Love, John - University of Exeter - Disciplines of Biosciences

个人简介

1991-1994 PhD Cell & Molecular Biology, University of Edinburgh 1986-1990 BSc Biological Sciences, University of St Andrews Career 2011-present Associate Professor in Plant and Industrial Biotechnology, College of Life and Environmental Sciences, University of Exeter 2007-2011 Senior Lecturer in Plant Molecular Biology, School of Biosciences, University of Exeter 2003-2007 Lecturer in Developmental Biology, School of Biosciences, University of Exeter 2001-2003 Independent Broodbank Research Fellow, Department of Plant Sciences, University of Cambridge 1996-2001 Postdoctoral Research Associate, NASA Specialized Center for Research & Training, North Carolina State University 1995-1996 Postdoctoral Research Assistant, Institute of Cell & Molecular Biology, University of Edinburgh

研究领域

The laboratory was established in the Autumn of 2003 and uses state-of-the-art molecular and cell biology to investigate cell signalling in plants during the vegetative-floral transition. In the long-term, this research aims to provide new understanding of systemic signalling in plants through the interaction between transductive models of cell signalling and inductive, transcriptional models of flowering. I have previously shown that circadian and diurnal Ca2+ oscillations may encode information regarding the length of the light-dark cycle in which plants are grown, and are pursuing this observation further. I have developed A. thaliana that are impaired in circadian Ca2+ signalling, and am using these as well as mutant plants to investigate the role of Ca2+-mediated signal transduction. The laboratory is particularly interested in applying and developing recombinant technologies to image and quantify metabolites and cellular signalling components, particularly ascorbate and Ca2+. To facilitate this goal, we have developed several cross-disciplinary collaborations, most notably with Dr. N. Smirnoff (metabolic signalling). The laboratory fosters a collaborative approach to science in pure and applied research, and has partnerships within Exeter University, the South-West and Internationally.

近期论文

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Tennant RK, Jones RT, Brock F, Cook CG, Love J, Turney CSM, Lee R (In Press). A New Flow Cytometry Method Enabling Rapid Purification of Fossil Pollen from Terrestrial Sediments for AMS Radiocarbon Dating. Journal of Quaternary Science Xiaodong X, Hotta CT, Dodd AN, Love J, Sharrock R, Young WL, Qiguang X, Johnson CH, Webb AAR (In Press). Distinct Light and Clock Modulation of Cytosolic Free Ca2+ Oscillations and Rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 Promoter Activity in Arabidopsis. The Plant Cell, 19(11), 3474-3490. Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (In Press). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. PNAS Abstract. Author URL. Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract. Author URL. Full text. Littlejohn GR, Mansfield JC, Parker D, Lind R, Perfect S, Seymour M, Smirnoff N, Love J, Moger J (2015). In vivo chemical and structural analysis of plant cuticular waxes using stimulated Raman scattering microscopy. Plant Physiol, 168(1), 18-28. Abstract. Author URL. Full text. Littlejohn GR, Mansfield JC, Christmas JT, Witterick E, Fricker MD, Grant MR, Smirnoff N, Everson RM, Moger J, Love J, et al (2014). An update: improvements in imaging perfluorocarbon-mounted plant leaves with implications for studies of plant pathology, physiology, development and cell biology. Front Plant Sci, 5 Abstract. Author URL. Full text. Article has an altmetric score of 3 Lux TM, Lee R, Love J (2014). Genome-wide phylogenetic analysis of the pathogenic potential of Vibrio furnissii. Front Microbiol, 5 Abstract. Author URL. Article has an altmetric score of 1 Hutt H, Everson R, Grant M, Love J, Littlejohn G (2014). How clumpy is my image?. Soft Computing Abstract. Hutt H, Everson R, Grant M, Love J, Littlejohn G (2014). How clumpy is my image?: Scoring in crowdsourced annotation tasks. Soft Computing, 19(6), 1541-1552. Abstract. Love J, Tennant RK, Jones RT, Lee R (2013). A new flow cytometry enabling purification of diatoms from silica-rich lacustrine sediments. Journal of Limnology, 49(2), 305-309. Abstract. Tennant RK, Jones RT, Brock F, Cook C, Turney CSM, Love J, Lee R (2013). A new flow cytometry method enabling rapid purification of fossil pollen from terrestrial sediments for AMS radiocarbon dating. Journal of Quaternary Science, 28(3), 229-236. Abstract. Article has an altmetric score of 3 Reid EL, Weynberg KD, Love J, Isupov MN, Littlechild JA, Wilson WH, Kelly SL, Lamb DC, Allen MJ (2013). Functional and structural characterisation of a viral cytochrome b5. FEBS Lett, 587(22), 3633-3639. Abstract. Author URL. Article has an altmetric score of 1 Hutt H, Everson R, Grant M, Love J, Littlejohn G (2013). How clumpy is my image? Evaluating crowdsourced annotation tasks. 2013 13th UK Workshop on Computational Intelligence, UKCI 2013, 136-143. Abstract. Full text. Littlejohn GR, Love J (2012). A simple method for imaging Arabidopsis leaves using perfluorodecalin as an infiltrative imaging medium. Journal of visualized experiments : JoVE(59). Abstract. Debieux CM, Dridge EJ, Mueller CM, Splatt P, Paszkiewicz K, Knight I, Florance H, Love J, Titball RW, Lewis RJ, et al (2011). A bacterial process for selenium nanosphere assembly. Proc Natl Acad Sci U S A, 108(33), 13480-13485. Abstract. Author URL. Full text. Reid EL, Worthy CA, Probert I, Ali ST, Love J, Napier J, Littlechild JA, Somerfield PJ, Allen MJ (2011). Coccolithophores: functional biodiversity, enzymes and bioprospecting. Mar Drugs, 9(4), 586-602. Abstract. Author URL. Lux TM, Lee R, Love J (2011). Complete genome sequence of a free-living Vibrio furnissii sp. nov. strain (NCTC 11218). J Bacteriol, 193(6), 1487-1488. Author URL. Article has an altmetric score of 3 Love J (2010). Conference report: Society for general microbiology bioenergy fuel sources symposium. Biofuels, 1(1), 15-17. Littlejohn GR, Gouveia JD, Edner C, Smirnoff N, Love J (2010). Perfluorodecalin enhances in vivo confocal microscopy resolution of Arabidopsis thaliana mesophyll. New Phytol, 186(4), 1018-1025. Abstract. Article has an altmetric score of 3 Dodd AN, Gardner MJ, Hotta CT, Hubbard KE, Dalchau N, Robertson FC, Love J, Sanders D, Webb AAR (2009). Response to comment on "the Arabidopsis circadian clock incorporates a cADPR-based feedback loop". Science, 326(5950).