个人简介

发明专利 和玉兵; 一种可见光下裸眼可视的植物遗传转化的无损筛选系统、构建方法及其应用. 202010934705.6; 2020. 和玉兵, 占华东; 一种提高获得基因编辑植株概率的筛选系统、构建方法及其应用; 202010934721.5; 2020. 和玉兵; 一种监测DNA顺式元件在植物中表达模式的无损报告系统、构建方法及其应用; 202010934723.4; 2020. 和玉兵; 一种快速高效获得非转基因的定向基因突变植株的方法和应用; PCT/CN2019/087139; 2019. 赵云德, 和玉兵; 一种快速高效获得非转基因的定向基因突变植株的方法和应用; 201810464473.5; 2018. 赵云德, 王荣臣, 张涛, 和玉兵, 杨宁; 一种植物基因组多位点编辑载体pCXUN-CAS9-RGR; 201710384742.2; 2017.

研究领域

遗传学、分子生物学、植物基因工程

1. 植物基因组编辑技术开发 重点关注高效广适性植物基因编辑技术体系开发。在Molecular Plant、Plant Physiology、Horticulture Research等学术期刊发表基因编辑相关学术论文十余篇。着眼于植物基因组编辑中存在的科学问题与技术瓶颈，开发相关解决方案。首创快速高效自主清除转基因的植物基因编辑技术（TKC）以及可见光下裸眼可视的新型报告系统（RUBY），有效简化了遗传转化、基因编辑、顺式元件分析等研究操作。两种解决方案已被国内外数百家实验室用于相关研究。 2. 植物激素作用机理研究 利用基因编辑技术研究植物中激素相关基因的互作和调控网络。克隆并研究了首例导致水稻柱头完全退化的基因，为新型杂交水稻制种提供了理想的材料。

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

He Y*#, Zhang T#, Sun H, Zhan H, Zhao Y*. A reporter for noninvasively monitoring gene expression and plant transformation. Hortic Res, 2020, 7: 152. He Y*#, Zhu M#, Wu J#, Ouyang L, Wang R, Sun H, Yan L, Wang L, Xu M, Zhan H, Zhao Y. Repurposing of anthocyanin biosynthesis for plant transformation and genome editing. Front Genome Ed, 2020, doi: 10.3389/fgeed.2020.607982. He Y, Zhao Y*. Technological breakthroughs in generating transgene-free and genetically stable CRISPR-edited plants. aBIOTECH, 2020, 1(1): 88-96. He Y, Yan L, Ge C, Yao XF, Han X, Wang R, Xiong L, Jiang L, Liu CM, Zhao Y*. PINOID Is Required for Formation of the Stigma and Style in Rice. Plant Physiol, 2019, 180(2): 926-936. He Y, Zhu M, Wang L, Wu J, Wang Q, Wang R, Zhao Y*. Improvements of TKC Technology Accelerate Isolation of Transgene-Free CRISPR/Cas9-Edited Rice Plants. Rice Sci, 2019, 26(2): 109-117. He Y, Zhu M, Wang L, Wu J, Wang Q, Wang R, Zhao Y*. Programmed Self-Elimination of the CRISPR/Cas9 Construct Greatly Accelerates the Isolation of Edited and Transgene-Free Rice Plants. Mol Plant, 2018, 11(9): 1210-1213. He Y, Zhang T, Yang N, Xu M, Yan L, Wang L, Wang R, Zhao Y*. Self-cleaving ribozymes enable the production of guide RNAs from unlimited choices of promoters for CRISPR/Cas9 mediated genome editing. J Genet Genomics, 2017, 44(9): 469-472. He Y, Wang R, Dai X, Zhao Y*. On Improving CRISPR for Editing Plant Genes: Ribozyme-Mediated Guide RNA Production and Fluorescence-Based Technology for Isolating Transgene-Free Mutants Generated by CRISPR. Prog Mol Biol Transl Sci, 2017, 149: 151-166. He Y, Zhao Y*. A key link between jasmonic acid signaling and auxin biosynthesis. Sci China Life Sci, 2015, 58(3): 311-312. Wang Y, Wei S, He Y, Yan L, Wang R, Zhao Y*. Synergistic roles of LAX1 and FZP in the development of rice sterile lemma. The Crop Journal, 2020, 8(1): 16-25. Li S, Li J, He Y, Xu M, Zhang J, Du W, Zhao Y*, Xia L*. Precise gene replacement in rice by RNA transcript-templated homologous recombination. Nat Biotechnol, 2019, 37(4): 445-450. Sun Y, Zhang X, Wu C, He Y, Ma Y, Hou H, Guo X, Du W, Zhao Y*, Xia L*. Engineering Herbicide-Resistant Rice Plants through CRISPR/Cas9-Mediated Homologous Recombination of Acetolactate Synthase. Mol Plant, 2016, 9(4): 628-631.