Murray, Anna - University of Exeter

个人简介

Anna has a degree in biology from Southampton University, where she also completed her PhD, investigating the molecular biology of coeliac disease and T cell lymphoma of the gut. She spent 5 years as a postdoc in Professor Pat Jacobs‘ lab in Salisbury investigating the population genetics and molecular basis of fragile X syndrome. In 1998 Anna received a Career Development Fellowship from the Wellcome Trust to work on the association between the fragile X mutation and premature ovarian failure. Following a short career break to have her daughter, Anna moved to Exeter in 2005. Anna was appointed as a lecturer in 2008 and senior lecturer in 2011.

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Frayling TM, Tyrrell J (In Press). Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank. British Medical Journal Full text. Ruth KS, Perry JR, Henley WE, Melzer D, Weedon MN, Murray A (2016). Events in Early Life are Associated with Female Reproductive Ageing: a UK Biobank Study. Sci Rep, 6 Abstract. Author URL. Full text. Article has an altmetric score of 1 Ruth KS, Beaumont RN, Tyrrell J, Jones SE, Tuke MA, Yaghootkar H, Wood AR, Freathy RM, Weedon MN, Frayling TM, et al (2016). Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health. Hum Reprod, 31(2), 473-481. Abstract. Author URL. Full text. Article has an altmetric score of 6 Ruth KS, Campbell PJ, Chew S, Lim EM, Hadlow N, Stuckey BGA, Brown SJ, Feenstra B, Joseph J, Surdulescu GL, et al (2016). Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes. European Journal of Human Genetics, 24(2), 284-290. Abstract. Article has an altmetric score of 13 Ruth KS, Campbell PJ, Chew S, Lim EM, Hadlow N, Stuckey BG, Brown SJ, Feenstra B, Joseph J, Surdulescu GL, et al (2016). Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes. Eur J Hum Genet, 24(2), 284-290. Abstract. Author URL. Article has an altmetric score of 13 Pilling LC, Atkins JL, Bowman K, Jones SE, Tyrrell J, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Wood AR, et al (2016). Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Aging (Albany NY), 8(3), 547-560. Abstract. Author URL. Article has an altmetric score of 73 Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, et al (2016). Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med, 46(8), 1613-1623. Abstract. Author URL. Article has an altmetric score of 9 Wood AR, Tyrrell J, Beaumont R, Jones SE, Tuke MA, Ruth KS, GIANT consortium, Yaghootkar H, Freathy RM, Murray A, et al (2016). Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. Diabetologia, 59(6), 1214-1221. Abstract. Author URL. Full text. Article has an altmetric score of 15 Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, et al (2015). Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair. Obstetrical and Gynecological Survey, 70(12), 758-762. Article has an altmetric score of 1 Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, et al (2015). Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet, 47(11), 1294-1303. Abstract. Author URL. Full text. Article has an altmetric score of 108 Perry JR, Murray A, Day FR, Ong KK (2015). Molecular insights into the aetiology of female reproductive ageing. Nat Rev Endocrinol, 11(12), 725-734. Abstract. Author URL. Article has an altmetric score of 13 Day FR, Elks CE, Murray A, Ong KK, Perry JR (2015). Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study. Sci Rep, 5 Abstract. Author URL. Article has an altmetric score of 159 Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, et al (2015). Rare coding variants and X-linked loci associated with age at menarche. Nat Commun, 6 Abstract. Author URL. Article has an altmetric score of 20 Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, et al (2015). The transcriptional landscape of age in human peripheral blood. Nat Commun, 6 Abstract. Author URL. Article has an altmetric score of 165 Wood AR, Tuke MA, Nalls M, Hernandez D, Gibbs JR, Lin H, Xu CS, Li Q, Shen J, Jun G, et al (2015). Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes. Hum Mol Genet, 24(5), 1504-1512. Abstract. Author URL. Full text. Article has an altmetric score of 5 Perry JR, Hsu YH, Chasman DI, Johnson AD, Elks C, Albrecht E, Andrulis IL, Beesley J, Berenson GS, Bergmann S, et al (2014). DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Hum Mol Genet, 23(9), 2490-2497. Abstract. Author URL. Full text. Article has an altmetric score of 4 Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, et al (2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature, 514(7520), 92-97. Abstract. Author URL. Article has an altmetric score of 247 Murray A, Schoemaker MJ, Bennett CE, Ennis S, Macpherson JN, Jones M, Morris DH, Orr N, Ashworth A, Jacobs PA, et al (2014). Population-based estimates of the prevalence of FMR1 expansion mutations in women with early menopause and primary ovarian insufficiency. Genet Med, 16(1), 19-24. Abstract. Author URL. Full text. Article has an altmetric score of 6 Weedon MN, Cebola I, Patch AM, Flanagan SE, De Franco E, Caswell R, Rodríguez-Seguí SA, Shaw-Smith C, Cho CH, Lango Allen H, et al (2014). Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis. Nat Genet, 46(1), 61-64. Abstract. Author URL. Article has an altmetric score of 96 Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, et al (2013). A genome-wide association study of depressive symptoms. Biol Psychiatry, 73(7), 667-678. Abstract. Author URL. Full text.