Shore, Angela - University of Exeter

个人简介

Professor Angela Shore is the inaugural Vice-Dean Research for the University of Exeter Medical School, and was previously Interim Vice-Dean Research for the Peninsula College of Medicine and Dentistry since 2009. She is the Scientific Director of the NIHR Exeter Clinical Research Facility for Experimental Medicine and Associate Director for Experimental Medicine for the UKCRN diabetes research network. Professor Shore graduated in Physiology from the University of Newcastle and was awarded her PhD for an investigation of the vascular mechanisms underlying fluid homeostasis in patients with Liver Disease. Following postdoctoral positions at the University of London where she expanded her research into the vascular aspects of hypertension, Professor Shore moved to the Postgraduate Medical School Exeter to establish the clinical microvascular research unit funded by the Wellcome Trust. Currently Professor Shore’s work which is funded by the British Heart Foundation, Diabetes UK, European Union IMI JU and NIHR investigates novel approaches to the identification of early vascular complications and patient stratification for cardiovascular risk. She was appointed Professor of Cardiovascular Science in 2000. As the Interim Vice Dean for Research and previously the Director for the Institute of Biomedical and Clinical Science, Professor Shore played a central role in the research success of the Peninsula College of Medicine and Dentistry, driving the research strategy, the appointment of new staff and the development of state of the art facilities. She also led the last three successful RAE submissions. Professor Shore is committed to interdisciplinary research and was instrumental in the establishment of the University of Exeter Science Strategy Theme “Translational Medicine, Personalised Medicine and Public Health” to drive forward this approach. Professor Shore is actively involved in Microcirculation research worldwide. She is Treasurer of the European Society for Microcirculation, and represents Europe on the International Liaison Committee.

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Iyengar SS, Morgan-Hughes G, Ukoumunne O, Clayton B, Davies EJ, Nikolaou V, Hyde CJ, Shore AC, Roobottom CA (2016). Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients. Clin Radiol, 71(2), 151-158. Abstract. Author URL. Article has an altmetric score of 1 Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract. Author URL. Article has an altmetric score of 1 Clark CE, Taylor RS, Butcher I, Stewart MC, Price J, Fowkes FG, Shore AC, Campbell JL (2016). Inter-arm blood pressure difference and mortality: a cohort study in an asymptomatic primary care population at elevated cardiovascular risk. Br J Gen Pract, 66(646), e297-e308. Abstract. Author URL. Full text. Article has an altmetric score of 139 Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract. Author URL. Full text. Thorn CE, Shore AC (2016). The role of perfusion in the oxygen extraction capability of skin and skeletal muscle. Am J Physiol Heart Circ Physiol, 310(10), H1277-H1284. Abstract. Author URL. Article has an altmetric score of 2 Clark C, Shore A, Taylor R, Campbell J (2015). 1C.08: THE INTER-ARM DIFFERENCE IN BLOOD PRESSURE AND MORTALITY: SYSTEMATIC REVIEW AND META-ANALYSIS. J Hypertens, 33 Suppl 1 Abstract. Author URL. Siervo M, Lara J, Jajja A, Sutyarjoko A, Ashor AW, Brandt K, Qadir O, Mathers JC, Benjamin N, Winyard PG, et al (2015). Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability: an individual participant meta-analysis. Nitric Oxide, 47, 97-105. Abstract. Author URL. Full text. Article has an altmetric score of 1 Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract. Author URL. Elyas S, Adingupu D, Aizawa K, Shore AC, Strain WD, Gates PE (2015). Cerebral hemodynamics in patients with large vessel disease stroke and lacunar stroke. INTERNATIONAL JOURNAL OF STROKE, 10, 368-368. Author URL. Shepherd AI, Gilchrist M, Winyard PG, Jones AM, Hallmann E, Kazimierczak R, Rembialkowska E, Benjamin N, Shore AC, Wilkerson DP, et al (2015). Effects of dietary nitrate supplementation on the oxygen cost of exercise and walking performance in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled crossover trial. Free Radic Biol Med, 86, 200-208. Abstract. Author URL. Full text. Article has an altmetric score of 1 Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract. Author URL. Article has an altmetric score of 2 Lewandowski AJ, Davis EF, Yu G, Digby JE, Boardman H, Whitworth P, Singhal A, Lucas A, Mccormick K, Shore AC, et al (2015). Elevated blood pressure in preterm-born offspring associates with a distinct antiangiogenic state and microvascular abnormalities in adult life. Hypertension, 65(3), 607-614. Abstract. Full text. Article has an altmetric score of 3 Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract. Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract. Author URL. Shepherd AI, Wilkerson DP, Dobson L, Kelly J, Winyard PG, Jones AM, Benjamin N, Shore AC, Gilchrist M (2015). The effect of dietary nitrate supplementation on the oxygen cost of cycling, walking performance and resting blood pressure in individuals with chronic obstructive pulmonary disease: a double blind placebo controlled, randomised control trial. Nitric Oxide, 48, 31-37. Abstract. Author URL. Article has an altmetric score of 8 Gooding KM, Shore AC, Ling R, Agardh E (2014). An evaluation of different methods of normalising fovea thickness measurements from optical coherence tomography instruments. DIABETOLOGIA, 57, S473-S473. Author URL. Gilchrist M, Winyard PG, Fulford J, Anning C, Shore AC, Benjamin N (2014). Dietary nitrate supplementation improves reaction time in type 2 diabetes: development and application of a novel nitrate-depleted beetroot juice placebo. Nitric Oxide, 40, 67-74. Abstract. Author URL. Full text. Article has an altmetric score of 11 Pienaar PR, Micklesfield LK, Gill JMR, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Experimental Physiology, 99(7), 985-994. Abstract. Pienaar PR, Micklesfield LK, Gill JM, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Exp Physiol, 99(7), 985-994. Abstract. Author URL. Pienaar PR, Micklesfield LK, Levitt NS, Gooding K, Shore AC, Goedecke JH, Gill JMR, Lambert EV (2014). Insulin Resistance is Associated with Lower Acetylcholine-Induced Microvascular Reactivity in Nondiabetic Women. Metabolic Syndrome and Related Disorders, 12(3), 178-184. Abstract.