. 11 Feb 2013 In : Biomacromolecules. 14, 2, p. 387-393 7 p.Article Layer-by-layer coating of alginate matrices with chitosan-alginate for the improved survival and targeted delivery of probiotic bacteria after oral administrationCook, M. T., Tzortzis, G., Khutoryanskiy, V. V. & Charalampopoulos, D. 7 Jan 2013 In : Journal of Materials Chemistry B. 1, 1, p. 52-60 9 p.Article Chitosan coated alginate beads for the survival of microencapsulated Lactobacillus plantarum in pomegranate juiceNualkaekul, S., Lenton, D., Cook, M. T., Khutoryanskiy, V. V. & Charalampopoulos, D. 15 Oct 2012 In : Carbohydrate Polymers. 90, 3, p. 1281-1287 7 p.Article Microencapsulation of probiotics for gastrointestinal deliveryCook, M. T., Tzortzis, G., Charalampopoulos, D. & Khutoryanskiy, V. V. 20 Aug 2012 In : Journal of Controlled Release. 162, 1, p. 56-67 12 p.Article Production and evaluation of dry alginate-chitosan microcapsules as an enteric delivery vehicle for probiotic bacteriaCook, M. T., Tzortzis, G., Charalampopoulos, D. & Khutoryanskiy, V. V. 11 Jul 2011 In : Biomacromolecules. 12, 7, p. 2834-2840 7 p.Article