Henley, William - University of Exeter

个人简介

BA (Hons) Mathematics (University of Oxford) MSc Statistics with Applications in Medicine (University of Southampton) PhD Applied Statistics (The Open University) Career William has worked as an applied statistician for over 20 years and has broad experience of statistical consultancy in academia and industry. He received his undergraduate training in Mathematics at the University of Oxford, before studying for a PhD at the Open University on statistical methods for credit scoring, under the supervision of Professor David Hand. William has held postdoctoral positions in statistical epidemiology at the University of Oxford and the Animal Health Trust. Prior to joining the University of Exeter, he was Associate Professor (Reader) in Statistics in the Centre for Health and Environmental Statistics at Plymouth University. In 2010, he was seconded to the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care for the South West Peninsula (PenCLAHRC). He was appointed to a Chair in Medical Statistics at UEMS in May 2012.

研究领域

Analysis of longitudinal, multilevel and survival data Quasi-experimental analytic methods for strengthening causal inference from observational studies Design and analysis of cohort and other epidemiological studies Epidemiology of ageing, disability and chronic disease Statistical methods in bioinformatics A current focus of his research is on the development and application of methodology for evaluating medical treatments using observational patient data. His collaborations include providing statistical leadership for the Exeter component of the Healthy Ageing theme of the NIHR National School for Public Health. Another growing area of research interest is the development of a statistical framework for treatment stratification for chronic diseases such as type 2 diabetes. Prof Henley gives an overview of his research into ways of using data to measure the effectiveness and safety of medical treatments, in the video below.

近期论文

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Norman SM, Ford T, Henley W, Goodman R (2016). A comparison of parent reported outcome with experience of services. Journal of Children's Services, 11(2), 157-169. Abstract. Full text. Article has an altmetric score of 1 Hunter JG, Madden RG, Stone AM, Osborne N, Wheeler B, Vine L, Dickson A, Barlow M, Lewis J, Bendall RP, et al (2016). Coastal clustering of HEV; Cornwall, UK. Eur J Gastroenterol Hepatol, 28(3), 323-327. Abstract. Author URL. Full text. Article has an altmetric score of 3 Ruth KS, Perry JR, Henley WE, Melzer D, Weedon MN, Murray A (2016). Events in Early Life are Associated with Female Reproductive Ageing: a UK Biobank Study. Sci Rep, 6 Abstract. Author URL. Full text. Article has an altmetric score of 1 Pilling LC, Joehanes R, Kacprowski T, Peters M, Jansen R, Karasik D, Kiel DP, Harries LW, Teumer A, Powell J, et al (2016). Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiol Genomics, 48(1), 1-11. Abstract. Author URL. Article has an altmetric score of 19 Bowman K, Delgado J, Henley WE, Masoli JA, Kos K, Brayne C, Thokala P, Lafortune L, Kuchel GA, Ble A, et al (2016). Obesity in Older People with and Without Conditions Associated with Weight Loss: Follow-up of 955,000 Primary Care Patients. J Gerontol a Biol Sci Med Sci Abstract. Author URL. Article has an altmetric score of 10 Lin NX, Henley WE (2016). Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach. Statistics in Medicine Abstract. Full text. Article has an altmetric score of 1 Eyre V, Lang CC, Smith K, Jolly K, Davis R, Hayward C, Wingham J, Abraham C, Green C, Warren FC, et al (2016). Rehabilitation Enablement in Chronic Heart Failure-a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial. BMJ Open, 6(10). Abstract. Author URL. Ble A, Hughes PM, Delgado J, Masoli JA, Bowman K, Zirk-Sadowski J, Mujica Mota RE, Henley WE, Melzer D (2016). Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156 Typical Older Patients: a Quasi-Experimental Study. J Gerontol a Biol Sci Med Sci Abstract. Author URL. Full text. Article has an altmetric score of 3 Jones AG, Lonergan M, Henley WE, Pearson ER, Hattersley AT, Shields BM (2016). Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?. PLoS One, 11(4). Abstract. Author URL. Full text. Article has an altmetric score of 1 Dennis JM, Hattersley AT, Henley WE, Jones AG, Pearson ER, Shields BM (2016). Stratification using gender and body mass index (BMI) can predict side-effect risk in people with Type 2 diabetes initiating thiazolidinediones but not sulphonylureas: a MASTERMIND study. DIABETIC MEDICINE, 33, 86-86. Author URL. Shields B, Dennis J, Rodgers L, Jones A, Lonergan M, Henley W, Holman R, Pearson E, Hattersley A, Consortium MASTERMIND, et al (2016). Stratification using gender and body mass index (BMI) results in better glycaemic control for longer: a MASTERMIND study. DIABETIC MEDICINE, 33, 10-11. Author URL. Abel A, Hayes AM, Henley W, Kuyken W (2016). Sudden gains in cognitive-behavior therapy for treatment-resistant depression: Processes of change. J Consult Clin Psychol, 84(8), 726-737. Abstract. Author URL. Article has an altmetric score of 10 Parker C, Marlow R, Kastner M, May F, Mitrofan O, Henley W, Ford T (2016). The "supporting kids, avoiding problems" (SKIP) study: Relationships between school exclusion, psychopathology, development and attainment - Case control study. Journal of Children's Services, 11(2), 91-110. Abstract. Full text. Article has an altmetric score of 1 Kuzma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJ, Comijs H, Chaves PH, Kestenbaum BR, Kuller LH, et al (2016). Vitamin D and Memory Decline: Two Population-Based Prospective Studies. J Alzheimers Dis, 50(4), 1099-1108. Abstract. Author URL. Full text. Article has an altmetric score of 94 Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PH, Kestenbaum BR, Kuller LH, Langa KM, et al (2016). Vitamin D and Risk of Neuroimaging Abnormalities. PLoS One, 11(5). Abstract. Author URL. Full text. Article has an altmetric score of 5 Ble A, Masoli JA, Barry HE, Winder RE, Tavakoly B, Henley WE, Kuchel GA, Valderas JM, Melzer D, Richards SH, et al (2015). Any versus long-term prescribing of high risk medications in older people using 2012 Beers Criteria: results from three cross-sectional samples of primary care records for 2003/4, 2007/8 and 2011/12. BMC Geriatr, 15 Abstract. Author URL. Full text. Article has an altmetric score of 6 Steel N, Hardcastle AC, Bachmann MO, Richards SH, Mounce LTA, Clark A, Lang I, Melzer D, Campbell JL (2015). Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. BMJ Open, 4(10). Abstract. Full text. Article has an altmetric score of 9 Metcalf BS, Hosking J, Henley WE, Jeffery AN, Mostazir M, Voss LD, Wilkin TJ (2015). Erratum to: Physical activity attenuates the mid-adolescent peak in insulin resistance but by late adolescence the effect is lost: a longitudinal study with annual measures from 9-16 years (EarlyBird 66). Diabetologia, 58(12). Author URL. Mounce LT, Barry HE, Calitri R, Henley WE, Campbell J, Roland M, Richards S (2015). Establishing the validity of English GP Patient Survey items evaluating out-of-hours care. BMJ Qual Saf Abstract. Author URL. Full text. Article has an altmetric score of 5 Metcalf BS, Hosking J, Jeffery AN, Henley WE, Wilkin TJ (2015). Exploring the Adolescent Fall in Physical Activity: a 10-yr Cohort Study (EarlyBird 41). Med Sci Sports Exerc, 47(10), 2084-2092. Abstract.