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个人简介

2006 MSci (hons), University of Glasgow 2011 DPhil, University of Oxford Career Dr Mick Craig completed his undergraduate degree in Neuroscience at the University of Glasgow in 2006. This degree included a year in the pharmaceutical industry, where he carried out schizophrenia research at Merck, Sharp and Dohme in Harlow, Essex. He then moved to the University of Oxford to study on a four year Wellcome Trust DPhil in the OXION programme, working with Prof Ole Paulsen and Dr Louise Upton, graduating in 2011. In the final year of Mick's doctoral studies, Prof Paulsen moved to the University of Cambridge to take up the Chair of Physiology, so once Mick completed his DPhil, he spent a few months in Cambridge before moving to the National Institutes of Health (Bethesda, USA) in 2011, to work as a Postdoctoral Visiting Fellow in the group of Dr Chris McBain. Mick moved back to the UK in early 2016 to establish his research group at the University of Exeter on a Research Fellowship funded by the Vandervell Foundation.

研究领域

My research group aims to determine how long-range connections allow different regions of the brain to synchronise their activity, with a particular focus on interactions between the prefrontal cortex, entorhinal cortex and the hippocampus. We are also interested in understanding how inhibitory interneurons can control network behaviour: although interneurons make up only a minority of cortical neurons, they play a fundamental role in coordinating and pacing the activity of principal cells. We use a combination of behavioural, electrophysiological (in vitro and in vivo), optogenetic and viral tracing techniques to unravel the cellular circuitry through which prefrontal-entorhinal-hippocampal dialogues are established, and to study how interneurons can shape network dynamics.

近期论文

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Craig MT, McBain CJ (2015). Fast gamma oscillations are generated intrinsically in CA1 without the involvement of fast-spiking basket cells. Journal of Neuroscience, 35(8), 3616-3624. Abstract. Article has an altmetric score of 2 Craig MT, McBain CJ (2015). Navigating the circuitry of the brain's GPS system: Future challenges for neurophysiologists. Hippocampus, 25(6), 736-743. Author URL. Article has an altmetric score of 2 Pelkey KA, Barksdale E, Craig MT, Yuan X, Sukumaran M, Vargish GA, Mitchell RM, Wyeth MS, Petralia RS, Chittajallu R, et al (2015). Pentraxins coordinate excitatory synapse maturation and circuit integration of parvalbumin interneurons. Neuron, 85(6), 1257-1272. Abstract. Article has an altmetric score of 3 Craig MT, McBain CJ (2014). The emerging role of GABAB receptors as regulators of network dynamics: Fast actions from a 'slow' receptor?. Current Opinion in Neurobiology, 26, 15-21. Abstract. Article has an altmetric score of 3 Matta JA, Pelkey KA, Craig MT, Chittajallu R, Jeffries BW, McBain CJ (2013). Developmental origin dictates interneuron AMPA and NMDA receptor subunit composition and plasticity. Nat Neurosci, 16(8), 1032-1041. Abstract. Author URL. Article has an altmetric score of 3 Craig MT, Mayne EW, Bettler B, Paulsen O, Mcbain CJ (2013). Distinct roles of GABAB1a- and GABAB1b-containing GABAB receptors in spontaneous and evoked termination of persistent cortical activity. Journal of Physiology, 591(4), 835-843. Abstract. Mayne EW, Craig MT, Mcbain CJ, Paulsen O (2013). Dopamine suppresses persistent network activity via D1-like dopamine receptors in rat medial entorhinal cortex. European Journal of Neuroscience, 37(8), 1242-1247. Abstract. Article has an altmetric score of 4 Chittajallu R, Craig MT, Mcfarland A, Yuan X, Gerfen S, Tricoire L, Erkkila B, Barron SC, Lopez CM, Liang BJ, et al (2013). Dual origins of functionally distinct O-LM interneurons revealed by differential 5-HT3AR expression. Nature Neuroscience, 16(11), 1598-1607. Abstract. Article has an altmetric score of 2 Rodríguez-Moreno A, González-Rueda A, Banerjee A, Upton AL, Craig MT, Paulsen O (2013). Presynaptic Self-Depression at Developing Neocortical Synapses. Neuron, 77(1), 35-42. Abstract.

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