Kulak, Nora - Freie Universität Berlin

个人简介

2011 – present Assistant professor Freie Universität Berlin Institute of Chemistry and Biochemistry 2008 – 2010 Postdoc Massachusetts Institute of Technology (MIT), Cambridge/MA, USA Department of Chemistry, Supervisor Prof. Dr. Stephen Lippard 2006 – 2008 Postdoc Federal Institute for Materials Research and Testing (BAM), Berlin, Germany Surface and Thin Film Analysis, Supervisor Dr. Wolfgang Unger 2003 – 2006 PhD thesis Ruprecht-Karls-Universität Heidelberg, Germany Institute of Inorganic Chemistry, Supervisor Prof. Dr. Roland Krämer 1998 – 2003 Studies Ruprecht-Karls-Universität Heidelberg, Germany

研究领域

metal complexes with biological functions

近期论文

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Mononuclear Cu(II) and Zn(II) complexes with a simple diamine ligand: synthesis, structure, phosphodiester binding and DNA cleavage studies P. Sureshbabu, A. A. J. Sudarga Tjakraatmadja, C. Hanmandlu, K. Elavarasan, N. Kulak*, S. Sabiah* RSC Adv. 2015, 5, 22405–22418. Copper complexes of N-donor ligands as artificial nucleases C. Wende, C. Lüdtke, N. Kulak* Eur. J. Inorg. Chem. 2014, 2597-2612 (invited review article with cover picture and profile). Reaction of a bis(benzoylhydrazone) with copper(II): complex formation, hydroxylation and DNA cleavage activity S. Rodríguez-Hermida, C. Wende, A. B. Lago, R. Carballo, N. Kulak*, E. M. Vázquez-López* Eur. J. Inorg. Chem. 2013, 5843-5853. Nanoparticle encapsulation of mitaplatin and the effect thereof on in vivo properties T. C. Johnstone, N. Kulak, E. M. Pridgen, O. C. Farokhzad, R. Langer, S. J. Lippard* ACS Nano 2013, 7, 5675-5683. Straightforward approach to efficient oxidative DNA cleaving agents based on Cu(II) complexes of heterosubstituted cyclens J. Hormann, C. Perera, N. Deibel, D. Lentz, B. Sarkar, N. Kulak* Dalton Trans. 2013, 42, 4357-4360. Redox activation of metal-based prodrugs as a strategy for drug delivery N. Graf, S. J. Lippard* Adv. Drug Deliv. Rev. 2012, 64, 993-1004. αVβ3 integrin-targeted PLGA-PEG nanoparticles for enhanced anti-tumor efficacy of a Pt(IV) prodrug N. Graf, D. Bielenberg, N. Kolishetti, C. Muus, J. Banyard, O. C. Farokhzad, S. J. Lippard* ACS Nano 2012, 6, 4530-4539 (highlighted in "In Nano"). Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells N. Graf, T. E. Mokhtari, I. Papayannopoulos, S. J. Lippard* J.Inorg. Biochem. 2012, 110, 58-63.