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学习工作经历: 2006/09-2012/12,南京农业大学,动物医学院基础兽医系,博士,导师,赵茹茜教授 2001/09-2005/06,西南农业大学,动物科技学院动物医学系学士 2013/3-至今,南京农业大学,动物医学院,讲师 主持或参加科研项目(课题) 1. 国家自然科学基金青年基金项目,31402161,日粮中添加亚精胺对断奶仔猪 肌肉生长抑素表达的影响及其表遗传调控机制,2015/01 -2017/12, 22万元, 在研, 主持 2. 江苏省自然科学基金青年基金项目,BK20140692,母源性亚精胺对新生仔猪 肝脏自噬的影响及其表遗传机制,2014/7-2017/7, 20万元, 在研, 主持 3. 农业部农产品质量安全监管(饲料)项目,蛋氨酸羟基类似物保育猪的安全 性评价,2014/01 -2014/12, 25万元, 结题, 主持 4. 国家自然科学基金面上项目,31572482,炎症状态下GR和NF-ΚB介导的猪脂 肪组织ZAG转录调控研究,2016/01-2019/12,65万元,在研,参加。 5. 国家自然科学基金青年项目,20873999,细菌内毒素干扰TFAM线粒体定位诱 发猪精子氧化损伤的分子机制,2016/01-2018/12,20万元,在研,参加

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(1) Jia Y#, Hong J#, Li H, Hu Y, Jia L, Cai D, Zhao R*. Butyrate stimulates adipose lipolysis and mitochondrial oxidative phosphorylation through histone hyperacetylation-associated β(3) -adrenergic receptor activation in high-fat diet-induced obese mice. Exp Physiol. 2017 Feb 1;102(2):273-281. (2) Jia Y, Ling M, Zhang L, Jiang S, Sha Y, Zhao R*. Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets. J Agric Food Chem. 2016 Oct 12;64(40):7530-7539. (3) Hong J#, Jia Y#, Pan S, Jia L, Li H, Han Z, Cai D, Zhao R*. Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice. Oncotarget. 2016 Aug 30;7(35):56071-56082. (4) Jia Y, Song H, Gao G, Cai D, Yang X, Zhao R*. Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets. J Agric Food Chem. 2015 Nov 25;63(46):10152-60. (5) Jia Y, Gao G, Song H, Cai D, Yang X, Zhao R*. Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets. Eur J Nutr. 2016 Apr;55(3):1307-14. (6) Jia Y, Li R, Cong R, Yang X, Sun Q, Parvizi N, Zhao R*. Maternal low-protein diet affects epigenetic regulation of hepatic mitochondrial DNA transcription in a sex-specific manner in newborn piglets associated with GR binding to its promoter. PLoS One. 2013 May 14;8(5):e63855. doi: 10.1371/journal.pone.0063855. (7) Jia Y, Cong R, Li R, Yang X, Sun Q, Parvizi N, Zhao R*. Maternal low-protein diet induces gender-dependent changes in epigenetic regulation of the glucose-6-phosphatase gene in newborn piglet liver. J Nutr. 2012 Sep;142(9):1659-65. (8) Zou H#, Li R#, Jia Y#, Yang X, Ni Y, Cong R, Soloway PD, Zhao R*. Breed-dependent transcriptional regulation of 5'-untranslated GR (NR3C1) exon 1 mRNA variants in the liver of newborn piglets. PLoS One. 2012;7(7):e40432.

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