个人简介
October 1985 Post-doctoral Researcher, Institute of Plant Science Research, Cambridge.
August 1988 Lecturer, Department of Biology, University of Essex
October 1995 Senior Lecturer, Biological Sciences, University of Essex
October 2002 Reader, Biological Sciences, University of Essex
October 2004 Professor, Biological Sciences, University of Essex
研究领域
My main research interest is in primary carbon metabolism which started with the isolation and characterisation of the genes encoding the enzymes of the Calvin cycle. Since 1995 a major focus in my laboratory has been to investigate the relative importance of individual enzymes in the Calvin cycle in controlling the rate of carbon fixation and plant growth. We are now extending this work to study the regulation of carbon metabolism by investigating the stromal proteins that regulate the Calvin cycle enzymes. I am also interested in how growth of plant in elevated CO2 affects photosynthetic capacity in field conditions
Transgenic manipulation of chloroplast carbon metabolism - identification of factors limiting photosynthesis and yield
Proteomic approaches to redox mediated protein-protein interactions in the regulation of metabolism
The role of plant biotechnology in the production of plants for improved yield for food and fu
Photosynthetic carbon metabolism and links to thiamine biosynthesis
近期论文
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1. Mahdi Khozeai, Stuart Fisk, Tracy Lawson, Yves Gibon, Ronan Sulpice, M Stitt, Stephane C Lefebvre, Christine A Raines (2015) Overexpression of plastid transketolase in tobacco results in a thiamine auxotrophic phenotype Plant Cell (in press)
2. Driever M, Lawson T, Andralojc P J, Raines CA, Parry MA J (2014) Natural variation in photosynthetic capacity, growth and yield in 64 field grown wheat genotypes. J Exp Bot. 64, 4959-4973
3. McKew BA, Lefebvre SC, Achterberg EP, Metodieva G, RainesCA, Metodi M, Geider RJ (2013) Plasticity in the proteome of Emiliania huxleyi CCMP 1516 to extremes of light is highly targeted. New Phytologist 200, 61-73
4. McKew BA, Davey P, Finch SJ, Hopkins J, Lefebvre SC, Metodi MV, Oxborough K, Raines CA, Lawson T, Geider RJ (2013) The trade-off between the light-harvesting and photoprotective functions of fucoxanthin-chlorophyll proteins dominates light acclimation in Emiliania huxleyi (clone CCMP 1516). New Phytologist 200, 74-85
5. Stanley DN, Raines CA, Kerfeld CA (2013) Comparative Analysis of 126 Cyanobacterial Genomes Reveals Evidence of Functional Diversity Among Homologs of the Redox-Regulated CP12 Protein. Plant Physiol 161, 824-835
6. Rosenthal DM, Locke A, Khozaei,M, Raines CA, Long SP, Ort DR (2011) Over-expressing the C3 photosynthesis cycle enzyme Sedoheptulose-1-7 Bisphosphatase improves photosynthetic carbon gain and yield under fully open air CO2 fumigation (FACE) BMC Biology 11, 123 -131
7. Howard TP, Upton G, Lloyd JC, Raines CA (2011) Antisense suppression of the small chloroplast protein CP12. A transcriptional viewpoint. Plant Sig Behav 6, 12, 1-5
8. Howard TP, Fryer MJ, Singh P, Metodiev M, Lytovchenko A, Obata T, Fernie AR, Kruger NJ, Quick WP, Lloyd JC, and Raines CA (2011) Antisense Suppression of the Small Chloroplast Protein CP12 in Tobacco Alters Carbon Partitioning and Severely Restricts Growth. Plant Phys 157, 620-631
9. Howard TP, Lloyd JC, Raines CA (2011) Inter-species variation in the oligomeric states of the higher plant Calvin cycle enzymes glyceraldehyde-3-phosphate dehydrogenase and phosphoribulokinase J Exp Bot 62, 3799-3805
10. Groben R, Kaloudas D, Raines CA, Offmann B, Maberly SC, Gontero B (2010) Comparativein photosynthetic organisms Photosynth Res 103, 183–194
11. Lefebvre SC, Harris G, Webster R, Read B, Garrido J, Leonardos N, Geider RJ, Raines CA (2010) Characterisation and expression analysis of the Lhcf gene family in Emiliania huxleyi (Haptophyta) reveals differential responses to light and CO2. J Phycol 46, 123–134
12. Parry MAJ, Reynolds M, Salvucci ME, Raines CA, Andralojc JP, Zhu X-G, G. Price, D Condon AT, and Furbank RT (2010) Raising yield potential of wheat. II. Increasing photosynthetic capacity and efficiency. J Exp Bot doi:10.1093/jxb/erq304.
13. Howard TP, Metodiev M, Lloyd JC, Raines CA (2008) Thioredoxin-mediated reversible dissociation of a stromal mulitprotein complex in response to changes in light availability. Proc Natl Acad Sci 105, 4056-4061
14. Singh P, Kaloudas D, Raines CA (2008) Expression analysis of the Arabidopsis CP12 gene family suggests novel roles for these proteins in roots and floral tissues. J Exp Bot 59, 3975–3985
15. Lawson T, Bryant B, Lefebvre S, Lloyd JC, Raines CA. (2006) Decreased SBPase activity alters growth and development in transgenic tobacco plants. Plant Cell Environ 29, 48-58
16. Lawson T, Bryant B, Lefebvre S, Lloyd JC, Raines CA. (2006) Decreased SBPase activity alters growth and development in transgenic tobacco plants. Plant Cell Environ 29, 48-58
17. P A Davey, H Olcer, O Zakhleniuk , C J Bernacchi , C Calfapietra, SP Long, CA Raines (2006) Can fast growing plantation trees escape biochemical down-regulation of photosynthesis when grown throughout their complete production cycle in the field under elevated carbon dioxide? Plant Cell Environ 29, 1235-1244
18. Lefebvre S., Lawson T., Zakhleniuk O.V., Lloyd J.C., Raines C.A. (2005) Increased sedoheptulose-1,7-bisphosphatase activity in transgenic tobacco plants stimulates photosynthesis and growth from an early stage in development. Plant Physiology 138, 451- 460
19. Caemmerer SV, Lawson T, Oxborough K, Baker N, Andrews TJ, Raines CA (2004) Stomatal conductance does not correlate with photosynthetic capacity in transgenic plants with reduced amounts of Rubisco. J Exp Bot 55, 1157-1166
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